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anti-Tight Junction Protein 2 (Zona Occludens 2) (TJP2) Antibodies

TJP2 encodes a zonula occluden that is a member of the membrane-associated guanylate kinase homolog family. Additionally we are shipping TJP2 Kits (5) and TJP2 Proteins (3) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
TJP2 9414 Q9UDY2
TJP2 21873 Q9Z0U1
TJP2 115769  
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Top anti-TJP2 Antibodies at antibodies-online.com

Showing 10 out of 103 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Chicken Rabbit Un-conjugated WB WB Suggested Anti-TJP2 Antibody Titration: 0.2-1 ug/mlELISA Titer: 1:62500Positive Control: Jurkat cell lysate 100 μL Log in to see 2 to 3 Days
$289.00
Details
Dog Rabbit Un-conjugated WB WB Suggested Anti-TJP2 Antibody Titration: 0.2-1 ug/mlELISA Titer: 1:1562500Positive Control: MCF7 cell lysate WB Suggested Anti-TJP2  Antibody Titration: 0.2-1 µg/mL ELISA Titer: 1:1562500  Positive Control: MCF7 cell lysate  TJP2 is supported by BioGPS gene expression data to be expressed in MCF7 100 μL Log in to see 2 to 3 Days
$289.00
Details
Mouse Rabbit Un-conjugated IHC (p), WB Anti-TJP2 antibody, IHC(P) IHC(P): Mouse Liver Tissue Anti-TJP2 antibody, Western blotting Lane 1: Rat Brain Tissue Lysate Lane 2: PC-12 Cell Lysate Lane 3: Mouse Brain Tissue Lysate Lane 4: HEPA Cell Lysate 100 μg Log in to see 4 to 6 Days
$200.00
Details
Human Rabbit Un-conjugated DB Dot blot analysis of Phospho-PTEN-Y240 Antibody Phospho-specific Pab  on nitrocellulose membrane. 50ng of Phospho-peptide or Non Phospho-peptide per dot were adsorbed. Antibody working concentrations are 0.6ug per ml. 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Rabbit Un-conjugated WB WB Image Sample (30 ug of whole cell lysate) A: U87-MG 5% SDS PAGE antibody diluted at 1:500 100 μL Log in to see 2 to 3 Days
$358.60
Details
Human Rabbit Un-conjugated IHC (fro), IHC (p), WB Anti-TJP2 antibody, IHC(P) IHC(P): Human Intestinal Cancer Tissue Anti-TJP2 antibody, Western blotting Lane 1: 293T Cell Lysate Lane 2: MCF-7 Cell Lysate 100 μg Log in to see 4 to 6 Days
$200.00
Details
Human Rabbit Un-conjugated WB TJP2 Antibody (C-term)  western blot analysis in U937 cell line lysates (35ug/lane).This demonstrates the TJP2 antibody detected the TJP2 protein (arrow). 400 μL Log in to see 10 to 11 Days
$324.50
Details
Dog Rabbit Un-conjugated ELISA, WB 50 μg Log in to see 2 to 3 Days
$433.13
Details
Human Rabbit Un-conjugated WB 50 μg Log in to see 8 to 10 Days
$551.83
Details
Human Rabbit Un-conjugated WB 50 μg Log in to see 8 to 10 Days
$551.83
Details

TJP2 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
Human , , , ,
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Mouse (Murine)
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Rat (Rattus)


Top referenced anti-TJP2 Antibodies

  1. Chicken Polyclonal TJP2 Primary Antibody for WB - ABIN2775643 : Bel Hadj Ali, Thys, Beltaief, Schrauwen, Hilgert, Vanderstraeten, Dieltjens, Mnif, Hachicha, Besbes, Ben Arab, Van Camp: A new locus for otosclerosis, OTSC8, maps to the pericentromeric region of chromosome 9. in Human genetics 2008 (PubMed)

More Antibodies against TJP2 Interaction Partners

Human Tight Junction Protein 2 (Zona Occludens 2) (TJP2) interaction partners

  1. Claudin-19 (show CLDN19 Antibodies), the most abundant claudin in myelin, exhibited no binding to ZO2.

  2. JAM-A (show F11R Antibodies) regulates epithelial permeability via association with ZO-2, afadin (show MLLT4 Antibodies), and PDZ-GEF1 (show RAPGEF2 Antibodies) to activate Rap2c (show RAP2C Antibodies) and control contraction of the apical cytoskeleton.

  3. Protein-truncating mutations in the tight junction protein 2 gene cause failure of protein localization and disruption of tight-junction structure, leading to severe cholestatic liver disease.

  4. demonstrated that ZO-2 inhibition increases invasive and migrative capacities of invasive tumor cells. This was associated with an increase of MT1-MMP (show MMP14 Antibodies)

  5. the Alu-related transcript of TJP2 gene (TJP2-Alu transcript) was differentially expressed between colorectal tumor and normal tissues; potential diagnostic markers for colorectal cancer.

