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Thioredoxin 2 Proteins (TXN2)

This nuclear gene encodes a mitochondrial member of the thioredoxin family, a group of small multifunctional redox-active proteins. Additionally we are shipping Thioredoxin 2 Antibodies (80) and Thioredoxin 2 Kits (1) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
TXN2 9757 Q9UMN6
TXN2 56551 P97493
TXN2 79462 P97615
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Top Thioredoxin 2 Proteins at antibodies-online.com

Showing 10 out of 21 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Human His tag 100 μg Log in to see 2 to 3 Days
$217.80
Details
HOST_Escherichia coli (E. coli) Human His tag 100 μg Log in to see 16 Days
$272.80
Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Escherichia coli (E. coli) Human Un-conjugated 100 μg Log in to see 2 to 3 Days
$414.75
Details
HOST_Escherichia coli (E. coli) Human Un-conjugated 100 μg Log in to see 7 to 8 Days
$407.00
Details
Yeast Yeast His tag   1 mg Log in to see 56 to 66 Days
$2,185.33
Details
Yeast Cow His tag   1 mg Log in to see 56 to 66 Days
$2,196.33
Details
Yeast Rat His tag   1 mg Log in to see 56 to 66 Days
$2,196.33
Details
HOST_Escherichia coli (E. coli) Human His tag   0.1 mg Log in to see 2 to 3 Days
$412.50
Details

TXN2 Proteins by Origin and Source

Origin Expressed in Conjugate
Human ,

Mouse (Murine)

Rat (Rattus)

Top referenced Thioredoxin 2 Proteins

  1. Human TXN2 Protein expressed in Escherichia coli (E. coli) - ABIN2181878 : Chen, Cai, Murphy, Jones: Overexpressed human mitochondrial thioredoxin confers resistance to oxidant-induced apoptosis in human osteosarcoma cells. in The Journal of biological chemistry 2002 (PubMed)
    Show all 4 references for ABIN2181878

  2. Human TXN2 Protein expressed in Escherichia coli (E. coli) - ABIN2005261 : Choudhary, Kumar, Gnad, Nielsen, Rehman, Walther, Olsen, Mann: Lysine acetylation targets protein complexes and co-regulates major cellular functions. in Science (New York, N.Y.) 2009 (PubMed)
    Show all 3 references for ABIN2005261

  3. Human TXN2 Protein expressed in Escherichia coli (E. coli) - ABIN667715 : Wang, Zhang, Li, Le: Study of interactions between arsenicals and thioredoxins (human and E. coli) using mass spectrometry. in Rapid communications in mass spectrometry : RCM 2007 (PubMed)
    Show all 2 references for ABIN667715

More Proteins for Thioredoxin 2 (TXN2) Interaction Partners

Fruit Fly (Drosophila melanogaster) Thioredoxin 2 (TXN2) interaction partners

  1. This is the first demonstration of biochemical and physiological consequences caused by loss of Trx-2 in Drosophila.

  2. gene for thioredoxin (DmTrx-2) was cloned and expressed, and the protein characterized

  3. Drosophila thioredoxin can function as an anti-aging agent and as a suppressor of Parkin-associated endothelin receptor-like receptor - and poly-glutamine-induced neurotoxicity

  4. Trx-2 affects lifespan in Drosophila. Mutants have a decreased lifespan.

Human Thioredoxin 2 (TXN2) interaction partners

  1. The results explain how the MLL (show MLL Proteins) SET domains of MLL1 and MLL4 are able to add multiple methyl groups to the target histone H3 (show HIST3H3 Proteins) lysine.

  2. The Aven RGG/RG motif bound G4 structures within the coding regions of the MLL1 and MLL4 mRNAs increasing their polysomal association and translation, resulting in the induction of transcription of leukemic genes.

  3. We propose that MLL3 and MLL4 are broadly required for controlling MAFA (show KLRG1 Proteins) and MAFB (show MAFB Proteins) transactivation during development and postnatally.

  4. Thioredoxin 2 Is a Novel E2-Interacting Protein That Inhibits the Replication of Classical Swine Fever Virus by promoting the nuclear translocation of the p65 (show GORASP1 Proteins) subunit of NF-kappaB (show NFKB1 Proteins).

  5. HBV-MLL4 integration occurred frequently in Chinese HCC (show FAM126A Proteins) patients, representing a unique molecular segment for HCC (show FAM126A Proteins) with HBV infection

  6. Chromosomal translocation in a pediatric undifferentiated spindle cell sarcoma have characterized this alteration to show rearrangement of the MLL4 and GPS2 (show GPS2 Proteins) genes, resulting in fusion gene MLL4-GPS2 (show GPS2 Proteins), the expression of which promotes independent growth.

  7. The Grx2 (show GRX2 Proteins) system could help to keep Trx2/1 reduced during an oxidative stress, thereby contributing to the anti-apoptotic signaling.

  8. CERKL (show CERKL Proteins) interacts with TRX2 and plays a novel key role in the regulation of the TRX2 antioxidant pathway.

  9. TGF-beta (show TGFB1 Proteins)-mediated expression of the epithelial-mesenchymal transition marker fibronectin (show FN1 Proteins) was inhibited not only by chemicals that interfere with reactive oxygen species signaling but also by exogenously expressed mitochondrial thioredoxin.

