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The protein encoded by THBS1 contains a type 1 thrombospondin domain, which is found in a number of proteins involved in the complement pathway, as well as in extracellular matrix proteins. Additionally we are shipping Thrombospondin I Antibodies (25) and many more products for this protein.
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The THSD1 (show THSD1 Proteins) gene may play a role in the tumorigenesis of colorectal cancer
Thrombospondin has a role in inducing RhoA (show RHOA Proteins) inactivation through FAK (show PTK2 Proteins)-dependent signaling to stimulate focal adhesion disassembly
The strong immunolocalization of thrombospondin (TSP) in the outer anulus of the intervertebral disc indicates a role for TSP in the avascular status of the adult human disc.
These findings suggest that THSD1 (show THSD1 Proteins) is a good candidate tumor suppressor gene.
The protein encoded by this gene contains a type 1 thrombospondin domain, which is found in a number of proteins involved in the complement pathway, as well as in extracellular matrix proteins. Alternatively spliced transcript variants encoding different isoforms have been observed for this gene.
, thrombospondin type-1 domain-containing protein 1
, thrombospondin, type I, domain 1
, transmembrane molecule with thrombospondin module