  6. ZO-2 inhibits the Wnt (show WNT2 Antibodies) signaling pathway, reduces cell proliferation, and promotes apoptosis; its absence, mutation, or overexpression is present in various human diseases, including deafness and cancer.

  7. AmotL1 (show AMOTL1 Antibodies) and ZO-2 are two candidates that could be harnessed to control the oncogenic function of YAP (show YAP1 Antibodies).

  8. these findings imply involvement of the ZO-2 tight junction independent signaling complex containing Jak1 (show JAK1 Antibodies) and uPAR (show PLAUR Antibodies) in VSMC intercellular communications.

  9. ZO-2 interacts with (show INADL Antibodies)YAP2 to form complex; ZO-2 f (show YAP1 Antibodies)acilitates both nuclear translocation of YAP2 & pro-apoptotic functio (show YAP1 Antibodies)n of YAP2; YAP2/ZO-2 complex appe (show YAP1 Antibodies)ars to be involved in cell detachment

  10. The identification of ZASP (show LDB3 Antibodies) helps to unfold the complex nuclear molecular arrays that form on ZO-2 scaffolds.

Mouse (Murine) Tight Junction Protein 2 (Zona Occludens 2) (TJP2) interaction partners

  1. Expression of Podocalyxin (show PODXL Antibodies), which positively regulates the formation of microvilli and the apical membrane, is repressed in embryoid bodies lacking both ZO-1 (show TJP1 Antibodies) and ZO-2 and this correlates with an aberrant submembranous localization of Ezrin (show EZR Antibodies).

  2. SNX27 (show SNX27 Antibodies) associates with ZO-2 and modulates the epithelial tight junction.

  3. ZO-2 protects against podocyte dysfunction induced by adreiamycin. This action is regulated by ZO-2-mediated inhibition of the Wnt (show WNT2 Antibodies)/beta-catenin (show CTNNB1 Antibodies) signaling pathway

  4. the first PDZ domain (show INADL Antibodies) of ZO-2 interacts with YAP2 (show YAP1 Antibodies) to form complex; ZO-2 facilitates both nuclear translocation of YAP2 (show YAP1 Antibodies) & pro-apoptotic function of YAP2 (show YAP1 Antibodies); these activities of ZO-2 are PDZ-domain (show INADL Antibodies)-dependent

  5. Male ZO-2 chimeras show reduced fertility and pathological changes in the testis. Lanthanum tracer experiments show a compromised blood-testis barrier.

  6. nuclear ZO-2 is present in epithelial and endothelial cells, particularly in response to environmental stress conditions

  7. ZO-1 (show TJP1 Antibodies) and ZO-2 function redundantly to some extent in junction formation/epithelial polarization but they are not functionally identical

  8. These findings indicate that ZO-1 (show TJP1 Antibodies) and ZO-2 can independently determine whether and where claudins are polymerized.

  9. These results suggest novel roles for ZO proteins as Src (show SRC Antibodies)/Csk (show CSK Antibodies) scaffolds potentially involved in the regulation of Src (show SRC Antibodies) transformation.

  10. Early embryonic lethality of mice lacking Tjp2, but not Tjp3 (show TJP3 Antibodies), reveal critical and nonredundant roles for individual zonula occludens proteins in mammalian development.

TJP2 Antigen Profile

Protein Summary

This gene encodes a zonula occluden that is a member of the membrane-associated guanylate kinase homolog family. The encoded protein functions as a component of the tight junction barrier in epithelial and endothelial cells and is necessary for proper assembly of tight junctions. Mutations in this gene have been identified in patients with hypercholanemia, and genomic duplication of a 270 kb region including this gene causes autosomal dominant deafness-51. Alternatively spliced transcripts encoding multiple isoforms have been observed for this gene.

Gene names and symbols associated with TJP2

  • tight junction protein 2 (TJP2) antibody
  • tight junction protein 2 (Tjp2) antibody
  • tight junction protein 2 (zona occludens 2) (TJP2) antibody
  • C9DUPq21.11 antibody
  • DFNA51 antibody
  • DUP9q21.11 antibody
  • X104 antibody
  • ZO-2 antibody
  • zo2 antibody

Protein level used designations for TJP2

tight junction protein 2 (zona occludens 2) , Friedreich ataxia region gene X104 (tight junction protein ZO-2) , tight junction protein ZO-2 , zona occludens 2 , zonula occludens protein 2 , Tight junction protein ZO-2 (Zonula occludens 2 protein) (Zona occludens 2 protein) (Tight junction protein 2) , zona occludens protein 2

GENE ID SPECIES
100229218 Taeniopygia guttata
9414 Homo sapiens
21873 Mus musculus
115769 Rattus norvegicus
100729549 Cavia porcellus
395751 Gallus gallus
403854 Canis lupus familiaris
407101 Bos taurus
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