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Thrombospondin, Type I, Domain Containing 4 Proteins (THSD4)

Promotes FBN1 matrix assembly. Additionally we are shipping Thrombospondin, Type I, Domain Containing 4 Kits (1) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
THSD4 79875 Q6ZMP0
THSD4 207596 Q3UTY6
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Top Thrombospondin, Type I, Domain Containing 4 Proteins at antibodies-online.com

Showing 3 out of 3 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 39 to 44 Days
$9,248.02
Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 39 to 44 Days
$9,248.02
Details
HOST_Wheat germ Human GST tag 10 μg Log in to see 9 Days
$405.71
Details

THSD4 Proteins by Origin and Source

Origin Expressed in Conjugate
Human ,
,
Mouse (Murine)

More Proteins for Thrombospondin, Type I, Domain Containing 4 (THSD4) Interaction Partners

Human Thrombospondin, Type I, Domain Containing 4 (THSD4) interaction partners

  1. In breast cancer, some GATA3 (show GATA3 Proteins) effects shift from tumor suppressing to tumor promoting during tumorigenesis, with deregulation of three genes, BCL2 (show BCL2 Proteins), DACH1 (show DACH1 Proteins), THSD4, representing major GATA3 (show GATA3 Proteins)-controlled processes in cancer progression.

  2. ADAMTSL6beta has a role in fibrillin-1 (show FBN1 Proteins) microfibril formation

  3. THSD4 polymorphism was not found to be associated with COPD (show ARCN1 Proteins) risk

  4. Data show expression of TNS1, GSTCD, AGER (show AGER Proteins), HTR4 (show HTR4 Proteins) and THSD4 in lung tissue and indicate potential targets for interventions to alleviate respiratory disease.

Mouse (Murine) Thrombospondin, Type I, Domain Containing 4 (THSD4) interaction partners

  1. ADAMTSL6beta has a role in fibrillin-1 (show FBN1 Proteins) microfibril formation

  2. Results indicated that ADAMTSL-6 is a novel microfibril-associated protein that binds directly to fibrillin-1 (show FBN1 Proteins) and promotes fibrillin-1 (show FBN1 Proteins) matrix assembly.

Thrombospondin, Type I, Domain Containing 4 (THSD4) Protein Profile

Protein Summary

Promotes FBN1 matrix assembly. Attenuates TGFB signaling, possibly by accelerating the sequestration of large latent complexes of TGFB or active TGFB by FBN1 microfibril assembly, thereby negatively regulating the expression of TGFB regulatory targets, such as POSTN.

Gene names and symbols associated with THSD4

  • thrombospondin, type I, domain containing 4 (THSD4)
  • thrombospondin, type I, domain containing 4 (Thsd4)
  • ADAMTSL-6 protein
  • Adamtsl4 protein
  • ADAMTSL6 protein
  • AI585901 protein
  • B230114P05Rik protein
  • FVSY9334 protein
  • PRO34005 protein

Protein level used designations for THSD4

A disintegrin and metalloproteinase with thrombospondin motifs-like protein 6 , ADAMTS-like protein 6 , thrombospondin type-1 domain-containing protein 4 , ADAMTS-like protein 4 , ADAMTSL-4

GENE ID SPECIES
79875 Homo sapiens
207596 Mus musculus
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