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Transcription Factor E3 (TFE3) ELISA Kits

The microphthalmia transcription factor/transcription factor E (MITF-TFE) family of basic helix-loop-helix leucine zipper (bHLH-Zip) transcription factors includes four family members: MITF, TFE3, TFEB and TFEC. Additionally we are shipping TFE3 Antibodies (103) and TFE3 Proteins (6) and many more products for this protein.

list all ELISA KIts Gene Name GeneID UniProt
TFE3 7030 P19532
Anti-Rat TFE3 TFE3 317376  
TFE3 209446 Q64092
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Top TFE3 ELISA Kits at antibodies-online.com

Showing 2 out of 5 products:

Catalog No. Reactivity Sensitivity Range Images Quantity Supplier Delivery Price Details
Human 0.118 ng/mL 0.31-20 ng/mL 96 Tests Log in to see 9 to 11 Days
$736.84
Details
Human
  96 Tests Log in to see 6 Days
$671.43
Details

More ELISA Kits for TFE3 Interaction Partners

Human Transcription Factor E3 (TFE3) interaction partners

  1. CT features including diameter, boundary, attenuation, nature, and circular calcification of the tumor, combined with demographic information and symptoms, may be useful to differentiate Xp11.2 RCC (show XRCC1 ELISA Kits) from different subtypes of PRCC (show PRCC ELISA Kits).

  2. TFEB and TFE3 are novel components of the integrated stress response

  3. validates the utility of TFE3 break-apart fluorescence in situ hybridization on formalin-fixed paraffin-embedded tissue sections for diagnosis and confirmation of Xp11.2 translocation RCCs and alveolar soft part sarcoma

  4. Studies indicate that alveolar soft part sarcoma showed a specific chromosomal alteration, der (show GDF3 ELISA Kits)(17)t(X:17)(p11 (show S100A10 ELISA Kits):q25), resulting in the fusion of the TFE3 transcription factor gene (Xp11) with alveolar soft part sarcoma critical region 1 (ASPSCR1 (show ASPSCR1 ELISA Kits)) at 17q25.

  5. TMED6-COG8 chimera might act as a novel diagnostic marker in TFE3 translocation renal cell carcinoma.

  6. We report a case of RCC (show XRCC1 ELISA Kits) with Xp11.2 translocation in a 17 year old boy who is a survivor of stage 4 neuroblastoma (show ARHGEF16 ELISA Kits) 13 years earlier.

  7. Case Report: renal carcinoma (show TSC2 ELISA Kits) associated with Xp11.2 translocations/ TFE3 gene fusions diagnosed using urine cytology.

  8. Renal cell carcinoma (RCC (show XRCC1 ELISA Kits)) associated with Xp11.2 translocation/TFE3 gene fusion (Xp11.2 RCC (show XRCC1 ELISA Kits)) was introduced as a genetically distinct entity into the World Health Organization classification of renal neoplasms in 2004.

  9. TFE3-GASE pathway is one of the regulatory pathways of the mammalian Golgi stress response

  10. PSF/SFPQ is a very common gene fusion partner in TFE3 rearrangement-associated perivascular epithelioid cell tumors (PEComas) and melanotic Xp11 translocation renal cancers.

Mouse (Murine) Transcription Factor E3 (TFE3) interaction partners

  1. TFEB and TFE3 are novel components of the integrated stress response

  2. Tfe3 is a critical transcription factor that regulates Pgc-1alpha (show PPARGC1A ELISA Kits) gene expression in myotubes

  3. A conditional expression in mice of the fusion gene ASPSCR1 (show ASPSCR1 ELISA Kits)-TFE3 from human alveolar soft part sarcoma (ASPS (show DARS ELISA Kits)) generated a model that recapitulates the human tumor histologically and by expression profile.

  4. Data from transgenic mice suggest Tfe3 controls lipid metabolism in adipose tissue (white, WAT; brown, BAT (show BAAT ELISA Kits)); TFE3 appears to be regulated by diet; up-regulation of TFE3 may inhibit expression of lipolysis genes in WAT and thermogenesis genes in BAT (show BAAT ELISA Kits).

  5. These findings indicated that TFE3 has a regulatory role in myoblast differentiation, and that transcriptional suppression of myogenin (show MYOG ELISA Kits) expression may be part of the mechanism of action.

  6. Machinery regulating exit of embryonic stem cells from pluripotency is ill defined; Flcn (show FLCN ELISA Kits) with its interaction partners Fnip1 (show FNIP1 ELISA Kits) and Fnip2 drives differentiation by restricting nuclear localization and activity of the bHLH transcription factor Tfe3.

  7. TFE3 and Galpha (show SUCLG1 ELISA Kits)(16) are up-regulated under pathologic conditions and are involved in a novel mechanism of transcriptional regulation via the relocalization and activation of Galpha (show SUCLG1 ELISA Kits)(16).

  8. FLCN (show FLCN ELISA Kits) tumor suppressor gene inactivation induces TFE3 transcriptional activity by increasing its nuclear localization

  9. TFE3 and TFEB regulate E-cadherin (show CDH1 ELISA Kits) and WT1 (show WT1 ELISA Kits) expression

  10. IRS2 (show IRS2 ELISA Kits), HK2 (show HK2 ELISA Kits) and INSIG1 (show INSIG1 ELISA Kits) are direct targets of TFE3

TFE3 Antigen Profile

Antigen Summary

The microphthalmia transcription factor/transcription factor E (MITF-TFE) family of basic helix-loop-helix leucine zipper (bHLH-Zip) transcription factors includes four family members: MITF, TFE3, TFEB and TFEC. The TEF3 protein encoded by this gene activates transcription through binding to the muE3 motif of the immunoglobulin heavy-chain enhancer. The TFEC protein forms heterodimers with the TEF3 protein and inhibits TFE3-dependent transcription activation. The TEF3 protein interacts with transcription regulators such as E2F3, SMAD3, and LEF-1, and is involved in TGF-beta-induced transcription, playing important roles in cell growth, proliferation, and osteoclast and macrophage differentiation. The TFE3 protein also activates hepatic IRS-2 gene, and induces hexokinase II (HK2) and insulin-induced gene 1 (INSIG1)\; it participates in insulin signaling and could be a therapeutic target for diabetes. This gene is also involved in chromosomal translocations, resulting in different fusion gene products in papillary renal cell carcinomas and alveolar soft part sarcomas, such as PRCC-TFE3, RCC17-TFE3, PSF-TFE3, NonO (p54nrb)-TFE3 and ASPL-TFE3.

Gene names and symbols associated with TFE3

  • transcription factor binding to IGHM enhancer 3 (TFE3) antibody
  • transcription factor binding to IGHM enhancer 3 (Tfe3) antibody
  • transcription factor binding to IGHM enhancer 3 (tfe3) antibody
  • transcription factor E3 (Tfe3) antibody
  • bHLHe33 antibody
  • F830016E06Rik antibody
  • RCCP2 antibody
  • RCCX1 antibody
  • RGD1559642 antibody
  • Tcfe3 antibody
  • Tfe-3 antibody
  • TFEA antibody

Protein level used designations for TFE3

class E basic helix-loop-helix protein 33 , transcription factor E family, member A , transcription factor E3 , transcription factor for IgH enhancer , transcription factor for immunoglobulin heavy-chain enhancer 3

GENE ID SPECIES
7030 Homo sapiens
491872 Canis lupus familiaris
520800 Bos taurus
317376 Rattus norvegicus
495043 Xenopus laevis
209446 Mus musculus
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