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Plays an important role in the organization of the cytoskeleton. Additionally we are shipping TMSB4X Proteins (5) and TMSB4X Kits (4) and many more products for this protein.
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Increased Tb4 expression was observed in ethanol treated microglia. Knockdown of Tb4 enhanced ethanol-induced inflammatory mediators tumor necrosis factor-alpha and interleukin-1beta and nitric oxide in BV-2 cells was performed.
Results provide evidence that Tbeta4 regulate the levels of VEGF (show VEGFA Antibodies) and MMP-2 (show MMP2 Antibodies) via the Wnt (show WNT2 Antibodies)/beta-catenin (show CTNNB1 Antibodies)/Lef-1 (show LEF1 Antibodies) signaling pathway to influence the growth of blood vessels around hair follicles and to activate cell migration.
this study demonstrated, for the first time, that Tbeta4 was down-regulated in ROS (show ROS1 Antibodies)-stimulated PDLCs as well as Tbeta4 activation exhibited anti-inflammatory effects and anti-osteoclastogenesis in vitro.
Tbeta4 appears to regulate P38/ERK (show MAPK1 Antibodies)/AKT (show AKT1 Antibodies) signaling via its effect on VEGF (show VEGFA Antibodies) expression, with a resultant effect on the speed of hair growth, the pattern of HFs and the number of hair shafts
This study provides putative information concerning the signaling pathway through which Tb4 induces RUNX2 (show RUNX2 Antibodies) expression, which may help to understand the regulation of tooth development and tooth regeneration.
Tbeta4 substantially inhibited bleomycin-induced IL-17 (show IL17A Antibodies) over-expression in the lung tissue: a decreased amount of IL17 (show IL17A Antibodies)-producing cells and inhibited IL-17 (show IL17A Antibodies) expression in lung with Tbeta4 treatment correlate with its anti-inflammatory and anti-fibrotic effects.
These data suggest that Tbeta4 suppresses the TLR proinflammatory pathway by up-regulating miR (show MLXIP Antibodies)-146a.
Thymosin beta4 may play a role in aging-related hearing loss.
These data show that thymosinbeta4 and beta-actin are over-expressed during nurse cell formation upon T. spiralis infection and may be involved in nurse cell formation along with other actin-binding proteins.
Thymosin beta4 is a novel endothelial secreted trophic factor that functions synergistically with TGFbeta (show TGFB1 Antibodies) to regulate mural cell development and vascular wall stability.
Plays an important role in the organization of the cytoskeleton. Binds to and sequesters actin monomers (G actin) and therefore inhibits actin polymerization. Seraspenide inhibits the entry of hematopoietic pluripotent stem cells into the S-phase (By similarity).
prothymosin beta 4
, t beta 4
, thymosin beta-4