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anti-Tousled-Like Kinase 1 (TLK1) Antibodies

The protein encoded by TLK1 is a serine/threonine kinase that may be involved in the regulation of chromatin assembly. Additionally we are shipping Tousled-Like Kinase 1 Proteins (6) and Tousled-Like Kinase 1 Kits (1) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
TLK1 9874 Q9UKI8
TLK1 228012 Q8C0V0
TLK1 311118  
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Top anti-Tousled-Like Kinase 1 Antibodies at antibodies-online.com

Showing 10 out of 112 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Rabbit Un-conjugated WB WB Suggested Anti-TLK1 Antibody Titration: 0.2-1 ug/mlELISA Titer: 1:62500Positive Control: 721_B cell lysate 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Rabbit Un-conjugated EIA, IHC (p), WB 0.4 mL Log in to see 6 to 8 Days
$390.50
Details
Human Rabbit Un-conjugated IF, ELISA Immunofluorescence analysis of COS7 cells, using TLK1 (Ab-764) Antibody. The picture on the right is treated with the synthesized peptide. 100 μg Log in to see 2 to 3 Days
$302.50
Details
Human Rabbit Un-conjugated IHC (p), WB Western blot analysis of hTLK1-L687 (ABIN392685) in K562 cell line lysates (35 µg/lane). TLK1 (arrow) was detected using the purified polyclonal antibody. Formalin-fixed and paraffin-embedded human cancer tissue reacted with the primary antibody, which was peroxidase-conjugated to the secondary antibody, followed by AEC staining. BC = breast carcinoma. HC = hepatocarcinoma 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Rabbit Un-conjugated WB WB Suggested Anti-TLK1 Antibody Titration: 0.2-1 ug/mlELISA Titer: 1:312500Positive Control: ACHN cell lysate WB Suggested Anti-TLK1  Antibody Titration: 0.2-1 µg/mL ELISA Titer: 1:.12500  Positive Control: ACHN cell lysate 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Rabbit Un-conjugated EIA Western blot using anti-Tlk-1 antibody shows detection of a band ~64 kDa corresponding to isoform 3 of human Tlk-1 (arrowhead). Specific reactivity with this band is blocked when the antibody is preincubated with the immunizing peptide (data not shown). Approximately 30 ug of a HeLa nuclear extract was separated by SDS-PAGE and transferred onto nitrocellulose. After blocking the membrane was probed with the primary antibody diluted to 1:250 for 2h at room temperature followed by washes and reaction with a 1:10,000 dilution of RDye™800 conjugated Gt-a-Rabbit IgG [H&L] MX for 45 min at room temperature. IRDye™800 fluorescence image was captured using the Odyssey® Infrared Imaging System developed by LI-COR. IRDye is a trademark of LI-COR, Inc. Other detection systems will yield similar results. 0.1 mg Log in to see 6 to 8 Days
$500.50
Details
Human Rabbit Un-conjugated ELISA, WB   100 μg Log in to see 2 to 3 Days
$302.50
Details
Human Rabbit Un-conjugated ICC, IF, WB ICC/IF Image Immunofluorescence analysis of paraformaldehyde-fixed HeLa, using TLK1, antibody at 1:200 dilution. WB Image Sample(30 μg of whole cell lysate) A:293T 7.5% SDS PAGE antibody diluted at 1:500 100 μL Log in to see 2 to 3 Days
$358.60
Details
Mouse Rabbit Un-conjugated WB Mouse Tlk1 Antibody (C-term)  western blot analysis in mouse Neuro-2a cell line lysates (35ug/lane).This demonstrates the Tlk1 antibody detected the Tlk1 protein (arrow). 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Rabbit Un-conjugated WB Western blot analysis of TLK1 expression in HeLa (A), NIH3T3 (B), PC12 (C) whole cell lysates. 200 μL Log in to see 9 Days
$487.50
Details

TLK1 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
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Top referenced anti-Tousled-Like Kinase 1 Antibodies

  1. Human Polyclonal TLK1 Primary Antibody for EIA - ABIN117936 : Remy, Perney, Bourat, Ramos, Marty, Cabaniols, Durand, Quenet, Blanc: [Amyloidosis of the gallbladder. An unusual localization] in Gastroentérologie clinique et biologique 1995 (PubMed)
    Show all 8 references for ABIN117936

  2. Human Polyclonal TLK1 Primary Antibody for EIA, IHC (p) - ABIN360576 : Cabaniols, Ravichandran, Roche: Phosphorylation of SNAP-23 by the novel kinase SNAK regulates t-SNARE complex assembly. in Molecular biology of the cell 2000 (PubMed)
    Show all 4 references for ABIN360576

  3. Human Polyclonal TLK1 Primary Antibody for WB - ABIN2787642 : Ewing, Chu, Elisma, Li, Taylor, Climie, McBroom-Cerajewski, Robinson, OConnor, Li, Taylor, Dharsee, Ho, Heilbut, Moore, Zhang, Ornatsky, Bukhman, Ethier, Sheng, Vasilescu, Abu-Farha, Lambert, Duewel et al.: Large-scale mapping of human protein-protein interactions by mass spectrometry. ... in 2007 (PubMed)

  4. Human Polyclonal TLK1 Primary Antibody for ELISA, WB - ABIN1452102 : Yamakawa, Kameoka, Hashimoto, Yoshitake, Nishikawa, Tanihara, Date: cDNA cloning and chromosomal mapping of genes encoding novel protein kinases termed PKU-alpha and PKU-beta, which have nuclear localization signal. in Gene 1998 (PubMed)

  5. Human Polyclonal TLK1 Primary Antibody for IHC (p), WB - ABIN392685 : Takayama, Kokuryo, Yokoyama, Ito, Nagino, Hamaguchi, Senga: Silencing of Tousled-like kinase 1 sensitizes cholangiocarcinoma cells to cisplatin-induced apoptosis. in Cancer letters 2010 (PubMed)

More Antibodies against Tousled-Like Kinase 1 Interaction Partners

Caenorhabditis elegans (C. elegans) Tousled-Like Kinase 1 (TLK1) interaction partners

  1. TLK-1 contributes to chromosome condensation and segregation;TLK-1 functions in cytokinesis by localizing AIR-2 to the midzone microtubules.

