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Necessary for efficient RNA polymerase II transcription elongation past template-encoded arresting sites. Additionally we are shipping TCEA1 Antibodies (58) and TCEA1 Proteins (8) and many more products for this protein.
RNF20 (show RNF20 ELISA Kits), presumably via H2Bub, selectively represses oncogenic genes by interfering with chromatin recruitment of TFIIS, a factor capable of relieving stalled RNA polymerase II. RNF20 (show RNF20 ELISA Kits) inhibits the interaction between TFIIS and the PAF1 (show PEX2 ELISA Kits) complex.
a role for TFIIS in transcription recovery and re-establishment of the balance between hypo- and hyper-phosphorylated RNAPII after DNA damage repair
Results indicate that TFIIS is not limiting for the repair of transcription-blocking DNA lesions and thus the present work does not support a role for TFIIS in TC-NER (show NR1H2 ELISA Kits).
Results provide a model of the RNA polymerase II-transcription elongation factor (show TSFM ELISA Kits) TFIIS complex from X-ray diffraction data to 3.8 A resolution.
transcription factor IIF, hepatitis delta antigen, and stimulatory factor II control human RNA polymerase II (RNAP II) pausing and transcript cleavage
TFIIS has a role in suppression of transient pausing, which is the most important contribution of TFIIS to elongation from a stall position
Data shpw that SII is a major component of chromatin transcription and strongly synergizes with p300 (show EP300 ELISA Kits) (histone acetylation) at a step subsequent to preinitiation complex formation.
PLAG1 (show PLAG1 ELISA Kits) protein is overexpressed in epithelial, myoepithelial, and mesenchymal-like tumor cells in tumors with fusions to CHCHD7 and TCEA1.
Necessary for efficient RNA polymerase II transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by S-II allows the resumption of elongation from the new 3'-terminus.
transcription elongation factor A (SII), 1
, transcription elongation factor A 1
, transcription elongation factor A protein 1
, transcription elongation factor S-II protein 1
, transcription elongation factor TFIIS.o