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TECR encodes a multi-pass membrane protein that resides in the endoplasmic reticulum, and belongs to the steroid 5-alpha reductase family. Additionally we are shipping TECR Antibodies (36) and many more products for this protein.
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Data indicate that trans-2-enoyl-CoA reductase TER is involved in both very long-chain fatty acids (VLCFAs) synthesis and sphingosine degradation within sphingolipids.
P182L mutation reduces the activity and stability of the TECR enzyme.
Exome sequencing reveals a novel mutation for autosomal recessive non-syndromic mental retardation in the TECR gene on chromosome 19p13.
This gene encodes a multi-pass membrane protein that resides in the endoplasmic reticulum, and belongs to the steroid 5-alpha reductase family. The elongation of microsomal long and very long chain fatty acid consists of 4 sequential reactions. This protein catalyzes the final step, reducing trans-2,3-enoyl-CoA to saturated acyl-CoA. Alternatively spliced transcript variants have been found for this gene.
glycoprotein, synaptic 2
, synaptic glycoprotein SC2
, very-long-chain enoyl-CoA reductase
, neuroprotective protein 13
, trans-2,3-enoyl-CoA reductase