You are viewing an incomplete version of our website. Please click to reload the website as full version.

Torsin Family 1, Member A (Torsin A) (TOR1A) ELISA Kits

The protein encoded by TOR1A is a member of the AAA family of adenosine triphosphatases (ATPases), is related to the Clp protease/heat shock family and is expressed prominently in the substantia nigra pars compacta. Additionally we are shipping Torsin Family 1, Member A (Torsin A) Antibodies (59) and Torsin Family 1, Member A (Torsin A) Proteins (7) and many more products for this protein.

list all ELISA KIts Gene Name GeneID UniProt
Anti-Rat TOR1A TOR1A 266606  
Anti-Human TOR1A TOR1A 1861 O14656
Anti-Mouse TOR1A TOR1A 30931 Q9ER39
How to order from antibodies-online
  • +1 877 302 8632
  • +1 888 205 9894 (toll-free)
  • Order online
  • orders@antibodies-online.com

More ELISA Kits for Torsin Family 1, Member A (Torsin A) Interaction Partners

Human Torsin Family 1, Member A (Torsin A) (TOR1A) interaction partners

  1. Our patient and three other reported carriers of non-c.907_909delGAG-mutations within the first three exons of TOR1A showed similar phenotypes of adult-onset focal or segmental cervical dystonia

  2. the common rs2296793 and rs3842225 SNPs of TOR1A do not play a major role in cervical dystonia in a Chinese population.

  3. Certain TOR1A genotypes may be regarded as factors predisposing to focal and segmental dystonia.

  4. DYT1 mutations are associated with dystonia disorders

  5. TorA(DeltaE) in Drosophila brains may activate the UPR and increase the expression of HSP22 to compensate for the toxic effects

  6. The results of this study indicate that a loss of function of torsinA during cerebellar synaptogenesis induces important developmental alterations.

  7. This review summarizes the current state of knowledge regarding the potential functions of torsin 1A in the context of hypothetical pathomechanisms responsible for torsion dystonia type 1.

  8. study reports 2 new, putative TOR1A mutations (p.A14_P15del and p.E121K)in dystonia patients that were examined functionally compared with wild-type and 2 known mutations (DeltaE and p.R288Q); findings demonstrate functional changes for all 4 mutations on different levels

  9. Data show that mutation of arginine 563 in lamina-associated polypeptide 1 (show CYP ELISA Kits) (LAP1 (show ANPEP ELISA Kits)) reduces its ability to stimulate TorsinA

  10. DYT1 is caused by mutations of the TOR1A gene, located on 9q34, which causes dysfunction of the D1 direct pathway or the indirect pathway[review]

Mouse (Murine) Torsin Family 1, Member A (Torsin A) (TOR1A) interaction partners

  1. Authors find no effect of this anatomic-specific expression of the DYT1 genotype.

  2. The data suggest that LULL1 (show TOR1AIP2 ELISA Kits) oligomerizes to engage and transiently disassemble torsinA oligomers, and is thereby positioned to transduce cytoplasmic signals to the inner nuclear membrane through torsinA.

  3. These findings demonstrate that dorsal dorsal striatal large cholinergic interneurons have a unique requirement for torsinA function during striatal maturation, and link abnormalities of these cells to dystonic-like movements.

  4. maintaining an appropriate torsinA level is important to sustain normal motor performance, synaptic transmission and plasticity

  5. Dyt1 KI mice exhibit decreased striatal dopamine receptor 1 binding activity and D1R (show DRD1 ELISA Kits) protein levels, suggesting the alteration of the direct pathway. We developed a novel motor skill transfer test for mice and found deficits in Dyt1 KI mice.

  6. cellular and molecular framework for how impaired torsinA function selectively disrupts neural circuits and raise the possibility that discrete foci of neurodegeneration may contribute to the pathogenesis of DYT1 dystonia

  7. Results reveal subtle structural changes of the cerebellum that are similar to those reported for the basal ganglia in the DYT1 knock-in mouse model.

  8. the mutation only slightly increases the excitability of striatal GABAergic neurons in DYT1 dystonia.

  9. detected differences in spontaneous locomotion between aged torsinA(DeltaE) KI-Fbg1 (show FBXO2 ELISA Kits) knock out and control mice

  10. The substantia nigra expression of torsinA does not protect against experimental Parkinson's disease in mice.

Pig (Porcine) Torsin Family 1, Member A (Torsin A) (TOR1A) interaction partners

  1. This work reports the cloning and analysis of the porcine (Sus scrofa) homologue of TOR1A.

Torsin Family 1, Member A (Torsin A) (TOR1A) Antigen Profile

Antigen Summary

The protein encoded by this gene is a member of the AAA family of adenosine triphosphatases (ATPases), is related to the Clp protease/heat shock family and is expressed prominently in the substantia nigra pars compacta. Mutations in this gene result in the autosomal dominant disorder, torsion dystonia 1.

Gene names and symbols associated with TOR1A

  • torsin family 1, member A (Tor1a) antibody
  • torsin family 1, member A (torsin A) (TOR1A) antibody
  • torsin family 1, member A (torsin A) (Tor1a) antibody
  • DQ2 antibody
  • DYT1 antibody
  • torsinA antibody

Protein level used designations for TOR1A

dystonia 1, torsion (autosomal dominant , dystonia 1, torsion (autosomal dominant; torsin A) , torsin A , torsin-1A , dystonia 1 protein , torsin family 1 member A

GENE ID SPECIES
266606 Rattus norvegicus
1861 Homo sapiens
30931 Mus musculus
100125953 Sus scrofa
533699 Bos taurus
Did you look for something else?