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Transcription Factor 12 (TCF12) ELISA Kits

The protein encoded by TCF12 is a member of the basic helix-loop-helix (bHLH) E-protein family that recognizes the consensus binding site (E-box) CANNTG. Additionally we are shipping TCF12 Antibodies (83) and TCF12 Proteins (7) and many more products for this protein.

list all ELISA KIts Gene Name GeneID UniProt
TCF12 6938 Q99081
Anti-Mouse TCF12 TCF12 21406 Q61286
TCF12 25720 P51514
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Top TCF12 ELISA Kits at antibodies-online.com

Showing 2 out of 2 products:

Catalog No. Reactivity Sensitivity Range Quantity Supplier Delivery Price Details
Human
96 Tests Log in to see 16 to 21 Days
$999.43
Details
Rat
96 Tests Log in to see 16 to 21 Days
$999.43
Details

More ELISA Kits for TCF12 Interaction Partners

Human Transcription Factor 12 (TCF12) interaction partners

  1. Two novel translocations leading to the inactivation of RUNX1 (show RUNX1 ELISA Kits) and its partners SIN3A and TCF12 in myeloid leukemia (show BCL11A ELISA Kits).

  2. Studies suggest that transcription factor 12 (TCF12) should be included in level 2 genetic testing.

  3. show that these mutations compromise TCF12 transcriptional activity and are associated with a more aggressive tumour type

  4. several familial cases of coronal synostosis associated with mutations in TCF12

  5. In t(8;21) leukemia cells, the two E proteins, HEB and E2A (show TCF3 ELISA Kits), function as components of the stable AML1 (show RUNX1 ELISA Kits)-ETO (show RUNX1T1 ELISA Kits)-containing transcription factor complex (AETFC). The AETFC components cooperatively regulate gene expression and contribute to leukemogenesis.

  6. haploinsufficiency of TCF12 causes coronal synostosis in humans and that severe bilateral coronal synostosis occ (show TWIST1 ELISA Kits)urs in mice with 50% of the wild-type dosage of both the T (show TWIST1 ELISA Kits)cf12 and Twist1 genes highlights the key role of TCF12 acting with TWIST1.

  7. the CD91 (show LRP1 ELISA Kits)/IKK (show CHUK ELISA Kits)/NF-kappaB (show NFKB1 ELISA Kits) signaling cascade is involved in secreted HSP90alpha-induced TCF12 expression, leading to E-cadherin (show CDH1 ELISA Kits) down-regulation and enhanced CRC (show CALR ELISA Kits) cell migration/invasion

  8. TCF12 functioned as a transcriptional repressor of E-cadherin (show CDH1 ELISA Kits) and its overexpression was significantly correlated with the occurrence of CRC (show CALR ELISA Kits) metastasis.

  9. HEB and E2A (show TCF3 ELISA Kits)-bind the SCA motif at regions overlapping SMAD2 (show SMAD2 ELISA Kits)/3 and FOXH1 (show FOXH1 ELISA Kits)

  10. As a first exploitation of this unique cohort, we identify three novel candidate dyslexia genes, ZNF280D and TCF12 at 15q21, and PDE7B at 6q23.3, by molecular mapping of the familial translocation with the 15q21 breakpoint.

Mouse (Murine) Transcription Factor 12 (TCF12) interaction partners

  1. HEB (show FREM1 ELISA Kits) is a fundamental link between Nodal signalling, the derepression of a specific class of poised promoters during differentiation, and lineage specification in mouse embryonic stem cells

  2. severe bilateral coronal synostosis occurs in mice with 50% of the wild-type dosage of both the Tcf12 and Twist1 (show TWIST1 ELISA Kits) genes highlights the key role of TCF12 acting with TWIST1 (show TWIST1 ELISA Kits) in the normal development of the coronal sutures

  3. Deficiency in the E proteins, E2A (show TCF3 ELISA Kits) and HEB (show FREM1 ELISA Kits), led to increased frequency of terminally differentiated effector KLRG1 (show KLRG1 ELISA Kits)(hi) CD8 (show CD8A ELISA Kits)(+) T cells in mice during infection, and decreased generation of longer-lived memory-precursor cells during the immune response.

