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anti-Thiopurine S-Methyltransferase (TPMT) Antibodies

TPMT encodes the enzyme that metabolizes thiopurine drugs via S-adenosyl-L-methionine as the S-methyl donor and S-adenosyl-L-homocysteine as a byproduct. Additionally we are shipping TPMT Proteins (24) and TPMT Kits (10) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
TPMT 22017 O55060
TPMT 7172 P51580
TPMT 690050  
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Top anti-TPMT Antibodies at antibodies-online.com

Showing 10 out of 92 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Mouse Un-conjugated EIA, WB 0.1 mL Log in to see 6 to 8 Days
$412.50
Details
Human Rabbit Un-conjugated WB 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Mouse Un-conjugated IF, IHC (p), ELISA, WB Immunoperoxidase of monoclonal antibody to TPMT on formalin-fixed paraffin-embedded human spleen. [antibody concentration 1 ug/ml] Immunofluorescence of monoclonal antibody to TPMT on HeLa cell. [antibody concentration 10 ug/ml] 100 μg Log in to see 9 Days
$430.00
Details
Human Mouse Un-conjugated ELISA, WB Detection limit for recombinant GST tagged TPMT is approximately 0.03ng/ml as a capture antibody. Western Blot detection against Immunogen (52.69 KDa) . 100 μg Log in to see 9 Days
$430.00
Details
Human Mouse Un-conjugated ELISA, WB 100 μL Log in to see 8 to 10 Days
$478.50
Details
Human Mouse Un-conjugated IF, IHC (p), WB 100 μL Log in to see 8 to 10 Days
$493.17
Details
Human Mouse Un-conjugated IHC (p), WB 100 μL Log in to see 8 to 10 Days
$493.17
Details
Human Mouse Un-conjugated IHC, WB Immunohistochemical staining of paraffin-embedded Kidney tissue using anti-TPMT mouse monoclonal antibody. (ABIN2453729, Dilution 1:50) Immunohistochemical staining of paraffin-embedded liver tissue using anti-TPMT mouse monoclonal antibody. (ABIN2453729, Dilution 1:50) 100 μL Log in to see 2 to 3 Days
$423.50
Details
Human Mouse Un-conjugated IF, IHC, WB Immunohistochemical staining of paraffin-embedded breast tissue using anti-TPMT mouse monoclonal antibody. (ABIN2453730, Dilution 1:50) Immunohistochemical staining of paraffin-embedded Adenocarcinoma of breast tissue using anti-TPMT mouse monoclonal antibody. (ABIN2453730, Dilution 1:50) 100 μL Log in to see 2 to 3 Days
$423.50
Details
Human Mouse Un-conjugated FACS, IHC, WB Immunohistochemical staining of paraffin-embedded liver tissue using anti-TPMT mouse monoclonal antibody. (ABIN2453731, Dilution 1:50) Immunohistochemical staining of paraffin-embedded Carcinoma of liver tissue using anti-TPMT mouse monoclonal antibody. (ABIN2453731, Dilution 1:50) 100 μL Log in to see 2 to 3 Days
$482.90
Details

TPMT Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
Mouse (Murine)


Human , ,
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Rat (Rattus)


Top referenced anti-TPMT Antibodies

  1. Human Monoclonal TPMT Primary Antibody for IF, IHC (p) - ABIN563239 : Egle, Milek, Mlinaric-Rascan, Fahr, Kristl: A novel gene delivery system for stable transfection of thiopurine-S-methyltransferase gene in versatile cell types. in European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft für Pharmazeutische Verfahrenstechnik e.V 2008 (PubMed)
    Show all 2 references for ABIN563239

  2. Human Monoclonal TPMT Primary Antibody for EIA, WB - ABIN781549 : Odani, Nakamura, Sato, Fujii: Identification of a rat 30-kDa protein recognized by the antibodies to a recombinant rat cutaneous fatty acid-binding protein as a 14-3-3 protein. in Journal of biochemistry 2001 (PubMed)

  3. Human Monoclonal TPMT Primary Antibody for ELISA, WB - ABIN563241 : Hayashi, Naoi, Nakagawa, Nishikawa, Fukuda, Imajoh-Ohmi, Kondo, Kubo, Yabuki, Hattori, Hirouchi, Sugiyama: Sorting nexin 27 interacts with multidrug resistance-associated protein 4 (MRP4) and mediates internalization of MRP4. in The Journal of biological chemistry 2012 (PubMed)

More Antibodies against TPMT Interaction Partners

Mouse (Murine) Thiopurine S-Methyltransferase (TPMT) interaction partners

  1. These findings support the notion that germline polymorphisms in Tpmt affect not only host tissue toxicity but also antitumor effectiveness.

