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TRERF1 encodes a zinc-finger transcriptional regulating protein which interacts with CBP/p300 to regulate the human gene CYP11A1. Additionally we are shipping Transcriptional Regulating Factor 1 Proteins (3) and Transcriptional Regulating Factor 1 Kits (2) and many more products for this protein.
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Human Polyclonal TRERF1 Primary Antibody for EIA, FACS - ABIN955327
Gizard, Robillard, Gross, Barbier, Révillion, Peyrat, Torpier, Hum, Staels: TReP-132 is a novel progesterone receptor coactivator required for the inhibition of breast cancer cell growth and enhancement of differentiation by progesterone. in Molecular and cellular biology 2006
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TReP-132 plays a role in regulating p450scc (show CYP11A1 Antibodies) expression with steroidogenic factor-1 (show NR5A1 Antibodies) and CBP/p300 (show CREBBP Antibodies)
TReP-132 interacts with steroidogenic factor-1 (SF-1 (show NR5A1 Antibodies)) through specific domains; and along with the interaction with CBP/p300 (show CREBBP Antibodies) these factors are postulated to form a complex to regulate expression of the P450scc (show CYP11A1 Antibodies) gene.
TReP-132 is a trans-acting factor of genes involved in adrenal glucocorticoid, C(19) steroid and estrogen production.
TReP-132 is a basal cell cycle regulatory protein (show RCC1 Antibodies) interacting with Sp1 (show PSG1 Antibodies) to activate the p21 (show CDKN1A Antibodies) and p27 (show PAK2 Antibodies) gene promoters.
identify TReP-132 as a coactivator of progesterone receptor (show PGR Antibodies) mediating the growth-inhibitory and differentiation effects of progesterone on breast cancer cells
cloning and characterization; expression of both mTReP-132 and P450scc (show CYP11A1 Antibodies) provides anatomical evidence that mTReP-132 may regulate this key steroidogenic enzyme within specific regions of the brain involved in behavioral and psychiatric disorders
This gene encodes a zinc-finger transcriptional regulating protein which interacts with CBP/p300 to regulate the human gene CYP11A1.
transcriptional regulating factor 1
, breast cancer anti-estrogen resistance 2
, transcriptional regulating protein 132
, transcriptional-regulating factor 1
, transcriptional-regulating protein 132
, zinc finger protein rapa
, zinc finger transcription factor TReP-132