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Thrombomodulin Proteins (THBD)

The protein encoded by this intronless gene is an endothelial-specific type I membrane receptor that binds thrombin. Additionally we are shipping Thrombomodulin Antibodies (250) and Thrombomodulin Kits (82) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
THBD 7056 P07204
THBD 21824 P15306
THBD 83580  
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Top Thrombomodulin Proteins at antibodies-online.com

Showing 10 out of 23 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
Insect Cells Mouse rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.25 mg Log in to see 49 to 54 Days
$4,244.78
Details
Insect Cells Human rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.5 mg Log in to see 49 to 54 Days
$6,041.49
Details
HOST_Escherichia coli (E. coli) Rabbit His tag 50 μg Log in to see 9 to 11 Days
$484.00
Details
HOST_HEK-293 Cells Human Un-conjugated   50 μg Log in to see 2 to 3 Days
$808.50
Details
HOST_Human Cells Rat His tag 10 μg Log in to see 20 to 21 Days
$250.80
Details
HOST_Escherichia coli (E. coli) Human GST tag,His tag   100 μg Log in to see 9 Days
$630.00
Details
HOST_Escherichia coli (E. coli) Human Un-conjugated 100 μg Log in to see 11 to 13 Days
$844.80
Details
Yeast Cow His tag   1 mg Log in to see 56 to 66 Days
$2,784.83
Details
Yeast Primates His tag   1 mg Log in to see 56 to 66 Days
$3,408.17
Details
HOST_HEK-293 Human Un-conjugated   0.002 mg Log in to see 2 to 3 Days
$178.75
Details

THBD Proteins by Origin and Source

Origin Expressed in Conjugate
Human , , , ,
, ,
Mouse (Murine) ,
,
Rat (Rattus) ,

More Proteins for Thrombomodulin (THBD) Interaction Partners

Human Thrombomodulin (THBD) interaction partners

  1. The results demonstrate that the LFA-1 (show ITGAL Proteins) and Mac-1 (show ITGAM Proteins) integrins on leukocytes bind to thrombomodulin (TM), thereby establishing the molecular and structural basis underlying LFA-1 (show ITGAL Proteins) and Mac-1 (show ITGAM Proteins) integrin interaction with TM on endothelial cells.

  2. Human thrombomodulin transgenic aortic endothelial cells are less sensitive to activation by either HMGB1 or hTNFalpha, an effect that appears to be dependent on the lectin-like domain of TBM.

  3. In placenta of patients with preeclampsia, we detected abnormal expression of F3 and THBD with increased protein and mRNA levels. The role of these molecules in the pathogenesis of this disease and in alterations of hemostatic and histopathological aspects of placentas need further studying.

  4. TM up-regulated E-cadherin (show CDH1 Proteins) but down-regulated N-cadherin (show CDH2 Proteins) expression, resulting in reversal of epithelial-mesenchymal transition (EMT (show ITK Proteins)) in the lung cancer cells.

  5. High serum thrombomodulin expression is associated with non-alcoholic fatty liver disease.

  6. results do not suggest a predictive role for THBD c.1418C>T polymorphism in VTE recurrence

  7. R12 (show GPR17 Proteins) is a critical residue for the activation of TAFI (show CPB2 Proteins) by thrombin (show F2 Proteins)-thrombomodulin

  8. Study detected a statistically significant positive correlation between expanded disability status scale scores and thrombomodulin levels (p<0.01) and a 10% positive correlation between expanded disability status scale scores and APC (show APC Proteins) levels in multiple sclerosis patients

  9. Case Report: thrombotic microangiopathy with mutations in complement factor I (show CFI Proteins) and thrombomodulin.

  10. increased plasma TM levels and serum hs-CRP (show CRP Proteins) levels in cerebral infarction (CI) patients were associated with the development of CI in Asians.

Mouse (Murine) Thrombomodulin (THBD) interaction partners

  1. the lectin-like domain of thrombomodulin is critically involved in host defence against E. coli induced acute pyelonephritis

  2. Identified Nur77 (show NR4A1 Proteins)/Nor1 (show NR4A3 Proteins) as novel regulators of thrombomodulin expression and function in vascular endothelial cells.

  3. TM expression in corneal epithelium was modulated during the corneal wound healing process, and may be regulated by PDGF (show PDGFA Proteins)-BB. In addition, rTMD23 has therapeutic potential in corneal injury

  4. Thrombomodulin contributes to gamma tocotrienol-mediated lethality protection and hematopoietic cell recovery in irradiated mice

  5. the recombinant epidermal growth factor (show EGF Proteins)-like domain plus serine/threonine-rich domain of thrombomodulin suppresses the inflammatory response in mice

  6. Thrombomodulin may modulate allergic responses by inhibiting the activation of both eosinophils and mast cells.

  7. Thrombomodulin modulates dendritic cells via both antagonism of high mobility group protein B1 (show HMGB1 Proteins) and an independent mechanism.

  8. The lectin-like domain of TM does not play an important role in the host response to M. tuberculosis infection in mice.

  9. Recombinant thrombomodulin protects mice against histone-induced lethal thromboembolism.

  10. TM's lectin-like domain constrains glucose-induced complement activation on endothelial cells and podocytes and ameliorates albuminuria and glomerular damage.

Rabbit Thrombomodulin (THBD) interaction partners

  1. Atorvastin induces THBD expression in the aorta of cholesterol-fed rabbits.

Thrombomodulin (THBD) Protein Profile

Protein Summary

The protein encoded by this intronless gene is an endothelial-specific type I membrane receptor that binds thrombin. This binding results in the activation of protein C, which degrades clotting factors Va and VIIIa and reduces the amount of thrombin generated. Mutations in this gene are a cause of thromboembolic disease, also known as inherited thrombophilia.

Gene names and symbols associated with Thrombomodulin Proteins (THBD)

  • thrombomodulin (THBD)
  • thrombomodulin (Thbd)
  • AHUS6 protein
  • AI385582 protein
  • BDCA3 protein
  • CD141 protein
  • THBD protein
  • THPH12 protein
  • THRM protein
  • TM protein

Protein level used designations for Thrombomodulin Proteins (THBD)

thrombomodulin , CD141 antigen , fetomodulin , snoRNA MBII-339 , thrombomdulin , TM

GENE ID SPECIES
469898 Pan troglodytes
702132 Macaca mulatta
100049012 Felis catus
7056 Homo sapiens
474355 Canis lupus familiaris
21824 Mus musculus
83580 Rattus norvegicus
100157642 Sus scrofa
100008887 Oryctolagus cuniculus
100723479 Cavia porcellus
281529 Bos taurus
428546 Gallus gallus
101103256 Ovis aries
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