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TJP1 encodes a protein located on a cytoplasmic membrane surface of intercellular tight junctions. Additionally we are shipping TJP1 Kits (43) and TJP1 Proteins (4) and many more products for this protein.
Showing 10 out of 85 products:
Dog (Canine) Polyclonal TJP1 Primary Antibody for IHC (fro), FACS - ABIN1109613
Pelletier, Okawara, Vitale, Anderson: Differential distribution of the tight-junction-associated protein ZO-1 isoforms alpha+ and alpha- in guinea pig Sertoli cells: a possible association with F-actin and G-actin. in Biology of reproduction 1997
Show all 5 references for ABIN1109613
Human Monoclonal TJP1 Primary Antibody for IF, WB - ABIN968282
Ebnet, Schulz, Meyer Zu Brickwedde, Pendl, Vestweber: Junctional adhesion molecule interacts with the PDZ domain-containing proteins AF-6 and ZO-1. in The Journal of biological chemistry 2000
Show all 4 references for ABIN968282
Human Polyclonal TJP1 Primary Antibody for IF (cc), IF (p) - ABIN675024
Gu, Xue, Wei, Zhang, Li: Calcium-activated potassium channel activator down-regulated the expression of tight junction protein in brain tumor model in rats. in Neuroscience letters 2011
Show all 3 references for ABIN675024
Dog (Canine) Polyclonal TJP1 Primary Antibody for IHC (fro), IF - ABIN1109612
Balda, Anderson: Two classes of tight junctions are revealed by ZO-1 isoforms. in The American journal of physiology 1993
Show all 3 references for ABIN1109612
Human Polyclonal TJP1 Primary Antibody for FACS, IHC (p) - ABIN650980
Ohira, Oshitani, Hosomi, Watanabe, Yamagami, Tominaga, Watanabe, Fujiwara, Maeda, Hirakawa, Arakawa: Dislocation of Rab13 and vasodilator-stimulated phosphoprotein in inactive colon epithelium in patients with Crohn's disease. in International journal of molecular medicine 2009
Show all 2 references for ABIN650980
Dog (Canine) Polyclonal TJP1 Primary Antibody for IHC, WB - ABIN2774876
Shen, Weber, Turner: The tight junction protein complex undergoes rapid and continuous molecular remodeling at steady state. in The Journal of cell biology 2008
Human Polyclonal TJP1 Primary Antibody for EIA, WB - ABIN487963
Zhong, Deane, Ali, Parisi, Shapovalov, OBanion, Stojanovic, Sagare, Boillee, Cleveland, Zlokovic: ALS-causing SOD1 mutants generate vascular changes prior to motor neuron degeneration. in Nature neuroscience 2008
The data suggest that ZO-1, along with CD38 and Zap-70 (show ZAP70 Antibodies), plays a role in cell cycle regulation in chronic B cell leukemia, and may be used as a prognostic marker in the disease monitoring.
These data provide the first evidence that beta-catenin (show CTNNB1 Antibodies) and ZO-1 are direct targets of E7 of the oncogenic beta-human papillomavirus types 5 and 8.
Report TNF-alpha (show TNF Antibodies)/Il6 (show IL6 Antibodies) mediated dysregulation of zonula occludens-1 properties in human brain microvascular endothelium.
upon specific knockdown of the accessory TJP, ZO-1, undifferentiated NSCs showed decreased levels of key stem cell markers
HTT (show HTT Antibodies) may inhibit breast tumor dissemination through maintenance of ZO1 at tight junctions.
These results suggest that the localization of ZO-1 in cell-cell contacts is differently regulated by activation and inhibition of JNK (show MAPK8 Antibodies) and/or p38 MAPK (show MAPK14 Antibodies) depending on the incubation period.
CFTR (show CFTR Antibodies) colocalizes with ZO-1 at the tight junctions of trachea and epididymis, and is expressed before ZO-1 in Wolffian ducts.
Phosphorylation state of the tyrosine of claudin-1 (show CLDN7 Antibodies) and claudin-2 (show CLDN2 Antibodies) regulates interaction with ZO1.
miR (show MLXIP Antibodies)-18a and RUNX1 (show RUNX1 Antibodies) could reversely regulate the permeability of blood-tumor barrier as well as the expressions and distributions of ZO-1, occludin (show OCLN Antibodies) and claudin-5 (show CLDN5 Antibodies).
Zonula occludens-1, occludin (show OCLN Antibodies) and E-cadherin (show CDH1 Antibodies) expression and organization in salivary glands
Cx43 (show GJA1 Antibodies) tethers the F-actin cytoskeleton through a ZO-1 linker and supports cell spreading and exploration during locomotion in cerebral endothelial cells.
Expression of Podocalyxin (show PODXL Antibodies), which positively regulates the formation of microvilli and the apical membrane, is repressed in embryoid bodies lacking both ZO-1 and ZO-2 (show TJP2 Antibodies) and this correlates with an aberrant submembranous localization of Ezrin (show EZR Antibodies).
Tjp1 expression was decreased in glomerular diseases in human and animal models, our results indicate that the suppression of Tjp1 could directly aggravate glomerular disorders, highlights Tjp1 as a potential therapeutic target.
Arecoline increases the production of TNF-alpha (show TNF Antibodies) and induces protein redistribution of ZO-1.
Vcl (show VCL Antibodies) plays a crucial role in stabilizing gap junctions and myocyte integrity through direct interactions with ZO-1 and stabilization of CX43 (show GJA1 Antibodies).
Activation of RhoA (show RHOA Antibodies)/ROCK1 (show ROCK1 Antibodies) by high glucose in diabetic nephropathy disrupts the expression and translocation of occludin (show OCLN Antibodies)/ZO-1, which can be corrected by simvastatin.
Vascular endothelial tight junctions and barrier function are disrupted by 15(S)-hydroxyeicosatetraenoic acid partly via protein kinase C epsilon (show PRKCE Antibodies)-mediated zona occludens-1 phosphorylation at threonine 770/772.
The JAM-A (show F11R Antibodies) and ZO-1 genes were highly expressed in all the tested tissues.
The results establish that ZO-1 acts as a true scaffolding protein and that the coordinated activity of multiple domains is required for normal TJ structure and function.
cyclic strain modulates both the expression and phosphorylation state of occludin (show OCLN Antibodies) and ZO-1 in vascular endothelial cells, with putative consequences for endothelial tight junction assembly and barrier integrity
ZO-1 and occludin (show OCLN Antibodies) are expressed in oocytes and preimplantation embryos, and that ZO-1alpha+ is transcribed by zygotic gene activation and translated from early blastocysts with prominent increase of occludin (show OCLN Antibodies) at the blastocyst stage.
This gene encodes a protein located on a cytoplasmic membrane surface of intercellular tight junctions. The encoded protein may be involved in signal transduction at cell-cell junctions. Two transcript variants encoding distinct isoforms have been identified for this gene.
tight junction protein ZO-1
, zona occludens 1
, zona occludens protein 1
, zonula occludens 1 protein
, zonula occludens protein 1
, tight junction protein 1 (zona occludens 1)
, zonula occludens 1