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anti-Transcobalamin II (TCN2) Antibodies

TCN2 encodes a member of the vitamin B12-binding protein family. Additionally we are shipping Transcobalamin II Kits (20) and Transcobalamin II Proteins (13) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
TCN2 21452 O88968
TCN2 64365 Q9R0D6
TCN2 6948 P20062
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Top anti-Transcobalamin II Antibodies at antibodies-online.com

Showing 10 out of 43 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Rabbit Un-conjugated WB 100 μL Log in to see 2 to 3 Days
$289.00
Details
Mouse Rabbit Un-conjugated ELISA   100 μg Log in to see 20 to 21 Days
$163.90
Details
Cow Rabbit Un-conjugated WB 50 μg Log in to see 7 to 9 Days
$551.83
Details
Human Rabbit Un-conjugated IHC, WB Western blot analysis of extracts of various cell lines, using TCN2 antibody. Immunohistochemistry of paraffin-embedded Mouse brain using TCN2 antibody at dilution of 1:100 (x400 lens). 100 μL Log in to see 14 Days
$323.13
Details
Human Mouse Un-conjugated ELISA, WB Detection limit for recombinant GST tagged TCN2 is 1 ng/ml as a capture antibody. Western Blot analysis of TCN2 expression in transfected 293T cell line by TCN2 monoclonal antibody (M01), clone 2F4.Lane 1: TCN2 transfected lysate (Predicted MW: 47.5 KDa).Lane 2: Non-transfected lysate. 100 μg Log in to see 9 Days
$430.00
Details
Mouse Rabbit Un-conjugated WB Western Blot: Transcobalamin II Antibody [NBP1-74220] - Mouse Pancreas Lysate 1.0 ug/ml, gel concentration 12% 100 μL Log in to see 6 to 9 Days
$447.56
Details
Mouse Rabbit Un-conjugated ELISA   100 μg Log in to see 20 to 21 Days
$273.90
Details
Human Rabbit HRP IHC (p), WB   100 μL Log in to see 14 to 21 Days
$405.90
Details
Human Mouse Un-conjugated ELISA, WB   100 μg Log in to see 7 to 9 Days
$537.17
Details
Human Rabbit Un-conjugated IHC, WB Western blot analysis of extracts of various cell lines, using TCN2 antibody. 200 μL Log in to see 8 to 9 Days
$588.50
Details

TCN2 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
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Top referenced anti-Transcobalamin II Antibodies

  1. Mouse (Murine) Polyclonal TCN2 Primary Antibody for ELISA - ABIN2001335 : Seetharam, Li: Transcobalamin II and its cell surface receptor. in Vitamins and hormones 2000 (PubMed)

More Antibodies against Transcobalamin II Interaction Partners

Human Transcobalamin II (TCN2) interaction partners

  1. The association of the TCN2 polymorphism with peripheral neuropathy was independent of vitamin B-12 intake.

  2. G/G homozygosity of C776G TC2 and the C/G genotype of the C776G TC2 genegene polymorphism increases the risk of oral cancer

  3. The mutation does not seem to interfere with the function of TC, but the mutation may well explain the low level of holoTC detected by the Abbott assay. The results underscores that mutations of TCN2 have to be considered when implausible holoTC results are obtained.

  4. 4 patients with transcobalamin II deficiency were found to have novel mutations, of whom 2 had the same large deletion (homozygous c.1106+1516-1222+1231del). One had c.1107- 347_1222+981delin 364. Another had homozygous c.106C>T. (Q36X).

  5. There were no other associations between single -nucleotide polymorphisms and the efficacy of MTX (show MTX1 Antibodies) treatment. CONCLUSIONS: The MTHFR (show MTHFR Antibodies) 677CC and GGH (show GGH Antibodies) 401TT and CT genotypes were associated with a reduction in the number of MTX (show MTX1 Antibodies)-related adverse events.

  6. Report TCN2 mutations causing transcobalamin deficiency in an Indian patient.

  7. Although not significant when corrected for multiple testing, eight single nucleotide polymorphisms (SNPs) in two genes, transcobalamin II (TCN2) and the transcobalamin II-receptor (TCblR (show CD320 Antibodies)), were found to influence several clinical traits of cobalamin deficiency.

  8. In Asian populations, the investigated polymorphisms mapping at TCN2 and CBS (show CBS Antibodies) genes did not provide any evidence of association with cleft lip/cleftpalate.

  9. TCN2 776C --> G polymorphism is negatively associated with Alzheimer's type dementia, suggesting a protective role against the disease in subjects with the 5, 10-methylenetetrahydrofolate reductase (show MTHFR Antibodies) 1298AA genotype

  10. Transcobalamin II (TCN2 67A>G and TCN2 776C>G) and transcobalamin II receptor (TCblR (show CD320 Antibodies) 1104C>T) polymorphisms in Korean patients with idiopathic recurrent spontaneous abortion

Cow (Bovine) Transcobalamin II (TCN2) interaction partners

  1. study investigated crystallographically the beta-ligand exchange on Cbl bound to transcobalamin (TC) by crystallization of bovine holo-TC in the presence of either cyanide or sulfite

Transcobalamin II (TCN2) Antigen Profile

Protein Summary

This gene encodes a member of the vitamin B12-binding protein family. This family of proteins, alternatively referred to as R binders, is expressed in various tissues and secretions. This plasma protein binds cobalamin and mediates the transport of cobalamin into cells. This protein and other mammalian cobalamin-binding proteins, such as transcobalamin I and gastric intrisic factor, may have evolved by duplication of a common ancestral gene. Alternative splicing results in multiple transcript variants.

Gene names and symbols associated with TCN2

  • transcobalamin 2 (Tcn2) antibody
  • transcobalamin II (TCN2) antibody
  • AW208754 antibody
  • D22S676 antibody
  • D22S750 antibody
  • II antibody
  • TC antibody
  • TC-2 antibody
  • TC2 antibody
  • TCII antibody
  • TC II antibody
  • Tcn-2 antibody
  • Tcn2p antibody

Protein level used designations for TCN2

TC II , TC-2 , TCII , transcobalamin II , transcobalamin-2 , macrocytic anemia , transcobalamin II; macrocytic anemia , vitamin B12-binding protein 2

GENE ID SPECIES
21452 Mus musculus
64365 Rattus norvegicus
6948 Homo sapiens
281518 Bos taurus
100171681 Pongo abelii
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