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TOLLIP encodes a ubiquitin-binding protein that interacts with several Toll-like receptor (TLR) signaling cascade components. Additionally we are shipping TOLLIP Proteins (17) and TOLLIP Kits (9) and many more products for this protein.
Showing 10 out of 161 products:
Human Polyclonal TOLLIP Primary Antibody for IHC (p), WB - ABIN1882142
Volpe, Clatworthy, Kaptein, Maschera, Griffin, Ray: The IL1 receptor accessory protein is responsible for the recruitment of the interleukin-1 receptor associated kinase to the IL1/IL1 receptor I complex. in FEBS letters 1998
Show all 5 references for ABIN1882142
Chicken Polyclonal TOLLIP Primary Antibody for WB - ABIN2777431
Schimming, Parwez, Petrasch-Parwez, Nothnagel, Epplen, Hoffjan: Association of toll-interacting protein gene polymorphisms with atopic dermatitis. in BMC dermatology 2007
Human Polyclonal TOLLIP Primary Antibody for IHC (fro), WB - ABIN265153
Takeda, Kaisho, Akira: Toll-like receptors. in Annual review of immunology 2003
Toll-interacting protein rs5743867 polymorphism tends to decrease the risk of sepsis in infants undergoing complex open heart surgery.
Variants in the TOLLIP gene are associated with higher circulating PAI-1 (show SERPINE1 Antibodies) plasma levels and association with clinical Primary Graft Dysfunction Risk.
Tom1 (show TOM1 Antibodies) modulates binding of Tollip to phosphatidylinositol 3-phosphate via a coupled folding and binding mechanism.
These data suggest that M. leprae upregulates IL-1Ra (show IL1RN Antibodies) by a TOLLIP-dependent mechanism; inhibition of TOLLIP may decrease an individual's susceptibility to leprosy and offer a novel therapeutic target for IL-1 (show IL1A Antibodies)-dependent diseases.
Observed expression patterns of several TLR inhibitory proteins with a noticeable suppression in expression of two of these; PPARgamma (show PPARG Antibodies) and TOLLIP in both ulcerative colitis and Crohn's disease and in both active and inactive disease states.
Tollip acts as a novel modulator of I/R injury by promoting neuronal apoptosis and ischaemic inflammation, which are largely mediated by suppression of Akt (show AKT1 Antibodies) signalling.
The two polymorphisms, rs5743899 and rs3750920, in the TOLLIP gene are independently associated with an increased risk of developing cutaneous leishmaniasis (CL).
TOLLIP encodes toll-interacting protein (TOLLIP), which is an inhibitory adaptor protein acting downstream from the toll (show TLR4 Antibodies)-like receptors (TLRs). Read More: http://www.atsjournals.org/doi/full/10.1164/rccm.201505-1010OC#.VwqiYdLrvyA
we identify a novel function of Tollip in regulating the canonical Wnt (show WNT2 Antibodies) pathway which is evolutionarily conserved between fish and humans. Tollip-mediated inhibition of Wnt (show WNT2 Antibodies) signaling may contribute to embryonic development and to carcinogenesis.
TOLLIP contributes to mortality following myocardial infarction through promoting inflammation and apoptosis
Data show that histone lysine methyltransferase Ezh1 (show EZH1 Antibodies) promotes toll (show TLR4 Antibodies)-like receptor (TLR)-triggered inflammatory cytokine production by suppressing the Toll-interacting protein (Tollip), contributing to full activation of the innate immunity.
Overall, our data show an essential role for Tollip on colitis susceptibility in mice.
negative regulator of pathological cardiac hypertrophy by blocking the AKT (show AKT1 Antibodies) signalling pathway
Tollip cooperates with Smad7 (show SMAD7 Antibodies) to modulate intracellular trafficking and degradation of ubiquitinated TbetaRI (show TGFBR1 Antibodies), whereby negatively regulates TGF-beta (show TGFB1 Antibodies) signaling pathway.
DNA and protein coimmunization induces regulatory dendritic cells through caveolin-1 (show CAV1 Antibodies)- and Tollip-mediated negative signaling.
Low-dose lipopolysaccharide utilizes Tollip and interleukin (IL)-1 (show IL1A Antibodies) receptor-associated kinase (IRAK)-1 (show IRAK1 Antibodies) to induce mitochondrial reactive oxygen species to subsequently induce activating transcription factor (ATF)2 (show ATF2 Antibodies) in chronic low-grade inflammatory disease.
Tollip is a critical mediator responsible for the anti-inflammatory action of epigallocatechin-3-gallate in activated macrophages.
a Tom1-Tollip complex functions as a factor that links polyubiquitinated proteins to clathrin
identified two closely related Tollip-encoding genes in Atlantic salmon (Salmo salar)
This gene encodes a ubiquitin-binding protein that interacts with several Toll-like receptor (TLR) signaling cascade components. The encoded protein regulates inflammatory signaling and is involved in interleukin-1 receptor trafficking and in the turnover of IL1R-associated kinase.
, toll interacting protein
, adapter protein
, toll-interacting protein B
, toll-interacting protein A
, Toll-interleukin 1 receptor interacting protein