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The protein encoded by TCEA2 is found in the nucleus, where it functions as an SII class transcription elongation factor. Additionally we are shipping TCEA2 Proteins (12) and many more products for this protein.
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Cow (Bovine) Polyclonal TCEA2 Primary Antibody for WB - ABIN2777921
Sijbrandi, Fiedler, Timmers: RNA polymerase II complexes in the very early phase of transcription are not susceptible to TFIIS-induced exonucleolytic cleavage. in Nucleic acids research 2002
RNA polymerase II complexes in the very early phase of transcription are not susceptible to TFIIS (show TCEA1 Antibodies)-induced exonucleolytic cleavage.
data suggest that because TFIIS (show TCEA1 Antibodies) promotes escape from promoter-proximal pauses by stimulating cleavage of back-tracked nascent RNA, TFIIS (show TCEA1 Antibodies) inhibition may help DSIF (show SUPT5H Antibodies)/NELF (show NELF Antibodies) negatively regulate productive transcription
SII is important for preventing cellular death due to oxidative DNA damage, assisting RNAPII to bypass 8-oxoG
The protein encoded by this gene is found in the nucleus, where it functions as an SII class transcription elongation factor. Elongation factors in this class are responsible for releasing RNA polymerase II ternary complexes from transcriptional arrest at template-encoded arresting sites. The encoded protein has been shown to interact with general transcription factor IIB, a basal transcription factor. Two transcript variants encoding different isoforms have been found for this gene.
transcription elongation factor A protein 2
, testis-specific S-II
, transcription elongation factor S-II protein 2
, transcription elongation factor TFIIS.1
, transcription elongation factor TFIIS.l
, transcription elongation factor A2