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Many DNA-binding transcriptional activator proteins enhance the initiation rate of RNA polymerase II-mediated gene transcription by interacting functionally with the general transcription machinery bound at the basal promoter. Additionally we are shipping Transcriptional Adaptor 2A Antibodies (56) and many more products for this protein.
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Deficiency of ADA2 causes IgA-IgG antibody deficiencies in a family.
results thus demonstrate that the catalytic activity of GCN5 (show KAT2A Proteins) is stimulated by subunits of the ADA2a- or ADA2b (show TADA2B Proteins)-containing HAT (show MGEA5 Proteins) modules and is further increased by incorporation of the distinct HAT (show MGEA5 Proteins) modules in the ATAC (show XCL1 Proteins) or SAGA holo-complexes
Single nucleotide polymorphism in ADA2 gene is associated with type 1 diabetes.
CCDC134 increased the PCAF (show KAT2B Proteins)-dependent K320 acetylation of p53 (show TP53 Proteins) and p53 (show TP53 Proteins) protein stability in the presence of hADA2a overexpression.
hADA2a and hADA3 (show TADA3 Proteins) as crucial cofactors of beta-catenin (show CTNNB1 Proteins) that are likely involved in the assembly of transactivation-competent beta-catenin (show CTNNB1 Proteins) complexes at Wnt (show WNT2 Proteins) target genes.
Many DNA-binding transcriptional activator proteins enhance the initiation rate of RNA polymerase II-mediated gene transcription by interacting functionally with the general transcription machinery bound at the basal promoter. Adaptor proteins are usually required for this activation, possibly to acetylate and destabilize nucleosomes, thereby relieving chromatin constraints at the promoter. The protein encoded by this gene is a transcriptional activator adaptor and has been found to be part of the PCAF histone acetylase complex. Several alternatively spliced transcript variants encoding different isoforms of this gene have been described, but the full-length nature of some of these variants has not been determined.
transcriptional adaptor 2A
, transcriptional adaptor 2 (ADA2 homolog, yeast)-like
, transcriptional adapter 2-alpha-like
, ADA2-like protein
, transcriptional adapter 2-alpha
, transcriptional adaptor 2 alpha