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TPK1 encodes a protein, that exists as a homodimer, which catalyzes the conversion of thiamine to thiamine pyrophosphate. Additionally we are shipping TPK1 Proteins (22) and TPK1 Kits (6) and many more products for this protein.
Showing 10 out of 35 products:
Human Polyclonal TPK1 Primary Antibody for ICC, IF - ABIN4361492
Mayr, Freisinger, Schlachter, Rolinski, Zimmermann, Scheffner, Haack, Koch, Ahting, Prokisch, Sperl: Thiamine pyrophosphokinase deficiency in encephalopathic children with defects in the pyruvate oxidation pathway. in American journal of human genetics 2011
Human Polyclonal TPK1 Primary Antibody for EIA, IHC (p) - ABIN955185
Bohn, Winckler: Isolation and characterization of four new placental tissue proteins (PP18, PP19, PP20, PP21). in Archives of gynecology 1985
Cow (Bovine) Polyclonal TPK1 Primary Antibody for WB - ABIN2774107
Fradin, Bougneres: Three common intronic variants in the maternal and fetal thiamine pyrophosphokinase gene (TPK1) are associated with birth weight. in Annals of human genetics 2007
stress response, and/or fecundity of isp-1(qm150) Mit mutants relative to wild-type animals
These findings demonstrate that the genes involved in dictating thiamine homeostasis, such as SLC19A2 (show SLC19A2 Antibodies), SLC25A19 (show SLC25A19 Antibodies) and TPK-1, were significantly up-regulated in clinical tissues and breast cancer cell lines.
Mutation analysis of TPK1 uncovered three missense, one splice-site, and one frameshift mutation resulting in decreased TPK protein levels
findings indicate the importance of the Sp1 transcription factor (show SP1 Antibodies) cis (show CISH Antibodies)-element in regulating the human thiamin pyrophosphokinase gene (hTPK1) gene expression
Genomic variations in either the fetal or maternal TPK1 gene could contribute to variability of birth weight in normal humans.
Three-dimensional structure of thiamine pyrophosphokinase crystallized from an equilibrium substrate/product mixture shows clear electron density for pyrithiamine pyrophosphate bound in the enzyme active site.
This gene encodes a protein, that exists as a homodimer, which catalyzes the conversion of thiamine to thiamine pyrophosphate. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.
thiamin pyrophosphokinase 1
, hypothetical protein
, thiaminepyrophosphokinase 1
, placental protein 20
, thiamine diphosphokinase
, thiamine kinase
, thiamine pyrophosphokinase
, thiamine pyrophosphokinase 1