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Transcription Termination Factor, RNA Polymerase II Proteins (TTF2)

TTF2 encodes a member of the SWI2/SNF2 family of proteins, which play a critical role in altering protein-DNA interactions. Additionally we are shipping TTF2 Antibodies (33) and TTF2 Kits (3) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
TTF2 8458 Q9UNY4
TTF2 74044 Q5NC05
Rat TTF2 TTF2 295324  
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Top TTF2 Proteins at antibodies-online.com

Showing 3 out of 3 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 49 to 54 Days
$13,567.94
Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 49 to 54 Days
$13,567.94
Details
HOST_Wheat germ Human GST tag 10 μg Log in to see 9 Days
$405.71
Details

TTF2 Proteins by Origin and Source

Origin Expressed in Conjugate
Human ,
,
Mouse (Murine)

More Proteins for Transcription Termination Factor, RNA Polymerase II (TTF2) Interaction Partners

Human Transcription Termination Factor, RNA Polymerase II (TTF2) interaction partners

  1. Mutations of TTF2 (show FOXE1 Proteins) is associated with risk of Papillary Thyroid Cancer in Chinese. Patients with Multiplendular goiter and no metastasis are more likely to suffer PTC (show F9 Proteins). G/A mutation of TTF2 (show FOXE1 Proteins) had a high correlation with PTC (show F9 Proteins) in the overall population.

  2. hLodestar/HuF2 interacts with CDC5L (show CDC5L Proteins) and is involved in pre-mRNA splicing

  3. TTF2 is the only ATP-dependent termination activity associated with Pol II transcription elongation complexes, is largely unaffected by template position, and is impervious to the phosphorylation state of the polymerase.

  4. Importantly, the mitotic phenotype seen with TTF2-siRNA is rescued by expression of the siRNA-resistant GFP-tagged TTF2 proving that reduced TTF2 is responsible for the retention of RNA polymerase II on mitotic chromosomes.

Mouse (Murine) Transcription Termination Factor, RNA Polymerase II (TTF2) interaction partners

  1. Overexpression of TTF-2 during the palatogenesis may contribute to cleft palate.

TTF2 Protein Profile

Protein Summary

This gene encodes a member of the SWI2/SNF2 family of proteins, which play a critical role in altering protein-DNA interactions. The encoded protein has been shown to have dsDNA-dependent ATPase activity and RNA polymerase II termination activity. This protein interacts with cell division cycle 5-like, associates with human splicing complexes, and plays a role in pre-mRNA splicing.

Gene names and symbols associated with TTF2

  • transcription termination factor, RNA polymerase II (ttf2)
  • transcription termination factor, RNA polymerase II (TTF2)
  • transcription termination factor, RNA polymerase II (LOC100340161)
  • transcription termination factor, RNA polymerase II (Ttf2)
  • 4632434F22Rik protein
  • 8030447N19 protein
  • AV218430 protein
  • HuF2 protein
  • MGC81081 protein
  • TTF2 protein

Protein level used designations for TTF2

transcription termination factor, RNA polymerase II , transcription termination factor 2 , transcription termination factor 2-like , F2 , RNA polymerase II termination factor , human factor 2 , lodestar homolog , lodestar protein , transcription release factor 2

GENE ID SPECIES
431999 Xenopus laevis
457157 Pan troglodytes
531369 Bos taurus
100059720 Equus caballus
100340161 Oryctolagus cuniculus
100436073 Pongo abelii
100478679 Ailuropoda melanoleuca
100542156 Meleagris gallopavo
100600950 Nomascus leucogenys
8458 Homo sapiens
74044 Mus musculus
295324 Rattus norvegicus
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