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Tocopherol (Alpha) Transfer Protein (TTPA) ELISA Kits

TTPA encodes a soluble protein that binds alpha-trocopherol, a form of vitamin E, with high selectivity and affinity. Additionally we are shipping TTPA Antibodies (25) and TTPA Proteins (5) and many more products for this protein.

list all ELISA KIts Gene Name GeneID UniProt
TTPA 7274 P49638
TTPA 25571 P41034
TTPA 50500 Q8BWP5
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Top TTPA ELISA Kits at antibodies-online.com

Showing 4 out of 10 products:

Catalog No. Reactivity Sensitivity Range Images Quantity Supplier Delivery Price Details
Mouse 0.055 ng/mL 0.15-10 ng/mL 96 Tests Log in to see 9 to 11 Days
$757.89
Details
Human 0.156-10 ng/mL   96 Tests Log in to see 11 to 13 Days
$875.60
Details
Chicken
  96 Tests Log in to see 16 to 21 Days
$999.43
Details
Rat
  96 Tests Log in to see 16 to 21 Days
$999.43
Details

More ELISA Kits for TTPA Interaction Partners

Human Tocopherol (Alpha) Transfer Protein (TTPA) interaction partners

  1. Single-nucleotide polymorphisms that are commonly found in healthy humans dramatically affect promoter activity of the TTPA gene.

  2. The crystal structure of the alpha-TTP-phosphatidylinositol phosphates (PIPs (show GPRASP1 ELISA Kits)) complex revealed that the familial vitamin E deficiency-related arginine residues interacted with phosphate groups of the PIPs (show GPRASP1 ELISA Kits) and that the PIPs (show GPRASP1 ELISA Kits) binding caused the lid of the alpha-tocopherol-binding pocket to open.

  3. Data show that reduction ("knockdown") of tocopherol transfer protein (TTP (show ADAMTS13 ELISA Kits)) expression resulted in resistance to the vitamin E.

  4. Substitution of residues in helices A8 (F165A and F169A) and A10 (I202A, V206A and M209A) decreased the rate of intermembrane ligand transfer as well as protein adsorption to phospholipid bilayers.

  5. First case of a mutated form of the TTPA gene in a patient also carrying a spinocerebellar ataxia (show USP14 ELISA Kits) type 8 expansion.

  6. the positively charged surface of TTPA may serve to orient an interacting protein, which might function to regulate the release of alpha-T through an induced change in conformation of ATTP

  7. Findings suggest the possibility that ataxia (show USP14 ELISA Kits) with vitamin E deficiency syndrome (AVED) may not arise from an inability of TTP (show ADAMTS13 ELISA Kits) to bind or to transfer alpha tocopherol, but rather from defects in other activities of the protein.

  8. Nuclear localization of TTPA in in trophoblast, fetal capillaries' endothelium and amnion epithelium of human term placentamay represent a novel function of TTPA

  9. In Ataxia (show USP14 ELISA Kits) with vitamin E deficiency two TTPA mutations were identified: a truncating mutation in a homozygous patient, and a Gly246Arg missense mutation in a compound heterozygous patient associated with a mild and slowly progressive form of the disease.

  10. The physiological role of TTP (show ADAMTS13 ELISA Kits) is anchored in its ability to direct vitamin E trafficking from the endocytic compartment to transport vesicles that deliver the vitamin to the site of secretion at the plasma membrane.

Mouse (Murine) Tocopherol (Alpha) Transfer Protein (TTPA) interaction partners

  1. Results suggest that lipid peroxidation due to depletion of alpha-tocopherol impairs Abeta (show APP ELISA Kits) clearances from the brain and from the blood, possibly causing increased Abeta (show APP ELISA Kits) accumulation in Ttpa(-/-)APPsw brain and plasma.

  2. Endogenous TTPA, through the enhancement of MMP 9 (show MMP9 ELISA Kits) expression and proteolytic activation, plays an essential role in the pathogenesis of heparin-produced cerebral hemorrhage.

  3. TTP (show ZFP36 ELISA Kits) transports alpha-TCP and oral administration of TTP (show ZFP36 ELISA Kits) compensates for TTP (show ZFP36 ELISA Kits) in TTP (show ZFP36 ELISA Kits)-deficient mice

  4. These data suggest that in vivo network of alpha-tocopherol (AT), AT-metabolites and ATTP affects the transcription of genes driven by AhR (show AHR ELISA Kits), Nrf2 (show NFE2L2 ELISA Kits) and NF-kappaB (show NFKB1 ELISA Kits), transcription factor networks.

  5. p75(NTR (show NGFR ELISA Kits))is up-regulated after tissue injury, blocks fibrinolysis by down-regulating the serine protease (show F2 ELISA Kits), tissue plasminogen activator (show PLAT ELISA Kits), and up-regulating PAI-1 (show SERPINE1 ELISA Kits).

  6. changes in hepatic TTP (show ZFP36 ELISA Kits) concentrations were minimal in response to dietary vitamin E levels or environmental tobacco smoke-related oxidative stress

  7. Increase expression of tPA implicate fibrinolysis in ALD progression.

TTPA Antigen Profile

Antigen Summary

This gene encodes a soluble protein that binds alpha-trocopherol, a form of vitamin E, with high selectivity and affinity. This protein plays an important role in regulating vitamin E levels in the body by transporting vitamin E between membrane vesicles and facilitating the secretion of vitamin E from hepatocytes to circulating lipoproteins. Mutations in this gene cause hereditary vitamin E deficiency (ataxia with vitamin E deficiency, AVED) and retinitis pigmentosa.

Gene names and symbols associated with TTPA

  • tocopherol (alpha) transfer protein (TTPA) antibody
  • tocopherol (alpha) transfer protein (ataxia (Friedreich-like) with vitamin E deficiency) (ttpa) antibody
  • tocopherol (alpha) transfer protein (Ttpa) antibody
  • alpha-TTP antibody
  • alphaTTP antibody
  • ATTP antibody
  • AVED antibody
  • TTP antibody
  • TTP1 antibody

Protein level used designations for TTPA

alpha-tocopherol transfer protein , tocopherol (alpha) transfer protein , alpha-TTP , tocopherol (alpha) transfer protein (ataxia (Friedreich-like) with vitamin E deficiency) , Alpha-tocopherol transfer protein , Tocopherol transfer protein alpha , alpha TTP

GENE ID SPECIES
286813 Bos taurus
403627 Canis lupus familiaris
472778 Pan troglodytes
771074 Gallus gallus
100196332 Salmo salar
100526668 Ovis aries
7274 Homo sapiens
25571 Rattus norvegicus
50500 Mus musculus
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