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The protein encoded by THSD1 contains a type 1 thrombospondin domain, which is found in a number of proteins involved in the complement pathway, as well as in extracellular matrix proteins. Additionally we are shipping THSD1 Antibodies (71) and many more products for this protein.
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Human THSD1 Protein expressed in HEK-293 Cells - ABIN2181813
Clark, Burke, Volkin, Offit, Ward, Bresee, Dennehy, Gooch, Malacaman, Matson, Walter, Watson, Krah, Dallas, Schödel, Kaplan, Heaton: Safety, immunogenicity and efficacy in healthy infants of G1 and G2 human reassortant rotavirus vaccine in a new stabilizer/buffer liquid formulation. in The Pediatric infectious disease journal 2003
Show all 2 references for ABIN2181813
The THSD1 gene may play a role in the tumorigenesis of colorectal cancer
Thrombospondin has a role in inducing RhoA (show RHOA Proteins) inactivation through FAK (show PTK2 Proteins)-dependent signaling to stimulate focal adhesion disassembly
The strong immunolocalization of thrombospondin (TSP (show THBS1 Proteins)) in the outer anulus of the intervertebral disc indicates a role for TSP (show THBS1 Proteins) in the avascular status of the adult human disc.
These findings suggest that THSD1 is a good candidate tumor suppressor gene.
The protein encoded by this gene contains a type 1 thrombospondin domain, which is found in a number of proteins involved in the complement pathway, as well as in extracellular matrix proteins. Alternatively spliced transcript variants encoding different isoforms have been observed for this gene.
thrombospondin type-1 domain-containing protein 1
, transmembrane molecule with thrombospondin module
, thrombospondin, type I, domain 1
, thrombospondin type I domain-containing 1