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Tetraspanin 12 (TSPAN12) ELISA Kits

The protein encoded by TSPAN12 is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Additionally we are shipping TSPAN12 Antibodies (46) and TSPAN12 Proteins (3) and many more products for this protein.

list all ELISA KIts Gene Name GeneID UniProt
Anti-Human TSPAN12 TSPAN12 23554 O95859
Anti-Mouse TSPAN12 TSPAN12 269831 Q8BKT6
Anti-Rat TSPAN12 TSPAN12 362326 Q569A2
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More ELISA Kits for TSPAN12 Interaction Partners

Human Tetraspanin 12 (TSPAN12) interaction partners

  1. Among the patients with pathogenic mutations detected, FZD4 (show FZD4 ELISA Kits) mutations accounted for the largest proportion of autosomal inheritance FEVR (show NDP ELISA Kits) cases (13/18 patients, 72.2%), followed by LRP5 (show LRP5 ELISA Kits) (4/18 patients, 22.2%) and TSPAN12 (1/18 patients, 5.6%).

  2. Here we describe a case of a female infant affected by cystic fibrosis (show S100A8 ELISA Kits) and by a severe form of exudative vitreoretinopathy. In particular, we have detected the homozygous missense mutation c.668 T > C in TSPAN12.

  3. Novel mutation in TSPAN12 leads to autosomal recessive inheritance of congenital vitreoretinal disease with intra-familial phenotypic variability.

  4. Novel mutations have been described in the TSPAN12 gene in Chinese patients with familial exudative vitreoretinopathy.

  5. These results suggest that stroma-derived p53 (show TP53 ELISA Kits) plays a pivotal role in epithelial cancer progression and that TSPAN12 and CXCL6 are potential targets for lung cancer therapy.

  6. TSPAN12 plays a role in supporting primary tumor growth and suppressing metastasis.

  7. This study is the first report of recessive mutations in TSPAN12 and shows that patients with two mutant alleles have a severe form of FEVR (show NDP ELISA Kits) or retinal dysplasia, whereas heterozygous family members have mild familial exudative vitreoretinopathy phenotypes

  8. The largest miRNA-146a-TSPAN12 response to stress of amyloidbeta peptide + tumor necrosis factoralpha is found in human neuronal glial cells from Alzheimer brain.

  9. We speculate that haploinsufficiency of TSPAN12 contributes to PHPV.

  10. TSPAN12 mutations are responsible for familial exudative vitreoretinopathy (FEVR (show NDP ELISA Kits)). The phenotypes associated with TSPAN12 mutations showed great variations between different individuals within a family and between the two eyes in individual patients.

Mouse (Murine) Tetraspanin 12 (TSPAN12) interaction partners

  1. Data indicate that Norrin (show NDP ELISA Kits) multimers and TSPAN12 cooperatively promote multimerization of FZD4 (show FZD4 ELISA Kits) and its associated proteins to elicit physiological levels of signaling.

TSPAN12 Antigen Profile

Antigen Summary

The protein encoded by this gene is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility.

Gene names and symbols associated with Tetraspanin 12 (TSPAN12) ELISA Kits

  • tetraspanin 12 (Tspan12) antibody
  • tetraspanin 12 (LOC100220256) antibody
  • tetraspanin 12 (TSPAN12) antibody
  • tetraspanin 12 (tspan12) antibody
  • 9030619E17 antibody
  • AI426782 antibody
  • AI663988 antibody
  • AW111457 antibody
  • EVR5 antibody
  • NET-2 antibody
  • NET2 antibody
  • Tm4sf12 antibody
  • zgc:63880 antibody

Protein level used designations for Tetraspanin 12 (TSPAN12) ELISA Kits

tetraspanin 12 , tetraspanin-12 , transmembrane 4 superfamily member 12 , tspan-12 , tetraspan NET-2

GENE ID SPECIES
412465 Apis mellifera
100220256 Taeniopygia guttata
100603513 Nomascus leucogenys
394127 Danio rerio
417763 Gallus gallus
23554 Homo sapiens
612262 Canis lupus familiaris
613639 Bos taurus
269831 Mus musculus
362326 Rattus norvegicus
100174568 Pongo abelii
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