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The protein encoded by THSD1 contains a type 1 thrombospondin domain, which is found in a number of proteins involved in the complement pathway, as well as in extracellular matrix proteins. Additionally we are shipping THSD1 Antibodies (29) and THSD1 Proteins (12) and many more products for this protein.
The THSD1 gene may play a role in the tumorigenesis of colorectal cancer
Thrombospondin has a role in inducing RhoA (show RHOA ELISA Kits) inactivation through FAK (show PTK2 ELISA Kits)-dependent signaling to stimulate focal adhesion disassembly
The strong immunolocalization of thrombospondin (TSP (show THBS1 ELISA Kits)) in the outer anulus of the intervertebral disc indicates a role for TSP (show THBS1 ELISA Kits) in the avascular status of the adult human disc.
These findings suggest that THSD1 is a good candidate tumor suppressor gene.
The protein encoded by this gene contains a type 1 thrombospondin domain, which is found in a number of proteins involved in the complement pathway, as well as in extracellular matrix proteins. Alternatively spliced transcript variants encoding different isoforms have been observed for this gene.
thrombospondin type-1 domain-containing protein 1
, transmembrane molecule with thrombospondin module
, thrombospondin, type I, domain 1
, thrombospondin type I domain-containing 1