Transcription Factor B2, Mitochondrial Proteins (TFB2M)

S-adenosyl-L-methionine-dependent methyltransferase which specifically dimethylates mitochondrial 12S rRNA at the conserved stem loop. Additionally we are shipping TFB2M Antibodies (83) and TFB2M Kits (4) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
TFB2M 64216 Q9H5Q4
Rat TFB2M TFB2M 289307 Q5U2T7
TFB2M 15278 Q3TL26
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Top TFB2M Proteins at antibodies-online.com

Showing 7 out of 8 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
Insect Cells Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 50 Days
$5,442.50
Details
Insect Cells Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 50 Days
$5,442.50
Details
HOST_Escherichia coli (E. coli) Human His tag 50 μg Log in to see 15 to 19 Days
$319.00
Details
HOST_Wheat germ Human GST tag 2 μg Log in to see 11 to 12 Days
$333.33
Details
HOST_HEK-293 Cells Human Myc-DYKDDDDK Tag Validation with Western Blot 20 μg Log in to see 10 to 12 Days
$785.40
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Yeast Cow His tag   1 mg Log in to see 60 to 71 Days
$3,030.50
Details
HOST_Escherichia coli (E. coli) Human Un-conjugated   50 μg Log in to see 2 to 3 Days
$382.86
Details

TFB2M Proteins by Origin and Source

Origin Expressed in Conjugate
Human , , ,
, ,
Mouse (Murine)

More Proteins for Transcription Factor B2, Mitochondrial (TFB2M) Interaction Partners

Fruit Fly (Drosophila melanogaster) Transcription Factor B2, Mitochondrial (TFB2M) interaction partners

  1. These data demonstrate the essential role of TFB2M in mtDNA transcription, and reveal the complex cellular, biochemical, and molecular responses induced by impairment of oxidative phosphorylation during Drosophila development.

Human Transcription Factor B2, Mitochondrial (TFB2M) interaction partners

  1. demonstrate that a complex composed of TFAM (show TFAM Proteins) and POLRMT (show POLRMT Proteins) was readily formed at the promoter but alone was insufficient for promoter melting, which only occurred when TFB2M joined the complex

  2. The results reveal the organization of TFAM (show TFAM Proteins), POLRMT (show POLRMT Proteins) and TFB2M around the light-strand promoter and represent the first structural characterization of the entire mitochondrial transcriptional initiation complex.

  3. only two essential initiation factors, TFAM (show TFAM Proteins) and TFB2M, and two promoters, LSP and HSP1, are required to drive transcription of the mitochondrial genome

  4. The mRNA levels of TFB1M (show TFB1M Proteins) and TFB2M are influenced by endurance training

  5. Distinct, but possibly coordinated functions of mtTFB1 (show TFB1M Proteins) and mtTFB2 in mitochondrial gene expression and biogenesis.

  6. This study suggested that DNA variants in TFB2M did not contribute to the risk for parkinson disease.

  7. determined the variation in the TFAM (show TFAM Proteins), TFB1M (show TFB1M Proteins), and TFB2M genes in cardiac hypertrophy

  8. rRNA methyltransferase activity is necessary for induction of mitochondrial biogenesis by TFB1M (show TFB1M Proteins), but not TFB2M.

  9. Promoter-independent DNA conformation-dependent transcription required TFB2M.

Mouse (Murine) Transcription Factor B2, Mitochondrial (TFB2M) interaction partners

TFB2M Protein Profile

Protein Summary

S-adenosyl-L-methionine-dependent methyltransferase which specifically dimethylates mitochondrial 12S rRNA at the conserved stem loop. Also required for basal transcription of mitochondrial DNA, probably via its interaction with POLRMT and TFAM. Stimulates transcription independently of the methyltransferase activity (By similarity).

Gene names and symbols associated with TFB2M

  • mitochondrial transcription factor B2 (mtTFB2)
  • transcription factor B2, mitochondrial (TFB2M)
  • transcription factor B2, mitochondrial (tfb2m)
  • transcription factor B2, mitochondrial (LOC100346999)
  • transcription factor B2, mitochondrial (Tfb2m)
  • CG3910 protein
  • d-mtTFB2 protein
  • d-TF2BM protein
  • Dmel\\CG3910 protein
  • Hkp1 protein
  • mtTFB2 protein
  • sb:cb857 protein
  • TFB2 protein
  • TFB2M protein

Protein level used designations for TFB2M

CG3910-PA , mtTFB2-PA , transcription factor B2, mitochondrial , dimethyladenosine transferase 2, mitochondrial , HCV NS5A-transactivated protein 5 , S-adenosylmethionine-6-N', N'-adenosyl(rRNA) dimethyltransferase 2 , h-mtTFB , h-mtTFB2 , hTFB2M , hepatitis C virus NS5A-transactivated protein 5 , mitochondrial 12S rRNA dimethylase 2 , mitochondrial transcription factor B2 , mtTFB2 , house-keeping protein 1 , mTFB2M

GENE ID SPECIES
41228 Drosophila melanogaster
421488 Gallus gallus
457873 Pan troglodytes
480102 Canis lupus familiaris
569468 Danio rerio
703287 Macaca mulatta
100036660 Xenopus (Silurana) tropicalis
100346999 Oryctolagus cuniculus
100579942 Nomascus leucogenys
64216 Homo sapiens
289307 Rattus norvegicus
15278 Mus musculus
516874 Bos taurus
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