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TLL2 encodes an astacin-like zinc-dependent metalloprotease and is a subfamily member of the metzincin family. Additionally we are shipping Tolloid-Like 2 Antibodies (14) and Tolloid-Like 2 Kits (2) and many more products for this protein.
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By means of a cross-species comparative genetic strategy we describe an association for TLL2 with bipolar disorder.
The crystal structures of the protease domains of human BMP-1 (show BMP1 Proteins) and the closely related Tolloid-like (show TLL1 Proteins) protease 1 (TLL-1 (show TLL1 Proteins)), are reported.
loss-of-function mutation in Tll2, has a small, but significant, effect on muscle mass
Xld cleaves Chordin (show CHRD Proteins), an inhibitory binding protein for BMP2/4 (show BMP4 Proteins), releasing fragments with reduced affinity for these important ventralizing signals.
This gene encodes an astacin-like zinc-dependent metalloprotease and is a subfamily member of the metzincin family. Unlike other family members, a similar protein in mice does not cleave procollagen C-propeptides or chordin.
tolloid-like protein 2
, tolloid-like 2
, tolloid-like protein 2-like
, metalloprotease xolloid
, xenopus tolloid