  4. Deletion of HEB (show FREM1 ELISA Kits) and E2A (show TCF3 ELISA Kits) in DP thymocytes specifically blocked the development of CD4 (show CD4 ELISA Kits)(+) lineage T cells. Furthermore, deletion of the E protein inhibitors Id2 and Id3 (show ID3 ELISA Kits) allowed CD4 (show CD4 ELISA Kits)(+) T cell development but blocked CD8 (show CD8A ELISA Kits)(+) lineage development.

  5. the earliest event in B-cell specification involves the induction of FOXO1 (show FOXO1 ELISA Kits) expression and requires the combined activities of E2A (show TCF3 ELISA Kits) and HEB (show FREM1 ELISA Kits)

  6. These results showed a new set of interactions between HEB (show FREM1 ELISA Kits), Notch1 (show NOTCH1 ELISA Kits), and GATA3 (show GATA3 ELISA Kits) that regulate the T-cell fate choice in developing thymocytes.

  7. Developmental progression of fetal HEB (show FREM1 ELISA Kits)(-/-) precursors to the pre-T-cell stage is restored by HEBAlt.

  8. HEB (show FREM1 ELISA Kits) is a specific and essential factor in T-cell development and in the generation of the iNKT cell lineage.

  9. the dosage of HEB (show FREM1 ELISA Kits) determines pT alpha (show PTCRA ELISA Kits) gene expression in immature T cells

  10. the Tcf12 gene may be involved in the control of proliferating neural stem cells and progenitor cells

TCF12 Antigen Profile

Antigen Summary

The protein encoded by this gene is a member of the basic helix-loop-helix (bHLH) E-protein family that recognizes the consensus binding site (E-box) CANNTG. This encoded protein is expressed in many tissues, among them skeletal muscle, thymus, B- and T-cells, and may participate in regulating lineage-specific gene expression through the formation of heterodimers with other bHLH E-proteins. Several alternatively spliced transcript variants of this gene have been described, but the full-length nature of some of these variants has not been determined.

Gene names and symbols associated with TCF12

  • transcription factor 12 (TCF12) antibody
  • transcription factor 12 (LOC100339415) antibody
  • transcription factor 12 (tcf12) antibody
  • transcription factor 12 (Tcf12) antibody
  • transcription factor 12 (HTF4, helix-loop-helix transcription factors 4) (tcf12) antibody
  • A130037E08Rik antibody
  • ALF1 antibody
  • bHLHb20 antibody
  • CRS3 antibody
  • HEB antibody
  • HEBAlt antibody
  • HsT17266 antibody
  • HTF-4 antibody
  • HTF4 antibody
  • ME1 antibody
  • REB antibody
  • SCBPA antibody
  • TCF12 antibody
  • wu:fb74g05 antibody
  • wu:fc43e06 antibody
  • zgc:85956 antibody
  • zgc:110341 antibody

Protein level used designations for TCF12

transcription factor 12 , transcription factor 12 (HTF4, helix-loop-helix transcription factors 4) , DNA-binding protein HTF4 , E-box-binding protein , TCF-12 , class B basic helix-loop-helix protein 20 , helix-loop-helix transcription factor 4 , transcription factor HTF-4 , class A helix-loop-helix transcription factor ME1 , SCBP alpha , SCBP-alpha , salivary-specific cAMP response element-binding protein alpha , TF12 , basic helix-loop-helix protein , class A helix-loop-helix transcription factor GE1 , XE1.1

GENE ID SPECIES
453466 Pan troglodytes
100339415 Oryctolagus cuniculus
100460448 Pongo abelii
100553875 Anolis carolinensis
100603993 Nomascus leucogenys
6938 Homo sapiens
509039 Bos taurus
21406 Mus musculus
25720 Rattus norvegicus
407985 Danio rerio
396334 Gallus gallus
100684199 Canis lupus familiaris
399451 Xenopus laevis
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