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TSLP encodes a hemopoietic cytokine proposed to signal through a heterodimeric receptor complex composed of the thymic stromal lymphopoietin receptor and the IL-7R alpha chain. Additionally we are shipping Thymic Stromal Lymphopoietin Kits (66) and Thymic Stromal Lymphopoietin Proteins (39) and many more products for this protein.
Showing 10 out of 181 products:
Human Polyclonal TSLP Primary Antibody for ELISA (Capture), WB - ABIN2665475
Mazzucchelli, Hixon, Spolski, Chen, Li, Hall, Willette-Brown, Hurwitz, Leonard, Durum: Development of regulatory T cells requires IL-7Ralpha stimulation by IL-7 or TSLP. in Blood 2008
Show all 8 references for ABIN2665475
Human Polyclonal TSLP Primary Antibody for ELISA (Detection) - ABIN2660798
Nguyen, Vanichsarn, Nadeau: TSLP directly impairs pulmonary Treg function: association with aberrant tolerogenic immunity in asthmatic airway. in Allergy, asthma, and clinical immunology : official journal of the Canadian Society of Allergy and Clinical Immunology 2010
Show all 7 references for ABIN2660798
Human Polyclonal TSLP Primary Antibody for ELISA, ICC - ABIN258390
Levin, Koelling, Friend, Isaksen, Ziegler, Perlmutter, Farr: Thymic stromal lymphopoietin: a cytokine that promotes the development of IgM+ B cells in vitro and signals via a novel mechanism. in Journal of immunology (Baltimore, Md. : 1950) 1999
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Human Polyclonal TSLP Primary Antibody for EIA, WB - ABIN955356
Angelova-Fischer, Fernandez, Donnadieu, Bulfone-Paus, Zillikens, Fischer, Soumelis: Injury to the stratum corneum induces in vivo expression of human thymic stromal lymphopoietin in the epidermis. in The Journal of investigative dermatology 2010
Show all 4 references for ABIN955356
Human Polyclonal TSLP Primary Antibody for EIA, IHC (p) - ABIN501079
Ziegler, Liu: Thymic stromal lymphopoietin in normal and pathogenic T cell development and function. in Nature immunology 2006
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Human Polyclonal TSLP Primary Antibody for EIA, IHC (p) - ABIN501077
Quentmeier, Drexler, Fleckenstein, Zaborski, Armstrong, Sims, Lyman: Cloning of human thymic stromal lymphopoietin (TSLP) and signaling mechanisms leading to proliferation. in Leukemia 2001
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Human Polyclonal TSLP Primary Antibody for IHC (p), IHC - ABIN258389
Sims, Williams, Morrissey, Garka, Foxworthe, Price, Friend, Farr, Bedell, Jenkins, Copeland, Grabstein, Paxton: Molecular cloning and biological characterization of a novel murine lymphoid growth factor. in The Journal of experimental medicine 2000
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Results showed that TSLP promoted the production of alpha-SMA (show SMN1 Antibodies) and collagen I (P<0.001), suggesting that it can accelerate MRC-5 cell fibrosis.
Chronic rhinosinusitis with nasal polyps (CRSwNP) epithelial cells release TSLP and IL-25 (show IL25 Antibodies) when stimulated by poly(I:C) but not by DP or AF, suggesting that viral infection may contribute to maintain and amplify the T2 immune response seen in CRSwNP.
TSLP is a key mediator in the pathogenesis of inflammatory bowel diseases and that further studies are needed to evaluate its role. [review]
Letter: report decreased salivary gland TSLP expression in primary Sjogren's syndrome.
A novel mouse xenograft model to study the role of TSLP-induced CRLF2 (show CRLF2 Antibodies) signals in normal and malignant human B lymphopoiesis has been developed.
Increased induction and expression of TSLP, IL-25 (show IL25 Antibodies), and IL-33 (show IL33 Antibodies) from nasal epithelial cells contribute to the pathophysiology of eosinophilic chronic rhinosinusitis.
Heat stress-induced HSPs can significantly reduce the production and secretion of TSLP from keratinocytes cultured under Th2 environment.
TSLP expression in the skin is mediated via RARgamma-RXR pathways.
Epidermal thymic stromal lymphopoietin predicts the development of atopic dermatitis during infancy.
study shows that specific food antigens can trigger innate immune mediated esophageal TSLP secretion
TNF-alpha (show TNF Antibodies) and IL-1beta (show IL1B Antibodies), which are partly produced by LPS (show TLR4 Antibodies)-activated leukocytes, contribute to TSLP production via TLR4 (show TLR4 Antibodies) activation in vivo.
IL-33 (show IL33 Antibodies)-ERK (show EPHB2 Antibodies)/JNK (show MAPK8 Antibodies)/p38 (show CRK Antibodies)/Egr-1 (show EGR1 Antibodies)/TSLP axis involved in allergic skin Th2 inflammation
Suggest that TSLP may be involved in acute lung injury, and blockage of TSLP signaling using TSLPR (show CRLF2 Antibodies)-Ig improves ALI at least in part by regulation of dendritic cell functions.
results highlight a previously unappreciated function of the immune system in controlling the early development of cancer and establish a fundamental role for TSLP and Th2 cells in tumor immunity against early-stage cancers.
Thymic stromal lymphopoietin-induced interleukin-17A is involved in the development of IgE-mediated atopic dermatitis-like skin lesions in mice
production by monocyte-derived dendritic cells requires the integration of signals from dectin-1 (show CLEC7A Antibodies), the IL-1 (show IL1A Antibodies) receptor, and endoplasmic reticulum stress response stress signaling pathways
Rhinovirus infection interferes with induction of tolerance to aeroantigens through OX40 ligand (show TNFSF4 Antibodies), thymic stromal lymphopoietin, and IL-33 (show IL33 Antibodies)
LIGHT controls TSLP to drive pulmonary fibrosis.
There were no significant differences in clinical scores and numbers of infiltrating eosinophils among IL-25KO, TSLPR (show CRLF2 Antibodies) KO, and wild-type mice.
This gene encodes a hemopoietic cytokine proposed to signal through a heterodimeric receptor complex composed of the thymic stromal lymphopoietin receptor and the IL-7R alpha chain. It mainly impacts myeloid cells and induces the release of T cell-attracting chemokines from monocytes and enhances the maturation of CD11c(+) dendritic cells. The protein promotes T helper type 2 (TH2) cell responses that are associated with immunity in various inflammatory diseases, including asthma, allergic inflammation and chronic obstructive pulmonary disease. The protein is therefore considered a potential therapeutic target for the treatment of such diseases. Alternative splicing of this gene results in multiple transcript variants.
thymic stromal lymphopoietin
, thymic stromal lymphopoetin
, thymic stroma-derived lymphopoietin