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Thioredoxin Interacting Protein Proteins (TXNIP)

regulates thioredoxin to play an important role in the preservation of cellular viability [RGD, Feb 2006].. Additionally we are shipping TXNIP Antibodies (85) and TXNIP Kits (29) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
TXNIP 10628 Q9H3M7
TXNIP 56338 Q8BG60
TXNIP 117514 Q5M7W1
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Top TXNIP Proteins at antibodies-online.com

Showing 9 out of 12 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Wheat germ Human GST tag 10 μg Log in to see 9 Days
$405.71
Details
Yeast Wild boar His tag   1 mg Log in to see 56 to 66 Days
$3,080.00
Details
Yeast Rat His tag   1 mg Log in to see 56 to 66 Days
$3,089.17
Details
Yeast Mouse His tag   50 μg Log in to see 8 to 11 Days
$341.00
Details
HOST_Escherichia coli (E. coli) Mouse GST tag,His tag   100 μg Log in to see 11 to 13 Days
$756.80
Details
HOST_Escherichia coli (E. coli) Human His tag   100 μg Log in to see 11 to 13 Days
$767.80
Details
HOST_Human Human Un-conjugated   20 μg Log in to see 9 to 11 Days
$785.40
Details

TXNIP Proteins by Origin and Source

Origin Expressed in Conjugate
Human , ,
,
Mouse (Murine) ,
,
Rat (Rattus)

More Proteins for Thioredoxin Interacting Protein (TXNIP) Interaction Partners

Human Thioredoxin Interacting Protein (TXNIP) interaction partners

  1. Heme oxygenase (show HMOX1 Proteins) rs2071749 polymorphism was positively associated with obesity in Mexicans.

  2. These data identify novel Txnip protein interactions.

  3. Glucose exerts strong stimulatory effects on activation histone marks while having inhibitory effects on repression marks in the promoter of the TXNIP gene, and this was associated with a marked increase in expression of the proinflammatory gene in kidney.

  4. No evidence that SNPS in TXNIP has effect, but the rs4485648 polymorphism of the TrxR2 (show TXNRD2 Proteins) gene might exert an independent effect on the development of Diabetic retinopathy.

  5. An association has been found between the TXNIP gene methylation pattern and type 2 diabetes mellitus in ischemic stroke patients through epigenetic mechanisms, related to sustained hyperglycemia levels with HbA1c >/= 7%.

  6. These findings thereby provide new mechanistic insight into the regulation of TXNIP and beta-cell biology and reveal novel links between proinflammatory cytokines, carbohydrate response element binding protein (show MLXIPL Proteins)-mediated transcription, and microRNA signaling.

  7. The crystal structure of the complex between a phosphorylated PPxY motif of TXNIP and the SH2 domain of Vav2 reveals a conserved recognition mechanism.

  8. Activation of the miR (show MLXIP Proteins)-373-TXNIP-HIF1alpha (show HIF1A Proteins)-TWIST signaling axis is correlated with a worse outcome in patients with breast cancer.

  9. Metformin down-regulates high-glucose-induced TXNIP transcription by inactivating ChREBP (show MLXIPL Proteins) and FOXO1 (show FOXO1 Proteins) in endothelial cells, partially through AMP-activated protein kinase (show PRKAA2 Proteins) activation

  10. Foam cell-released 4-hydroxnonenal activates PPARdelta (show PPARD Proteins) in Vascular endothelial cells, leading to increased TXNIP expression and consequently to senescence.

Pig (Porcine) Thioredoxin Interacting Protein (TXNIP) interaction partners

  1. The molecular characterization of porcine TXNIP gene, is described.

  2. single-marker and haplotype analyses revealed significant effects of TXNIP on hot carcass weight, test daily gain, and lifetime daily gain

Cow (Bovine) Thioredoxin Interacting Protein (TXNIP) interaction partners

  1. Foam cell-released 4-hydroxnonenal activates PPARdelta (show PPARD Proteins) in Vascular endothelial cells, leading to increased TXNIP expression and consequently to senescence.

Mouse (Murine) Thioredoxin Interacting Protein (TXNIP) interaction partners

  1. Glucose exerts strong stimulatory effects on activation histone marks while having inhibitory effects on repression marks in the promoter of the TXNIP gene, and this was associated with a marked increase in expression of the proinflammatory gene in kidney.

  2. Diabetes induces TXNIP expressions at mRNA levels, but shows the opposite effect on GS.

  3. ITCH targets TXNIP for ubiquitin-proteasome degradation in cardiomyocytes and ameliorates reactive oxygen species-induced cardiotoxicity through the thioredoxin (show TXN Proteins) system.

  4. These findings thereby provide new mechanistic insight into the regulation of TXNIP and beta-cell biology and reveal novel links between proinflammatory cytokines, carbohydrate response element binding protein (show MLXIPL Proteins)-mediated transcription, and microRNA signaling.

  5. Txnip plays an important role in oxidative inflammatory response and atherosclerotic lesion development in ApoE (show APOE Proteins) knockout mice.

  6. The results indicate that a lack of TxNIP protects against diabetic nephropathy (DN) and support in vitro data that upregulation of TxNIP by glucose is a key mediator of early oxidative stress and a trigger for the development and progression of DN.

  7. Reactive oxygen species regulation through REDD1 (show DDIT4 Proteins)/TXNIP is physiological rheostat controlling stress-induced autophagy.

  8. These findings suggest that TXNIP is required for endothelial cell survival and homeostasis especially under stress conditions including hyperoxia.

  9. HG-induced NADPH oxidase (show NOX1 Proteins) activation is driven by TXNIP which subsequently triggers NALP3 (show NLRP3 Proteins) inflammasome activation in podocytes and ultimately led to podocyte injury

  10. Data indicate that thioredoxin-interacting protein (TXNIP)levels are induced in erythroid differentiation.

TXNIP Protein Profile

Protein Summary

regulates thioredoxin to play an important role in the preservation of cellular viability

Gene names and symbols associated with TXNIP

  • thioredoxin interacting protein (txnip)
  • thioredoxin interacting protein (TXNIP)
  • thioredoxin interacting protein (Txnip)
  • 1200008J08Rik protein
  • AA682105 protein
  • EST01027 protein
  • HHCPA78 protein
  • Hyplip1 protein
  • Tbp-2 protein
  • THIF protein
  • Vdup1 protein

Protein level used designations for TXNIP

thioredoxin interacting protein , Thioredoxin-interacting protein , thioredoxin binding protein 2 , thioredoxin-binding protein 2 , thioredoxin-interacting protein , upregulated by 1,25-dihydroxyvitamin D-3 , vitamin D3 up-regulated protein 1 , hyperlipidemia 1 , thioredoxin binding protein-2

GENE ID SPECIES
100195402 Salmo salar
446457 Xenopus laevis
10628 Homo sapiens
475829 Canis lupus familiaris
733688 Sus scrofa
506790 Bos taurus
56338 Mus musculus
117514 Rattus norvegicus
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