  2. Tousled-like kinase (TLK-1) contributes to chromosome segregation as a substrate and regulator of the Aurora B kinase AIR-2.

Human Tousled-Like Kinase 1 (TLK1) interaction partners

  1. TLK1B mediated phosphorylation of Rad9 (show RAD9A Antibodies) regulates its nuclear/cytoplasmic localization and cell cycle checkpoint

  2. Data indicate Tousled-like kinases (TLK1) phosphorylation has an impact on cell cycle proteins Asf1a (show ASF1A Antibodies) and Asf1b (show ASF1B Antibodies) function.

  3. Tousled-like kinase-dependent phosphorylation of Rad9 (show RAD9A Antibodies) plays a role in cell cycle progression and G2/M checkpoint exit.

  4. Adenoviral delivery of Tousled kinase protects salivary glands against ionizing radiation damage.

  5. Silencing of TLK1 enhanced DNA damage induced by cisplatin treatment, suggesting that TLK1 plays a pivotal role for the repair of cisplatin-induced DNA damage.

  6. ASF1 (show SRSF1 Antibodies) cellular levels are tightly controlled by distinct pathways and provide a molecular mechanism for post-translational regulation of dASF1 (show SRSF1 Antibodies) and hASF1a (show ASF1A Antibodies) by TLK (show TLK2 Antibodies) kinases.

  7. we show that Chk1 (show CHEK1 Antibodies) is essential for the suppression of TLK (show TLK2 Antibodies) activity after replication block, but that ATR (show ANTXR1 Antibodies), Chk2 (show CHEK2 Antibodies) and BRCA1 are dispensable for TLK (show TLK2 Antibodies) suppression.

  8. Both eIF4E (show EIF4E Antibodies) and TLK1B are elevated in breast cancer specimens but not in benign breast specimens from noncancer patients. Degree of TLK1B elevation is correlated with degree of IF4E (show EIF4E2 Antibodies) overexpression.

  9. In addition, it could be demonstrated that increasing the Tlk1 activity in HT1080 (show CDC123 Antibodies) cells by forced Tlk1 overexpression leads to an increased phosphorylation of endogenous p68 (show ANXA6 Antibodies).

  10. Studies provide evidence for TLK1B-mediated phosphorylation of Asf1 (show SRSF1 Antibodies) triggering DNA repair.

Mouse (Murine) Tousled-Like Kinase 1 (TLK1) interaction partners

Tousled-Like Kinase 1 (TLK1) Antigen Profile

Protein Summary

The protein encoded by this gene is a serine/threonine kinase that may be involved in the regulation of chromatin assembly. The encoded protein is only active when it is phosphorylated, and this phosphorylation is cell cycle-dependent, with the maximal activity of this protein coming during S phase. The catalytic activity of this protein is diminished by DNA damage and by blockage of DNA replication. Three transcript variants encoding different isoforms have been found for this gene.

Gene names and symbols associated with TLK1

  • tousled-like kinase 1 (TLK1) antibody
  • tousled-like kinase 1b (tlk1b) antibody
  • tousled-like kinase 1 (LOC542181) antibody
  • tousled-like kinase 1 (tlk1) antibody
  • Protein TLK-1 (tlk-1) antibody
  • tousled-like kinase 1 (Tlk1) antibody
  • tousled-like kinase 1a (tlk1a) antibody
  • 4930545J15Rik antibody
  • DKFZp459L163 antibody
  • fb76h12 antibody
  • fe11e12 antibody
  • PKU-beta antibody
  • si:dkey-88m1.1 antibody
  • si:dkey-251e16.4 antibody
  • tlk1 antibody
  • wu:fb76h12 antibody
  • wu:fe11e12 antibody

Protein level used designations for TLK1

tousled-like kinase 1 , pKU-beta protein kinase , serine/threonine-protein kinase tousled-like 1-B , tousled-like kinase 1-B , SNARE protein kinase SNAK , serine threonine protein kinase , serine/threonine-protein kinase tousled-like 1

GENE ID SPECIES
281533 Bos taurus
326734 Danio rerio
429024 Gallus gallus
459729 Pan troglodytes
478795 Canis lupus familiaris
537517 Bos taurus
542181 Zea mays
100024843 Monodelphis domestica
100052963 Equus caballus
100144941 Xenopus (Silurana) tropicalis
100157412 Sus scrofa
100174001 Pongo abelii
100345497 Oryctolagus cuniculus
100554902 Anolis carolinensis
100591136 Nomascus leucogenys
176369 Caenorhabditis elegans
9874 Homo sapiens
228012 Mus musculus
311118 Rattus norvegicus
557765 Danio rerio
Selected quality suppliers for anti-Tousled-Like Kinase 1 (TLK1) Antibodies
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