  10. We showed that overexpression of TRXs reduced cell death; TRX2 was expressed in the mitochondria, while TRX1 (show MLL Proteins) was expressed in the cytoplasm.

Mouse (Murine) Thioredoxin 2 (TXN2) interaction partners

  1. The ventral signal observed from early stages colocalized with motor neuron markers Isl1 (show ISL1 Proteins)/2 and FoxP1 (show FOXP1 Proteins) and the strong ventral signal colocalizing with Isl1 (show ISL1 Proteins)/2 was observed in all rostrocaudal segments of the spinal cord.

  2. TRX-2 overexpression does not mitigate adverse effects of a high-calorie diet on synaptic plasticity

  3. An essential role was identified for thioredoxin-2 in preserving cardiac function by suppressing mitochondrial reactive oxygen species.

  4. The SirT1 (show SIRT1 Proteins) regulates the expression of several antioxidant genes in bovine aortic endothelial cells, including Mn superoxide dismutase (show SOD2 Proteins), catalase (show CAT Proteins), peroxiredoxins 3 and 5, thioredoxin 2, thioredoxin reductase 2 (show TXNRD2 Proteins), and uncoupling protein 2 (show UCP2 Proteins).

  5. This study shows that both fructose and glucose-sweetened liquid consumption results in fatty liver and upregulated thioredoxin-2 expression.

  6. Both thioredoxin 2 and glutaredoxin 2 (show GRX2 Proteins) contribute to the reduction of the mitochondrial 2-Cys (show DNAJC5 Proteins) peroxiredoxin Prx3 (show PRDX3 Proteins).

  7. Data show that Nrf2 (show NFE2L2 Proteins) activity was increased in WT MEFs at the 0 or -46 mV conditions, but was inhibited in Trx2 Tg MEFs under the same conditions.

  8. the rapid E2-mediated activation of the Txn (show TXN Proteins) pathway is an important step in the response of the mammalian uterus to estrogen.

  9. Trx2 is an endogenous regulator of the mitochondrial permeability transition.

Thioredoxin 2 (TXN2) Protein Profile

Protein Summary

This nuclear gene encodes a mitochondrial member of the thioredoxin family, a group of small multifunctional redox-active proteins. The encoded protein may play important roles in the regulation of the mitochondrial membrane potential and in protection against oxidant-induced apoptosis.

Gene names and symbols associated with Thioredoxin 2 Proteins (TXN2)

  • thioredoxin-2 (Trx-2)
  • thioredoxin 2 (TXN2)
  • thioredoxin 2 (Trx-2)
  • thioredoxin 2 (VPA0972)
  • thioredoxin 2 (PBPRB0824)
  • thioredoxin 2 (PBPRB1771)
  • Thioredoxin 2 (VS_II0704)
  • thioredoxin 2 (VCD_000568)
  • thioredoxin 2 (VEA_000083)
  • thioredoxin 2 (trx2)
  • lysine (K)-specific methyltransferase 2B (KMT2B)
  • thioredoxin 2 (Txn2)
  • thioredoxin 2 (txn2)
  • 31884 protein
  • 2510006J11Rik protein
  • AI788873 protein
  • anon-WO0118547.188 protein
  • CG3864 protein
  • CG31884 protein
  • DmelTrx-2 protein
  • Dmel\\CG31884 protein
  • dmtrx-2 protein
  • DTrx-2 protein
  • HRX2 protein
  • MLL1B protein
  • MLL2 protein
  • MLL4 protein
  • MT-TRX protein
  • MTRX protein
  • Trx protein
  • Trx2 protein
  • WBP7 protein
  • zgc:77127 protein

Protein level used designations for Thioredoxin 2 Proteins (TXN2)

CG31884-PA , CG31884-PB , Thioredoxin-2 , Trx-2-PA , Trx-2-PB , thioredoxin , thioredoxin, mitochondrial , thioredoxin 2 , Thioredoxin 2 , KMT2D , WBP-7 , WW domain binding protein 7 , WW domain-binding protein 7 , histone-lysine N-methyltransferase 2B , histone-lysine N-methyltransferase MLL4 , lysine N-methyltransferase 2B , lysine N-methyltransferase 2D , mixed lineage leukemia gene homolog 2 , myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila) 4 , myeloid/lymphoid or mixed-lineage leukemia 4 , myeloid/lymphoid or mixed-lineage leukemia protein 4 , trithorax homolog 2 , trithorax homologue 2 , mitochondrial thioredoxin , thioredoxin-2 , MTRX , mt-Trx , thioredoxin nuclear gene encoding mitochondrial protein

GENE ID SPECIES
34281 Drosophila melanogaster
426978 Gallus gallus
409451 Apis mellifera
1191661 Vibrio parahaemolyticus RIMD 2210633
3120857 Photobacterium profundum SS9
3121811 Photobacterium profundum SS9
7137998 Vibrio splendidus LGP32
7853783 Vibrio cholerae MJ-1236
8558388 Vibrio sp. Ex25
9897753 Achromobacter xylosoxidans A8
9757 Homo sapiens
25828 Homo sapiens
56551 Mus musculus
79462 Rattus norvegicus
402938 Danio rerio
379758 Xenopus laevis
474519 Canis lupus familiaris
281557 Bos taurus
100158080 Sus scrofa
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