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Thioredoxin Reductase 1 (TXNRD1) ELISA Kits

TXNRD1 encodes a member of the family of pyridine nucleotide oxidoreductases. Additionally we are shipping TXNRD1 Antibodies (99) and TXNRD1 Proteins (30) and many more products for this protein.

list all ELISA KIts Gene Name GeneID UniProt
TXNRD1 7296 Q16881
TXNRD1 58819 O89049
TXNRD1 50493 Q9JMH6
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Top TXNRD1 ELISA Kits at

Showing 10 out of 27 products:

Catalog No. Reactivity Sensitivity Range Images Quantity Supplier Delivery Price Details
Mouse 0.059 ng/mL 15.63-1000 pg/mL 96 Tests Log in to see 9 to 11 Days
Human 0.135 ng/mL 0.31-20 ng/mL 96 Tests Log in to see 9 to 11 Days
Cow 0.078 0.312   96 Tests Log in to see 11 to 13 Days
Rat 0.078 0.312   96 Tests Log in to see 11 to 13 Days
Human 15.05 pg/mL 41.15-30000 pg/mL   96 Tests Log in to see 9 to 11 Days
  96 Tests Log in to see 8 to 9 Days
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Guinea Pig
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More ELISA Kits for TXNRD1 Interaction Partners

Arabidopsis thaliana Thioredoxin Reductase 1 (TXNRD1) interaction partners

  1. An Arabidopsis thaliana double knockout mutant lacking NTRC and Srx (show SRX1 ELISA Kits) shows a phenotype similar to the ntrc mutant, while the srx (show SRX1 ELISA Kits) mutant resembles wild-type plants. NTRC deficiency causes reduced overoxidation of 2-Cys (show DNAJC5 ELISA Kits) peroxiredoxins.

  2. NADPH thioredoxin reductase C is involved in redox regulation of the Mg-chelatase I subunit in Arabidopsis thaliana chloroplasts

  3. interaction of chloroplast 2-Cys (show DNAJC5 ELISA Kits) peroxiredoxin with NADPH (show NQO1 ELISA Kits)-thioredoxin reductase C (NTRC) and thioredoxin (show TXN ELISA Kits) x

  4. The strongest reduction in ntrc growth occurred under photoperiods with nights longer than 14 h, whereas knockout of the NTRC gene did not alter the circadian-clock-controlled growth. Lack of NTRC modulated chloroplast reactive oxygen species metabolism.

  5. heat shock-mediated holdase chaperone function of NTRC is responsible for the increased thermotolerance of Arabidopsis and the activity is significantly supported by NADPH (show NQO1 ELISA Kits)

  6. analysis of electron transfer pathways and dynamics of chloroplast NADPH-dependent thioredoxin reductase C (NTRC)

  7. NADPH (show NQO1 ELISA Kits)-thioredoxin reductase C (NTRC), previously reported as exclusive to green tissues, is also expressed in nonphotosynthetic tissues of Arabidopsis thaliana.

  8. ANTR-C functions as an electron donor for plastidial 2-Cys (show DNAJC5 ELISA Kits) peroxiredoxins and represents the NADPH (show NQO1 ELISA Kits)-dependent thioredoxin/thioredoxin (show TXN ELISA Kits) reductase system in chloroplasts. [ANTR-C]

  9. NTRC and 2-Cys (show DNAJC5 ELISA Kits) Prx (show PRX ELISA Kits) are involved in the protection of at least the later part of the chlorophyll biosynthetic pathway; NTRC and 2-Cys (show DNAJC5 ELISA Kits) Prx (show PRX ELISA Kits) in vitro stimulate the aerobic cyclase step of this pathway.

  10. Chloroplast NADPH (show NQO1 ELISA Kits)-thioredoxin reductase, NTRC, regulates several key processes, including chlorophyll biosynthesis and the shikimate pathway, in chloroplasts. [NTRC]

Caenorhabditis elegans (C. elegans) Thioredoxin Reductase 1 (TXNRD1) interaction partners

  1. Selenoprotein TRXR-1 and GSR-1 (show GSR ELISA Kits) are essential for removal of old cuticle during molting in Caenorhabditis elegans.