  2. suggestion that differential mouse TPMT activity is due to variation in mRNA expression

Human Thiopurine S-Methyltransferase (TPMT) interaction partners

  1. structure-function relationships of TPMT

  2. The TPMT promoter region may serve as a pharmacogenomic biomarker when introducing thiopurine therapy

  3. The most frequently occurring nonfunctional TPMT allele in Croatian population is TPMT*3A. Variant genotypes were statistically significantly more common in Crohn's disease subgroup than in ulcerative colitis subgroup.

  4. Association of TPMT polymorphisms with overall azathioprine-induced adverse drug reactions, bone marrow toxicity and gastric intolerance, but not with hepatotoxicity (meta-analysis).

  5. association of TPMT polymorphisms with overall thiopurine-induced adverse drug reactions

  6. Identification of TPMT variants and subsequent dose reduction reduces hematologic events during thiopurine treatment of inflammatory bowel disease.

  7. TPMT*3c mutant allele was associated with azathioprine side effects (leukopenia, alopecia) in Chinese systemic lupus erythematosus patients.

  8. refinements in risk stratification and treatment have reduced the influence of TPMT genotype on treatment outcome in a contemporary protocol.

  9. We report on the presence of the TPMT*3C and *3A mutant alleles in the Libyan population. Therefore, monitoring the patients to be treated with doses of thiopurine drugs for TPMT variants is worthwhile to avoid the development of severe myelosuppression.

  10. this paper shows that the influence of TPMT and COMT (show COMT Antibodies) on the development of cisplatin-induced hearing loss may be less important than previously suggested.

TPMT Antigen Profile

Protein Summary

This gene encodes the enzyme that metabolizes thiopurine drugs via S-adenosyl-L-methionine as the S-methyl donor and S-adenosyl-L-homocysteine as a byproduct. Thiopurine drugs such as 6-mercaptopurine are used as chemotherapeutic agents. Genetic polymorphisms that affect this enzymatic activity are correlated with variations in sensitivity and toxicity to such drugs within individuals. A pseudogene for this locus is located on chromosome 18q.

Gene names and symbols associated with TPMT

  • thiopurine S-methyltransferase (tpmt) antibody
  • zgc:101684 (zgc:101684) antibody
  • thiopurine S-methyltransferase (tpm) antibody
  • thiopurine S-methyltransferase (MCA0794) antibody
  • thiopurine S-methyltransferase (Pnap_4948) antibody
  • thiopurine S-methyltransferase (Hhal_1383) antibody
  • thiopurine S-methyltransferase (TK90_1044) antibody
  • thiopurine S-methyltransferase (Slit_1144) antibody
  • thiopurine S-methyltransferase (Tint_0842) antibody
  • Thiopurine S-methyltransferase (Fbal_3334) antibody
  • thiopurine S-methyltransferase (Celly_3188) antibody
  • thiopurine S-methyltransferase (Weevi_1737) antibody
  • Thiopurine S-methyltransferase (Psefu_2696) antibody
  • Thiopurine S-methyltransferase (Metme_3860) antibody
  • thiopurine methyltransferase (Tpmt) antibody
  • thiopurine S-methyltransferase (TPMT) antibody
  • thiopurine S-methyltransferase (Tpmt) antibody
  • AW106912 antibody
  • MGC84277 antibody
  • NHLRC1 antibody

Protein level used designations for TPMT

thiopurine S-methyltransferase , Thiopurine S-methyltransferase , S-adenosyl-L-methionine:thiopurine S-methyltransferase , thiopurine methyltransferase , NHL repeat containing 1

GENE ID SPECIES
447769 Xenopus laevis
573111 Danio rerio
1168449 Shewanella oneidensis MR-1
3104309 Methylococcus capsulatus str. Bath
4685796 Polaromonas naphthalenivorans CJ2
4711327 Halorhodospira halophila SL1
8806802 Thioalkalivibrio sp. K90mix
8891817 Sideroxydans lithotrophicus ES-1
9151573 Thiomonas intermedia K12
9772187 Ferrimonas balearica DSM 9799
10265228 Cellulophaga lytica DSM 7489
10282995 Weeksella virosa DSM 16922
10657285 Pseudomonas fulva 12-X
10673875 Methylomonas methanica MC09
22017 Mus musculus
7172 Homo sapiens
403536 Canis lupus familiaris
511644 Bos taurus
690050 Rattus norvegicus
493759 Felis catus
100034066 Equus caballus
100009411 Oryctolagus cuniculus
471863 Pan troglodytes
Selected quality suppliers for anti-TPMT (TPMT) Antibodies
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