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Necessary for efficient RNA polymerase II transcription elongation past template-encoded arresting sites. Additionally we are shipping Transcription Elongation Factor A (SII), 3 Proteins (6) and many more products for this protein.
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Human Polyclonal TCEA3 Primary Antibody for EIA, WB - ABIN955122
Kim, Guermah, Roeder: The human PAF1 complex acts in chromatin transcription elongation both independently and cooperatively with SII/TFIIS. in Cell 2010
Show all 4 references for 955122
Cow (Bovine) Polyclonal TCEA3 Primary Antibody for WB - ABIN2777922
Labhart, Morgan: Identification of novel genes encoding transcription elongation factor TFIIS (TCEA) in vertebrates: conservation of three distinct TFIIS isoforms in frog, mouse, and human. in Genomics 1998
Findings reveal a novel mechanism by which p53 (show TP53 Antibodies) utilizes TFIIS.h to selectively promote the transcriptional elongation of the bax (show BAX Antibodies) gene, upsurging cell death in response to severe DNA damage.
TCEA3 attenuates the proliferation and induces apoptosis of gastric cancer cells
Tcea3 binds to TGF-beta (show TGFB1 Antibodies) I receptor and activates TGF-beta (show TGFB1 Antibodies) signaling pathway.
Study demonstrates a strong synergy between hPAF1C and elongation factor (show TSFM Antibodies) SII/TFIIS (show TCEA1 Antibodies) and an underlying mechanism involving direct hPAF1C-SII (show TCEA1 Antibodies) interactions and cooperative binding to RNA polymerase II.
Our results indicated, for the first time, that TCEA3 promotes the differentiation of bovine MDSCs and have implications for meat production and animal rearing.
Vascular endothelial growth factor A (show VEGFA Antibodies) and VEGFC (show VEGFC Antibodies), major transcription factors that regulate vasculogenesis, are activated in Tcea3 knocked down mESCs
Tcea3 critically regulates pluripotent differentiation of mouse embryonic stem cells as a molecular rheostat of Lefty1 (show LEFTY1 Antibodies)-Nodal-Smad2 (show SMAD2 Antibodies) signaling.
S-II (show TCEA1 Antibodies) is required for definitive hematopoiesis.
These results suggest that S-II (show TCEA1 Antibodies) is involved in transcription of the Bcl-x (show BCL2L1 Antibodies) and beta(major)-globin gene during erythroblast differentiation, by relieving transcription arrest or affecting histone modification on chromatin template.
Necessary for efficient RNA polymerase II transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by S-II allows the resumption of elongation from the new 3'-terminus.
transcription elongation factor A (SII), 3
, transcription elongation factor type xTFIIS.l
, transcription elongation factor A protein 3
, transcription elongation factor S-II
, transcription elongation factor XSII-K1
, rhabdomyosarcoma antigen MU-RMS-40.22
, transcription elongation factor S-II protein 3
, transcription elongation factor TFIIS.h
, tissue-specific transcription factor S-II