Human Thioredoxin Reductase 1 (TXNRD1) interaction partners

  1. TXNRD1_v1 and TXNRD1_v2 have distinct roles in differentiation, possibly by altering the expression of the genes associated with differentiation, and further emphasize the importance in distinguishing each unique action of different TrxR1 splice forms

  2. Tissue microarrays containing human nevi and melanomas were used to evaluate levels of the antioxidant protein (show PRDX3 ELISA Kits) thioredoxin reductase 1 (TR1), which was found to increase as a function of disease progression.

  3. Rheumatoid arthritis patients with high disease activity had significantly elevated TrxR levels in plasma and synovial fluid than did those with low disease activity.

  4. TRX-1 (show MLL ELISA Kits)/PRX-1 (show PRDX1 ELISA Kits) levels are associated with NADPH oxidase (show NOX1 ELISA Kits)-activity in vivo and in vitro in atherosclerosis.

  5. The association of TXNRD1 variability was found with physical performance, with three variants (rs4445711, rs1128446, and rs11111979) associated with physical functioning after 85 years of age.

  6. In gene-based analysis of Se metabolism and selenoprotein candidate genes, only thioredoxin reductase 1 (TXNRD1) was significantly associated with toenail Selenium levels. [meta-analysis]

  7. Expression of TrxR1 correlated highly with both the astrocytoma grade and proliferative index

  8. Se/S-palmitoylation acts as an important modulator of TrxR1/hTrx1 (show MLL ELISA Kits) activities

  9. Thioredoxin reductase activity may be more important than GSH level in protecting human lens epithelial cells against UVA light.

  10. Thioredoxin reductase 1 (TrxR1) protein levels and activity were inducible up to 2.2-fold by selenium.

Pig (Porcine) Thioredoxin Reductase 1 (TXNRD1) interaction partners

  1. The developmental expression of cytosolic glutathione peroxidase (show GPX1 ELISA Kits) and TRXR1 during fetal development and the effect of maternal selenium consumption on the expression of these proteins are reported.

  2. regenerated coronary endothelial cells exhibit downregulation of thioredoxin reductase

Cow (Bovine) Thioredoxin Reductase 1 (TXNRD1) interaction partners

  1. These results suggest that thioredoxin reductase (show PRDX5 ELISA Kits) may act as a positive regulator of NF-kappa B (show NFKB1 ELISA Kits) and may play an important role in the cellular inflammatory response.

  2. data provide evidence for the involvement of the Trx/TrxR (show GSR ELISA Kits) system, in the regulation of haem oxygenase-1 expression in aortic endothelial cells during pro-oxidant challenge

Mouse (Murine) Thioredoxin Reductase 1 (TXNRD1) interaction partners

  1. the timely upregulation of Trx1 (show TXN ELISA Kits)/TrxR1 and the active control of intracellular redox status is critical for the survival of thymocytes during and short after positive selection.

  2. Considering the variable expression levels of Sep15 and TR1 found within the human population, our results provide insights into new roles of selenoproteins in cancer

  3. Data suggest TXNRD1 and TXRNRD2 function at the top of a redox pyramid that governs the oxidation state of peroxiredoxins and other protein factors, thereby dictating a hierarchy of phenotypic responses to oxidative insults.

  4. Augmentation of GSH systems by TrxR1 inhibition could represent a promising therapeutic approach to attenuate oxidant-mediated lung injury and improve patient outcomes.

  5. Because the N-terminal domain of Sepp1 (show SEPP1 ELISA Kits) has a thioredoxin (show TXN ELISA Kits) fold, Sepp1 (show SEPP1 ELISA Kits)(UF) were compared with full-length Sepp1 (show SEPP1 ELISA Kits), Sepp1 (show SEPP1 ELISA Kits)(Delta240-361), and Sepp1 (show SEPP1 ELISA Kits)(U40S) as a substrate of thioredoxin reductase-1 (TrxR1).

