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Thyroid Stimulating Hormone Receptor Proteins (TSHR)

The protein encoded by TSHR is a membrane protein and a major controller of thyroid cell metabolism. Additionally we are shipping TSH receptor Antibodies (184) and TSH receptor Kits (19) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
TSHR 7253 P16473
TSHR 22095 P47750
Rat TSHR TSHR 25360 P21463
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Top TSH receptor Proteins at antibodies-online.com

Showing 10 out of 12 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
Insect Cells Mouse rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.25 mg Log in to see 59 to 64 Days
$6,052.17
Details
Insect Cells Human rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.5 mg Log in to see 59 to 64 Days
$8,623.45
Details
HOST_Escherichia coli (E. coli) Human His tag 50 μg Log in to see 21 to 26 Days
$341.00
Details
Yeast Human His tag 50 μg Log in to see 31 to 36 Days
$341.00
Details
HOST_Wheat germ Human Un-conjugated   10 μg Log in to see 9 Days
$641.43
Details
HOST_Escherichia coli (E. coli) Human Un-conjugated   100 μg Log in to see 9 to 14 Days
$558.62
Details
HOST_Escherichia coli (E. coli) Human Un-conjugated   100 μg Log in to see 9 to 14 Days
$810.39
Details
HOST_Escherichia coli (E. coli) Human Un-conjugated   50 μg Log in to see 16 to 21 Days
$314.29
Details

TSHR Proteins by Origin and Source

Origin Expressed in Conjugate
Human , , , ,
,
Mouse (Murine) ,
,

Top referenced TSH receptor Proteins

  1. Human TSH receptor Protein expressed in Wheat germ - ABIN1330596 : Nagata, Nakayama, Higaki, Ochi, Kanai, Matsushita, Kuwamoto, Kato, Murakami, Iwasaki, Nanba, Kimura, Hayashi: Reactivation of persistent Epstein-Barr virus (EBV) causes secretion of thyrotropin receptor antibodies (TRAbs) in EBV-infected B lymphocytes with TRAbs on their surface. in Autoimmunity 2015 (PubMed)

More Proteins for Thyroid Stimulating Hormone Receptor (TSHR) Interaction Partners

Zebrafish Thyroid Stimulating Hormone Receptor (TSHR) interaction partners

  1. Functional thyroid differentiation in zebrafish was examined and the role of TSHR signaling during thyroid organogenesis, was characterized.

Human Thyroid Stimulating Hormone Receptor (TSHR) interaction partners

  1. TSHR gene polymorphisms are associated with typical symptoms in primary congenital hypothyroidism.

  2. The eminent ratio of TSHr methylation in well-differentiated thyroid carcinoma against benign thyroidal nodules adduced that TSHr methylation status can be utilized as a tumor marker for well-differentiated thyroid cancer.

  3. Thyroid-stimulating hormone receptor intronic polymorphisms are associated with the susceptibility to Graves' disease and Graves' ophthalmopathy in the Brazilian population, but do not appear to influence the disease course.

  4. data support a structural model of the TSHR transmembrane domain with a bulged transmembrane helix TM2 (show TPM2 Proteins) and a straight TM5 that is specific of glycoprotein hormone receptors

  5. TSHR gene variants are associated with congenital hypothyroidism.

  6. the hinge region and its adjacent domains have roles in binding and signaling patterns of the thyrotropin and follitropin receptor (show FSHR Proteins)

  7. subclinical hypothyroidism in heterozygotes with TSHR mutations is a stable compensated condition with an appropriately adjusted set point for pituitary-thyroid feedback that does not require replacement therapy

  8. Patients with preoperative TSHR-mRNA >/=1.02 ng/mug may be at a greater risk for recurrence of thyroid cancer.

  9. The present study demonstrates that the SmartAmp2 method is useful to detect the R450H mutation in TSHR.

  10. The aim of this study was to investigate whether chimeric TSH receptor based bioassay can predict Graves' disease remission/relapse after antithyroid drug

Mouse (Murine) Thyroid Stimulating Hormone Receptor (TSHR) interaction partners

  1. Data indicate that splenic T cells from thyroid stimulating hormone receptor (TSHR) A-subunit primed animals undergoing Graves' orbitopathy (GO) showed proliferative responses to purified TSHR antigen and secreted proinflammatory cytokines.

