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anti-Thioredoxin Interacting Protein (TXNIP) Antibodies

regulates thioredoxin to play an important role in the preservation of cellular viability [RGD, Feb 2006].. Additionally we are shipping TXNIP Kits (39) and TXNIP Proteins (7) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
TXNIP 10628 Q9H3M7
TXNIP 56338 Q8BG60
TXNIP 117514 Q5M7W1
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Top anti-TXNIP Antibodies at antibodies-online.com

Showing 10 out of 83 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Cow Rabbit Un-conjugated WB WB Suggested Anti-TXNIP Antibody Titration: 0.2-1 ug/mlELISA Titer: 1:62500Positive Control: Human heart 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Mouse Un-conjugated IHC (p), IP, WB 0.1 mg Log in to see 6 to 8 Days
$445.50
Details
Human Rabbit Un-conjugated WB WB Suggested Anti-TXNIP Antibody Titration: 0.2-1 ug/mlELISA Titer: 1:312500Positive Control: Human Lung WB Suggested Anti-TXNIP  Antibody Titration: 0.2-1 µg/mL ELISA Titer: 1:.12500  Positive Control: Human Lung 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Rabbit Un-conjugated WB TXNIP Antibody (N-term) (ABIN1881962) western blot analysis in NCI-H292 cell line lysates (35 µg/lane). This demonstrates the TXNIP antibody detected the TXNIP protein (arrow). 400 μL Log in to see 10 to 11 Days
$324.50
Details
Mouse Rabbit Un-conjugated WB Mouse Txnip Antibody (Center) (ABIN1881961) western blot analysis in mouse stomach tissue lysates (35 µg/lane). This demonstrates the Mouse Txnip antibody detected the Mouse Txnip protein (arrow). 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Rabbit Un-conjugated IHC (p), WB Human Spleen: Formalin-Fixed, Paraffin-Embedded (FFPE) 50 μg Log in to see 8 to 10 Days
$676.50
Details
Human Rabbit Un-conjugated WB 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Mouse Un-conjugated IP, WB 0.1 mg Log in to see 6 to 8 Days
$423.50
Details
Human Rabbit Un-conjugated WB 50 μg Log in to see 8 to 10 Days
$551.83
Details
Human Rabbit Un-conjugated WB 100 μg Log in to see 8 to 10 Days
$507.83
Details

TXNIP Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
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Top referenced anti-TXNIP Antibodies

  1. Human Monoclonal TXNIP Primary Antibody for IHC (p), IP - ABIN567794 : Saxena, Chen, Shalev: Intracellular shuttling and mitochondrial function of thioredoxin-interacting protein. in The Journal of biological chemistry 2010 (PubMed)
    Show all 6 references for ABIN567794

  2. Mouse (Murine) Polyclonal TXNIP Primary Antibody for WB - ABIN1881961 : Martin: [Growing old]. in Revue médicale suisse 2010 (PubMed)
    Show all 5 references for ABIN1881961

  3. Human Polyclonal TXNIP Primary Antibody for WB - ABIN1881962 : Zhuo, Niu, Chen, Xin, Guo, Mao: Vitamin D3 up-regulated protein 1(VDUP1) is regulated by FOXO3A and miR-17-5p at the transcriptional and post-transcriptional levels, respectively, in senescent fibroblasts. in The Journal of biological chemistry 2010 (PubMed)
    Show all 4 references for ABIN1881962

  4. Cow (Bovine) Polyclonal TXNIP Primary Antibody for WB - ABIN2784817 : Stoltzman, Peterson, Breen, Muoio, Billin, Ayer: Glucose sensing by MondoA:Mlx complexes: a role for hexokinases and direct regulation of thioredoxin-interacting protein expression. in Proceedings of the National Academy of Sciences of the United States of America 2008 (PubMed)

More Antibodies against TXNIP Interaction Partners

Human Thioredoxin Interacting Protein (TXNIP) interaction partners

  1. These findings thereby provide new mechanistic insight into the regulation of TXNIP and beta-cell biology and reveal novel links between proinflammatory cytokines, carbohydrate response element binding protein (show MLXIPL Antibodies)-mediated transcription, and microRNA signaling.

  2. The crystal structure of the complex between a phosphorylated PPxY motif of TXNIP and the SH2 domain of Vav2 (show VAV2 Antibodies) reveals a conserved recognition mechanism.

  3. Activation of the miR (show MLXIP Antibodies)-373-TXNIP-HIF1alpha (show HIF1A Antibodies)-TWIST signaling axis is correlated with a worse outcome in patients with breast cancer.

  4. Metformin down-regulates high-glucose-induced TXNIP transcription by inactivating ChREBP (show MLXIPL Antibodies) and FOXO1 (show FOXO1 Antibodies) in endothelial cells, partially through AMP-activated protein kinase (show PRKAA2 Antibodies) activation

  5. Foam cell-released 4-hydroxnonenal activates PPARdelta (show PPARD Antibodies) in Vascular endothelial cells, leading to increased TXNIP expression and consequently to senescence.

