Tight Junction Protein 2 (Zona Occludens 2) (TJP2) ELISA Kits

TJP2 encodes a zonula occluden that is a member of the membrane-associated guanylate kinase homolog family. Additionally we are shipping TJP2 Antibodies (105) and TJP2 Proteins (4) and many more products for this protein.

list all ELISA KIts Gene Name GeneID UniProt
TJP2 9414 Q9UDY2
Anti-Mouse TJP2 TJP2 21873 Q9Z0U1
Anti-Rat TJP2 TJP2 115769  
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Top TJP2 ELISA Kits at antibodies-online.com

Showing 1 out of 6 products:

Catalog No. Reactivity Sensitivity Range Images Quantity Supplier Delivery Price Details
Human 4.68 pg/mL 18.75-1200 pg/mL Typical standard curve 96 Tests Log in to see 15 to 18 Days

More ELISA Kits for TJP2 Interaction Partners

Human Tight Junction Protein 2 (Zona Occludens 2) (TJP2) interaction partners

  1. Patients with a confirmed ABCB11 (show ABCB11 ELISA Kits) or tight junction protein 2 gene mutation (n = 7) had a minimally detectable THBA proportion (0.23-2.99% of total BAs). Three patients with an ATP8B1 (show ATP8B1 ELISA Kits) mutation had an elevated THBA proportion (7.51-37.26%).

  2. Studies indicate the modular and supramodular organization of zonula occludens protein 2 (ZO-2) that allows it to interact with a wide variety of molecules, including cell-cell adhesion proteins, cytoskeletal components, and nuclear factors.

  3. Data identified two Disease-causing Genes TJP2 and GJB2 (show GJB2 ELISA Kits) in a Chinese Family with Unconditional Autosomal Dominant Nonsyndromic Hereditary Hearing Impairment.

  4. TJP2 deficiency may predispose to hepatocellular carcinoma in early childhood

  5. Claudin-19 (show CLDN19 ELISA Kits), the most abundant claudin in myelin, exhibited no binding to ZO2.

  6. JAM-A (show F11R ELISA Kits) regulates epithelial permeability via association with ZO-2, afadin (show MLLT4 ELISA Kits), and PDZ-GEF1 (show RAPGEF2 ELISA Kits) to activate Rap2c (show RAP2C ELISA Kits) and control contraction of the apical cytoskeleton.

  7. Protein-truncating mutations in the tight junction protein 2 gene cause failure of protein localization and disruption of tight-junction structure, leading to severe cholestatic liver disease.

  8. demonstrated that ZO-2 inhibition increases invasive and migrative capacities of invasive tumor cells. This was associated with an increase of MT1-MMP (show MMP14 ELISA Kits)

  9. the Alu-related transcript of TJP2 gene (TJP2-Alu transcript) was differentially expressed between colorectal tumor and normal tissues; potential diagnostic markers for colorectal cancer.

  10. ZO-2 inhibits the Wnt (show WNT2 ELISA Kits) signaling pathway, reduces cell proliferation, and promotes apoptosis; its absence, mutation, or overexpression is present in various human diseases, including deafness and cancer.

Mouse (Murine) Tight Junction Protein 2 (Zona Occludens 2) (TJP2) interaction partners

  1. Expression of Podocalyxin (show PODXL ELISA Kits), which positively regulates the formation of microvilli and the apical membrane, is repressed in embryoid bodies lacking both ZO-1 (show TJP1 ELISA Kits) and ZO-2 and this correlates with an aberrant submembranous localization of Ezrin (show EZR ELISA Kits).

  2. SNX27 (show SNX27 ELISA Kits) associates with ZO-2 and modulates the epithelial tight junction.

  3. ZO-2 protects against podocyte dysfunction induced by adreiamycin. This action is regulated by ZO-2-mediated inhibition of the Wnt (show WNT2 ELISA Kits)/beta-catenin (show CTNNB1 ELISA Kits) signaling pathway

  4. the first PDZ domain (show INADL ELISA Kits) of ZO-2 interacts with YAP2 (show YAP1 ELISA Kits) to form complex; ZO-2 facilitates both nuclear translocation of YAP2 (show YAP1 ELISA Kits) & pro-apoptotic function of YAP2 (show YAP1 ELISA Kits); these activities of ZO-2 are PDZ-domain (show INADL ELISA Kits)-dependent

  5. Male ZO-2 chimeras show reduced fertility and pathological changes in the testis. Lanthanum tracer experiments show a compromised blood-testis barrier.

  6. nuclear ZO-2 is present in epithelial and endothelial cells, particularly in response to environmental stress conditions

  7. ZO-1 (show TJP1 ELISA Kits) and ZO-2 function redundantly to some extent in junction formation/epithelial polarization but they are not functionally identical

  8. These findings indicate that ZO-1 (show TJP1 ELISA Kits) and ZO-2 can independently determine whether and where claudins are polymerized.

  9. These results suggest novel roles for ZO proteins as Src (show SRC ELISA Kits)/Csk (show CSK ELISA Kits) scaffolds potentially involved in the regulation of Src (show SRC ELISA Kits) transformation.

  10. Early embryonic lethality of mice lacking Tjp2, but not Tjp3 (show TJP3 ELISA Kits), reveal critical and nonredundant roles for individual zonula occludens proteins in mammalian development.

TJP2 Antigen Profile

Antigen Summary

This gene encodes a zonula occluden that is a member of the membrane-associated guanylate kinase homolog family. The encoded protein functions as a component of the tight junction barrier in epithelial and endothelial cells and is necessary for proper assembly of tight junctions. Mutations in this gene have been identified in patients with hypercholanemia, and genomic duplication of a 270 kb region including this gene causes autosomal dominant deafness-51. Alternatively spliced transcripts encoding multiple isoforms have been observed for this gene.

Gene names and symbols associated with TJP2

  • tight junction protein 2 (TJP2) antibody
  • tight junction protein 2 (Tjp2) antibody
  • tight junction protein 2 (zona occludens 2) (TJP2) antibody
  • C9DUPq21.11 antibody
  • DFNA51 antibody
  • DUP9q21.11 antibody
  • X104 antibody
  • ZO-2 antibody
  • zo2 antibody

Protein level used designations for TJP2

tight junction protein 2 (zona occludens 2) , Friedreich ataxia region gene X104 (tight junction protein ZO-2) , tight junction protein ZO-2 , zona occludens 2 , zonula occludens protein 2 , Tight junction protein ZO-2 (Zonula occludens 2 protein) (Zona occludens 2 protein) (Tight junction protein 2) , zona occludens protein 2

100229218 Taeniopygia guttata
9414 Homo sapiens
21873 Mus musculus
115769 Rattus norvegicus
100729549 Cavia porcellus
395751 Gallus gallus
403854 Canis lupus familiaris
407101 Bos taurus
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