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Transcriptional Adaptor 3 Proteins (TADA3)

Many DNA-binding transcriptional activator proteins enhance the initiation rate of RNA polymerase II-mediated gene transcription by interacting functionally with the general transcription machinery bound at the basal promoter. Additionally we are shipping Transcriptional Adaptor 3 Antibodies (73) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
TADA3 10474 O75528
TADA3 101206 Q8R0L9
TADA3 362414 Q4V8F5
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Top Transcriptional Adaptor 3 Proteins at antibodies-online.com

Showing 10 out of 12 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Escherichia coli (E. coli) Human GST tag 50 μg Log in to see 21 to 26 Days
$341.00
Details
HOST_Escherichia coli (E. coli) Human GST tag Transcriptional Adaptor 3 (TADA3) (AA 1-238), (partial) protein (GST tag) 1 mg Log in to see 56 to 66 Days
$1,842.50
Details
HOST_Wheat germ Human GST tag 10 μg Log in to see 9 Days
$405.71
Details
Yeast Cow His tag   1 mg Log in to see 56 to 66 Days
$3,206.50
Details
Yeast Rat His tag   1 mg Log in to see 56 to 66 Days
$3,206.50
Details
HOST_Escherichia coli (E. coli) Human Un-conjugated   50 μg Log in to see 3 to 4 Days
$388.93
Details
HOST_Escherichia coli (E. coli) Human Un-conjugated   50 μg Log in to see 16 to 21 Days
$314.29
Details
HOST_Human Human Un-conjugated   20 μg Log in to see 9 to 11 Days
$785.40
Details

TADA3 Proteins by Origin and Source

Origin Expressed in Conjugate
Human , ,
,
Mouse (Murine)

Rat (Rattus)

More Proteins for Transcriptional Adaptor 3 (TADA3) Interaction Partners

Human Transcriptional Adaptor 3 (TADA3) interaction partners

  1. results thus demonstrate that the catalytic activity of GCN5 (show KAT2A Proteins) is stimulated by subunits of the ADA2a (show TADA2A Proteins)- or ADA2b (show TADA2B Proteins)-containing HAT (show MGEA5 Proteins) modules and is further increased by incorporation of the distinct HAT (show MGEA5 Proteins) modules in the ATAC (show XCL1 Proteins) or SAGA holo-complexes

  2. PCAF (show KAT2B Proteins) and ADA3 regulate Bid (show BID Proteins) processing via PACS2 (show PACS2 Proteins), to modulate the mitochondrial cell death pathway in response to hGrzB.

  3. Cytoplasmic localization of alteration/deficiency in activation 3 (ADA3) predicts poor clinical outcome in breast cancer patients.

  4. Expression of the interacting proteins altered expression of an hADA3-regulated reporter gene, suggesting functional consequences for the interactions.

  5. a critical role of Ada3 in embryogenesis and cell cycle progression as an essential component of HAT complex.

  6. hADA3 interacts directly with RARalpha (show RARA Proteins) in a hormone-dependent manner and this interaction contributes to RARalpha (show RARA Proteins) transactivation

  7. Data identify hADA3, human homologue of the yeast transcriptional coactivator yADA3, as a novel human papillomavirus oncoprotein E6-interacting protein and a target of E6-induced degradation.

  8. Results demonstrate that human papilloma virus 16 E6 oncoprotein inhibits the RXR(alpha)-mediated transactivation of target genes, implying that perturbation of RXR-mediated transactivation by E6 could contribute to HPV oncogenesis.

  9. results demonstrate that transcriptional adaptor ADA3 protein directly binds to human estrogen receptor alpha (show ESR1 Proteins) and beta and enhances the transcription of estrogen receptor (show ESR1 Proteins)-responsive genes

  10. human Ada3 has an essential role in p53 (show TP53 Proteins) acetylation

Mouse (Murine) Transcriptional Adaptor 3 (TADA3) interaction partners

  1. demonstrate a novel ADA3 interaction with CENP-B (show CENPB Proteins)-centromere that may account for its previously known function in mitosis

  2. The loss of Ada3 led to enhanced chromosomal aberrations, such as chromosome breaks, fragments, deletions and translocations, which further increased upon DNA damage.

  3. a critical role of Ada3 in embryogenesis and cell cycle progression as an essential component of HAT complex.

Transcriptional Adaptor 3 (TADA3) Protein Profile

Protein Summary

Many DNA-binding transcriptional activator proteins enhance the initiation rate of RNA polymerase II-mediated gene transcription by interacting functionally with the general transcription machinery bound at the basal promoter. Adaptor proteins are usually required for this activation, possibly to acetylate and destabilize nucleosomes, thereby relieving chromatin constraints at the promoter. The protein encoded by this gene is a transcriptional activator adaptor and has been found to be part of the PCAF histone acetylase complex. In addition, it associates with the tumor suppressor protein p53 and is required for full activity of p53 and p53-mediated apoptosis. At least four alternatively spliced variants have been found for this gene, but the full-length nature of some variants has not been determined.

Gene names and symbols associated with TADA3

  • transcriptional adaptor 3 (LOC732883)
  • transcriptional adapter 3-like (LOC100061462)
  • transcriptional adapter 3-like (LOC100062412)
  • transcriptional adaptor 3 (TADA3)
  • transcriptional adapter 3-like (LOC100471385)
  • transcriptional adapter 3-like (LOC100542911)
  • transcriptional adapter 3-like (LOC100565624)
  • transcriptional adapter 3-like (LOC100619707)
  • transcriptional adaptor 3 (tada3-b)
  • transcriptional adaptor 3 (Tada3)
  • transcriptional adaptor 3 (NGG1 homolog, yeast)-like (tada3l)
  • 1110004B19Rik protein
  • ADA3 protein
  • ada3-B protein
  • AI987856 protein
  • fa03f04 protein
  • hADA3 protein
  • NGG1 protein
  • STAF54 protein
  • tada3 protein
  • Tada3l protein
  • tada3l-B protein
  • wu:fa03f04 protein
  • zgc:63596 protein

Protein level used designations for TADA3

transcriptional adaptor 3 , transcriptional adapter 3-like , ADA3 homolog B , ADA3-like protein B , Transcriptional adapter 3-like B , transcriptional adapter 3-B , ADA3 homolog , ADA3-like protein , transcriptional adapter 3 , mADA3

GENE ID SPECIES
732883 Bombyx mori
100061462 Equus caballus
100062412 Equus caballus
100157464 Sus scrofa
100471385 Ailuropoda melanoleuca
100542911 Meleagris gallopavo
100565624 Anolis carolinensis
100619707 Monodelphis domestica
447539 Xenopus laevis
416050 Gallus gallus
10474 Homo sapiens
476541 Canis lupus familiaris
510184 Bos taurus
101206 Mus musculus
362414 Rattus norvegicus
334785 Danio rerio
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