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Participates in the innate immune response to microbial agents. Additionally we are shipping Toll-Like Receptor 11 Proteins (4) and many more products for this protein.
Showing 10 out of 50 products:
Mouse (Murine) Polyclonal Tlr11 Primary Antibody for ICC, ELISA - ABIN1003320
Takeda, Kaisho, Akira: Toll-like receptors. in Annual review of immunology 2003
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Mouse (Murine) Polyclonal Tlr11 Primary Antibody for ICC, ELISA - ABIN1003321
Janeway, Medzhitov: Innate immune recognition. in Annual review of immunology 2002
Show all 4 references for ABIN1003321
Mouse (Murine) Polyclonal Tlr11 Primary Antibody for EIA, IF - ABIN500942
Vogel, Fitzgerald, Fenton: TLRs: differential adapter utilization by toll-like receptors mediates TLR-specific patterns of gene expression. in Molecular interventions 2004
mechanisms of interaction with flagellin (show FliC Antibodies) and profilin (show PFN1 Antibodies)
Data show that TLR11 expression is induced in astrocytes, neurons, and microglia in the immune response to T. gondii infection
TLR11 mediates innate immune function of male germ cells in response to T. gondii profilin (show PFN1 Antibodies) and uropathogenic escherichia coli stimulations.
Biochemical experiments revealed that TLR11 and TLR12 (show Tlr12 Antibodies) directly bind to Toxoplasma gondii profilin (show PFN1 Antibodies) and are capable of forming a heterodimer complex.
Selective elimination of neutrophils in TLR11-deficient mice infected with Toxoplasma gondii results in acute susceptibility similar to that observed in IFN-gamma (show IFNG Antibodies)-deficient mice.
While parasite RNA and DNA activate innate immune responses via TLR7 (show TLR7 Antibodies) and TLR9 (show TLR9 Antibodies), TLR11 and TLR12 (show Tlr12 Antibodies) heterodimers are required for sensing and responding to Toxoplasma profilin (show PFN1 Antibodies) infection.
a potentially important role for TLR11 in preventing murine intestinal infection and modulating antigen transportation in the gut (show GUSB Antibodies) and imply an important role for various TLRs in cooperation with tight control of pathogens penetrating into Peyer patches.
association with UNC93B1 (show UNC93B1 Antibodies) and the intracellular localization of TLRs are not unique features of nucleic acid-sensing TLRs but is also essential for TLR11-dependent recognition of T. gondii profilin (show PFN1 Antibodies) and for host protection against this parasite
Data demonstrate that transcription of the Tlr11 gene is regulated through epithelium-specific transcription factors and IRF-8 (show IRF8 Antibodies).
displays a distinct pattern of expression in macrophages and liver, kidney, and bladder epithelial cells; mice lacking TLR11 are highly susceptible to infection of the kidneys by uropathogenic bacteria
Participates in the innate immune response to microbial agents. Acts via MYD88 and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response (By similarity).