  2. Lung fibroblasts of TSHR KO mice have decreased cell surface Igf1r (show IGF1R Proteins) expression, and have Igf1r (show IGF1R Proteins) protein and protein fragments in both cytoplasm and nucleus. Igf1r (show IGF1R Proteins) mRNA levels were similar between TSHR KO and WT mice.

  3. The mechanism, underlying TSH-induced liver triglyceride accumulation, involved that TSH, through its receptor TSHR, triggered hepatic SREBP-1c (show SREBF1 Proteins) activity.

  4. These findings suggest that activation of TSHR directly inhibits FASN (show FASN Proteins) expression in mature adipocytes, possibly mediated by PKA and ERK (show EPHB2 Proteins)

  5. A novel role for TSHR in behavioral and neurological phenotypes of Attention deficit/hyperactivity disorder.

  6. The data indicate functional TSHR is expressed in ventricular myocytes and mediates TSH-induced BNP secretion and HMGCR (show HMGCR Proteins) up-regulation through the cAMP/PKA/pCREB signaling pathway.

  7. findings demonstrate TSH-R expression is thymus-specific within the immune system; data support the notion of a novel neuroendocrine-immune interaction in which TSH-R signaling in the thymus, most likely mediated by TSH, enhances thymic T-cell development

  8. The inhibition of hepatic PEPCK (show PEPCK Proteins) and G6P and enhanced expression of GK contributed to the development of fasting hypoglycemia in Tshr-ko mice.

  9. UCP-1 (show UCP1 Proteins) and TSHR co-localized in retrobulbar adipose tissues in murine models of Graves' disease.

  10. Cloned a thyroid-stimulating hormone receptor (TSHR) cDNA from thyroid glands. The sequence of this cDNA indicated that it encoded a 739 amino acid TSHR splice variant that lacked exon 5 (TSHR739).

Cow (Bovine) Thyroid Stimulating Hormone Receptor (TSHR) interaction partners

  1. Localization of thyrotropin receptor and thyroglobulin (show TG Proteins) in the bovine corpus luteum.

  2. analysis of activation switch in the thyrotropin receptor

  3. Rhes (show RASD2 Proteins) can interfere with the functional activity of wt and mutated TSHr.

  4. Increased receptor binding by bovine (b) TSH bound to monoclonal antibody to bTSHbeta-subunit.

  5. the hinge region represents an extracellular intermediate connector for both hormone binding and signal transduction of the thyroid stimulating hormone receptor

Horse (Equine) Thyroid Stimulating Hormone Receptor (TSHR) interaction partners

  1. The equine TSHR is not responsive to equine chorionic gonadotropin but is more sensitive to human CG than the human TSHR

TSH receptor (TSHR) Protein Profile

Protein Summary

The protein encoded by this gene is a membrane protein and a major controller of thyroid cell metabolism. The encoded protein is a receptor for thyrothropin and thyrostimulin, and its activity is mediated by adenylate cyclase. Defects in this gene are a cause of several types of hyperthyroidism. Three transcript variants encoding different isoforms have been found for this gene.

Gene names and symbols associated with TSHR

  • thyroid stimulating hormone receptor (tshr)
  • thyroid stimulating hormone receptor (TSHR)
  • thyrotropin receptor (TSH-R)
  • thyroid stimulating hormone receptor (Tshr)
  • AI481368 protein
  • CHNG1 protein
  • hTSHR-I protein
  • hypothroid protein
  • hyt protein
  • LGR3 protein
  • pet protein
  • TSH-R protein
  • TSHRA protein

Protein level used designations for TSHR

TSH receptor , thyroid-stimulating hormone receptor , thyrotropin receptor , seven transmembrane helix receptor , thyrotropin receptor-I, hTSHR-I , TSH-R

GENE ID SPECIES
560609 Danio rerio
574251 Macaca mulatta
100534416 Oreochromis niloticus
7253 Homo sapiens
397560 Sus scrofa
22095 Mus musculus
25360 Rattus norvegicus
428900 Gallus gallus
403968 Canis lupus familiaris
281553 Bos taurus
100721620 Cavia porcellus
493842 Felis catus
443428 Ovis aries
100052603 Equus caballus
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