  6. our data support the hypothesis that TXNIP is an effective target for the treatment of breast cancer.

  7. Expression of TXNIP was up-regulated in all three NSCLC cell lines.

  8. Data identify the metastasis suppressor TXNIP as new target of miR (show MLXIP Antibodies)-224/miR (show MLXIP Antibodies)-452 that induces feedback inhibition of E2F1 (show E2F1 Antibodies) and show that miR (show MLXIP Antibodies)-224/452-mediated downregulation of TXNIP is essential for E2F1 (show E2F1 Antibodies)-induced EMT (show ITK Antibodies) and invasion

  9. HG-induced NADPH oxidase (show NOX1 Antibodies) activation is driven by TXNIP which subsequently triggers NALP3 (show NLRP3 Antibodies) inflammasome activation in podocytes and ultimately led to podocyte injury

  10. Suggest that TXNIP plays a critical role in anti-Her-1 (show EGFR Antibodies)/Her-2 (show ERBB2 Antibodies) treatment and may be a potential prognostic marker in breast cancer.

Pig (Porcine) Thioredoxin Interacting Protein (TXNIP) interaction partners

  1. The molecular characterization of porcine TXNIP gene, is described.

  2. single-marker and haplotype analyses revealed significant effects of TXNIP on hot carcass weight, test daily gain, and lifetime daily gain

Cow (Bovine) Thioredoxin Interacting Protein (TXNIP) interaction partners

  1. Foam cell-released 4-hydroxnonenal activates PPARdelta (show PPARD Antibodies) in Vascular endothelial cells, leading to increased TXNIP expression and consequently to senescence.

Mouse (Murine) Thioredoxin Interacting Protein (TXNIP) interaction partners

  1. ITCH targets TXNIP for ubiquitin-proteasome degradation in cardiomyocytes and ameliorates reactive oxygen species-induced cardiotoxicity through the thioredoxin (show TXN Antibodies) system.

  2. These findings thereby provide new mechanistic insight into the regulation of TXNIP and beta-cell biology and reveal novel links between proinflammatory cytokines, carbohydrate response element binding protein (show MLXIPL Antibodies)-mediated transcription, and microRNA signaling.

  3. Txnip plays an important role in oxidative inflammatory response and atherosclerotic lesion development in ApoE (show APOE Antibodies) knockout mice.

  4. The results indicate that a lack of TxNIP protects against diabetic nephropathy (DN) and support in vitro data that upregulation of TxNIP by glucose is a key mediator of early oxidative stress and a trigger for the development and progression of DN.

  5. Reactive oxygen species regulation through REDD1 (show DDIT4 Antibodies)/TXNIP is physiological rheostat controlling stress-induced autophagy.

  6. These findings suggest that TXNIP is required for endothelial cell survival and homeostasis especially under stress conditions including hyperoxia.

  7. HG-induced NADPH oxidase (show NOX1 Antibodies) activation is driven by TXNIP which subsequently triggers NALP3 (show NLRP3 Antibodies) inflammasome activation in podocytes and ultimately led to podocyte injury

  8. Data indicate that thioredoxin-interacting protein (TXNIP)levels are induced in erythroid differentiation.

  9. In vivo, levels of lipogenic proteins, inflammatory molecules, PGC-1alpha (show PPARGC1A Antibodies), and PRMT1 (show PRMT1 Antibodies) were increased in the livers of HFD mice compared with those fed a chow diet, and were ameliorated in HFD Txnip(-/-) mice.

  10. we demonstrated that TXNIP-mediated NLRP3 (show NLRP3 Antibodies) inflammasome activation in cardiac microvascular endothelial cells was a novel mechanism of myocardial ischemia/reperfusion injury

TXNIP Antigen Profile

Protein Summary

regulates thioredoxin to play an important role in the preservation of cellular viability

Gene names and symbols associated with TXNIP

  • thioredoxin interacting protein (txnip) antibody
  • thioredoxin interacting protein (TXNIP) antibody
  • thioredoxin interacting protein (Txnip) antibody
  • 1200008J08Rik antibody
  • AA682105 antibody
  • EST01027 antibody
  • HHCPA78 antibody
  • Hyplip1 antibody
  • Tbp-2 antibody
  • THIF antibody
  • Vdup1 antibody

Protein level used designations for TXNIP

thioredoxin interacting protein , Thioredoxin-interacting protein , thioredoxin binding protein 2 , thioredoxin-binding protein 2 , thioredoxin-interacting protein , upregulated by 1,25-dihydroxyvitamin D-3 , vitamin D3 up-regulated protein 1 , hyperlipidemia 1 , thioredoxin binding protein-2

GENE ID SPECIES
100195402 Salmo salar
446457 Xenopus laevis
10628 Homo sapiens
475829 Canis lupus familiaris
733688 Sus scrofa
506790 Bos taurus
56338 Mus musculus
117514 Rattus norvegicus
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