  6. Sec-containing TrxR1 is absolutely required for self-sufficient growth of MEFs under high-glucose conditions, owing to an essential importance of this enzyme for elimination of glucose-derived H2O2.

  7. The exaggerated TrxR release to serum upon liver injury may reflect more complex events than a mere passive release of hepatic enzymes to the extracellular milieu.

  8. TrxR1-deficient cells are more sensitive to TNF-alpha (show TNF ELISA Kits) induced apoptosis than control cells.

  9. Txnrd1-null livers did not have more effective gene expression responses to APAP challenge; however, their constitutive metabolic state supported more robust GSH biosynthesis, glutathionylation, and glucuronidation systems

  10. TR1 protects against chemically induced hepatocarcinogenesis via the control of the cellular redox state, whereas its role in promoting this type of cancer is minimal

TXNRD1 Antigen Profile

Antigen Summary

This gene encodes a member of the family of pyridine nucleotide oxidoreductases. This protein reduces thioredoxins as well as other substrates, and plays a role in selenium metabolism and protection against oxidative stress. The functional enzyme is thought to be a homodimer which uses FAD as a cofactor. Each subunit contains a selenocysteine (Sec) residue which is required for catalytic activity. The selenocysteine is encoded by the UGA codon that normally signals translation termination. The 3' UTR of selenocysteine-containing genes have a common stem-loop structure, the sec insertion sequence (SECIS), that is necessary for the recognition of UGA as a Sec codon rather than as a stop signal. Alternative splicing results in several transcript variants encoding the same or different isoforms.

Gene names and symbols associated with TXNRD1

  • thioredoxin reductase 1 (TXNRD1) antibody
  • thioredoxin reductase 1 (txnrd1) antibody
  • thioredoxin reductase 1 (Trxr-1) antibody
  • NADPH-dependent thioredoxin reductase C (NTRC) antibody
  • Protein TRXR-1 (trxr-1) antibody
  • thioredoxin reductase 1 (Txnrd1) antibody
  • cb682 antibody
  • fb83a08 antibody
  • GB14972 antibody
  • GRIM-12 antibody
  • MGC85342 antibody
  • NADPH-dependent thioredoxin reductase C antibody
  • T32G6.20 antibody
  • T32G6_20 antibody
  • Tr antibody
  • TR1 antibody
  • TRXR1 antibody
  • TXNR antibody
  • wu:fb83a08 antibody

Protein level used designations for TXNRD1

thioredoxin reductase 1, cytoplasmic , thioredoxin reductase 3 , thioredoxin reductase 1 , thioredoxin reductase 1, cytoplasmic-like , KM-102-derived reductase-like factor , gene associated with retinoic and IFN-induced mortality 12 protein , gene associated with retinoic and interferon-induced mortality 12 protein , oxidoreductase , thioredoxin reductase GRIM-12 , thioredoxin reductase TR1 , TR , redox enzyme thioredoxin reductase , NADPH-dependent thioredoxin reductase , selenoprotein oxidoreductase , TR alpha

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352924 Danio rerio
410032 Apis mellifera
447610 Xenopus laevis
467112 Pan troglodytes
100015072 Monodelphis domestica
100401029 Callithrix jacchus
100479058 Ailuropoda melanoleuca
100495372 Xenopus (Silurana) tropicalis
100568111 Anolis carolinensis
100600391 Nomascus leucogenys
818766 Arabidopsis thaliana
177466 Caenorhabditis elegans
7296 Homo sapiens
396681 Sus scrofa
58819 Rattus norvegicus
474536 Canis lupus familiaris
282388 Bos taurus
50493 Mus musculus
418082 Gallus gallus
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100174180 Pongo abelii
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