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Tetraspanin 8 Proteins (TSPAN8)

The protein encoded by TSPAN8 is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Additionally we are shipping Tetraspanin 8 Antibodies (42) and Tetraspanin 8 Kits (1) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
TSPAN8 7103 P19075
TSPAN8 216350 Q8R3G9
Rat TSPAN8 TSPAN8 171048  
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Top Tetraspanin 8 Proteins at

Showing 4 out of 7 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Human Cells Human His tag 10 μg Log in to see 16 Days
Insect Cells Mouse rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific pu... 0.25 mg Log in to see 49 to 54 Days
Insect Cells Human rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific pu... 0.5 mg Log in to see 49 to 54 Days
HOST_Wheat germ Human GST tag 10 μg Log in to see 9 Days

TSPAN8 Proteins by Origin and Source

Origin Expressed in Conjugate
Human , ,
, , ,
Mouse (Murine)

Top referenced Tetraspanin 8 Proteins

  1. Human Tetraspanin 8 Protein expressed in Human Cells - ABIN2006626 : Betz, Sadler: Variants of a cloned synthetic lactose operator. I. A palindromic dimer lactose operator derived from one stand of the cloned 40-base pair operator. in Gene 1981 (PubMed)

More Proteins for Tetraspanin 8 (TSPAN8) Interaction Partners

Xenopus laevis Tetraspanin 8 (TSPAN8) interaction partners

  1. overexpression of tm4sf3 promoted development of annular pancreas.

Human Tetraspanin 8 (TSPAN8) interaction partners

  1. Our data suggest that TSPAN8-LEL may play an important role in mCRC cell invasion, and that the antibody we have developed could be a useful tool for inhibiting the invasion of TSPAN8-expressing mCRCs.

  2. Based on nasopharyngeal TSPAN8 gene expression in readily available Nasopharyngeal aspirate samples , we can discriminate between severity of disease in Respiratory syncytial virus infected infants.

  3. CO-029 functions as a regulator of both cell-matrix and cell-cell adhesion. During colon cancer progression, CO-029 promotes cancer cell movement by deregulating cell adhesions.

  4. PMA-induced Tspan8-internalization promotes cell migration, but reduces matrix and cell adhesion.

  5. High TSPAN8 is associated with melanoma invasiveness.

  6. claudin-7 (show CLDN7 Proteins)-associated EpCAM (show EPCAM Proteins) is recruited into (tetraspanin-enriched membrane microdomains) and forms a complex with CO-029 and CD44v6 that facilitates metastasis formation

  7. overexpression of TM4SF3 in esophageal cancer conferred advantage to the invasion and metastasis of this destructive disease

Mouse (Murine) Tetraspanin 8 (TSPAN8) interaction partners

  1. results argue for a role for Tspan8 in body-weight regulation in males, but do not show differences in T2D-associated traits that were anticipated from previous human genome-wide association studies.

  2. Results suggest that alterations in gene expression of Gata6 (show GATA6 Proteins), Tspan8, S100a8 (show S100A8 Proteins), and Lmo2 (show LMO2 Proteins) may act via novel pathways that play functionally important roles in Men1 (show MEN1 Proteins)-associated tumor progression.

Tetraspanin 8 (TSPAN8) Protein Profile

Protein Summary

The protein encoded by this gene is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. This encoded protein is a cell surface glycoprotein that is known to complex with integrins. This gene is expressed in different carcinomas. The use of alternate polyadenylation sites has been found for this gene.

Gene names and symbols associated with Tetraspanin 8 Proteins (TSPAN8)

  • tetraspanin 8 (tspan8)
  • tetraspanin 8 (Tspan8)
  • tetraspanin 8 (TSPAN8)
  • C76990 protein
  • CO-029 protein
  • CO-29 protein
  • E330007O21Rik protein
  • GB13255 protein
  • MGC64550 protein
  • tetraspanin-8 protein
  • Tm4sf3 protein
  • TSPAN-8 protein
  • TSPAN8 protein

Protein level used designations for Tetraspanin 8 Proteins (TSPAN8)

tetraspanin 8 , transmembrane 4 superfamily member 3 , tetraspanin-8 , tspan-8 , tumor-associated antigen CO-029 , D6.1A

380553 Xenopus laevis
409511 Apis mellifera
417854 Gallus gallus
496915 Xenopus (Silurana) tropicalis
718622 Macaca mulatta
743174 Pan troglodytes
474448 Canis lupus familiaris
7103 Homo sapiens
216350 Mus musculus
171048 Rattus norvegicus
617508 Bos taurus
100174494 Pongo abelii
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