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anti-Transducer of ERBB2, 2 (TOB2) Antibodies

TOB2 belongs to the TOB (see TOB1\\\\; MIM 605523)\\/BTG1 (MIM 109580) family of antiproliferative proteins, which are involved in the regulation of cell cycle progression.[supplied by OMIM, Apr 2004].. Additionally we are shipping Transducer of ERBB2, 2 Proteins (4) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
Anti-Rat TOB2 TOB2 315159  
TOB2 10766 Q14106
Anti-Mouse TOB2 TOB2 57259 Q9JM55
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Top anti-Transducer of ERBB2, 2 Antibodies at antibodies-online.com

Showing 10 out of 32 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Rabbit Un-conjugated EIA, IHC (p) 0.4 mL Log in to see 6 to 8 Days
$390.50
Details
Human Rabbit Un-conjugated IHC (p), WB Western blot analysis of TOB2 Antibody (N-term) (ABIN390219) in HepG2 cell line lysates (35 µg/lane). TOB2 (arrow) was detected using the purified polyclonal antibody. Formalin-fixed and paraffin-embedded human lung carcinoma tissue reacted with TOB2 antibody (N-term)(ABIN390219), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Rabbit Un-conjugated WB 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Rabbit Un-conjugated WB 100 μg Log in to see 8 to 10 Days
$507.83
Details
Human Rabbit Alkaline Phosphatase (AP) IHC, ELISA, WB   200 μL Log in to see 8 to 10 Days
$969.83
Details
Human Mouse Un-conjugated ELISA, WB Western Blot analysis of TOB2 expression in transfected 293T cell line by TOB2 monoclonal antibody (M01), clone 2F2-1A7.Lane 1: TOB2 transfected lysate(36.6 KDa).Lane 2: Non-transfected lysate. Detection limit for recombinant GST tagged TOB2 is 0.3 ng/ml as a capture antibody. 100 μg Log in to see 9 Days
$430.00
Details
Human Rabbit Un-conjugated WB   50 μg Log in to see 8 to 10 Days
$551.83
Details
Human Rabbit Un-conjugated ELISA   200 μL Log in to see 8 to 10 Days
$713.17
Details
Human Mouse Un-conjugated ELISA, WB Western Blot detection against Immunogen (63.95 KDa) . 50 μL Log in to see 9 Days
$298.57
Details
Human Rabbit Un-conjugated IHC, ELISA, WB   200 μL Log in to see 11 to 16 Days
$532.71
Details

TOB2 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
Human , ,
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Top referenced anti-Transducer of ERBB2, 2 Antibodies

  1. Human Polyclonal TOB2 Primary Antibody for EIA, IHC (p) - ABIN358776 : Ikematsu, Yoshida, Kawamura-Tsuzuku, Ohsugi, Onda, Hirai, Fujimoto, Yamamoto: Tob2, a novel anti-proliferative Tob/BTG1 family member, associates with a component of the CCR4 transcriptional regulatory complex capable of binding cyclin-dependent kinases. in Oncogene 2000 (PubMed)
    Show all 4 references for ABIN358776

More Antibodies against Transducer of ERBB2, 2 Interaction Partners

Human Transducer of ERBB2, 2 (TOB2) interaction partners

  1. Results show reduced Tob2 expression in primary hepatocellular Carcinoma cells (HCC (show FAM126A Antibodies)) and that dysregulation of miR (show MLXIP Antibodies)-362 and Tob2 may contribute to HCC (show FAM126A Antibodies) malignancy.

  2. The antiproliferative and the mRNA deadenylation/decay-promoting effects of TOB1 and TOB2 proteins are linked.

  3. study identifies miR-378-TOB2-cyclin D1 as a functional module to mediate the cross talk between Myc and Ras signaling in cellular transformation

  4. TNFalpha (show TNF Antibodies) is able to transactivate ErbB-2 (show ERBB2 Antibodies) and use it as an obligatory downstream signaling molecule in the generation of mitogenic signals.

  5. Haploinsufficiency of the MLL (show MLL Antibodies) and TOB2 genes in lymphoid malignancy.

  6. Antiproliferative proteins of the BTG/Tob (show TDO2 Antibodies) family are degraded by the ubiquitin-proteasome system. the C-terminal regions are necessary and sufficient to control the stabilities of BTG1 (show BTG1 Antibodies), BTG2 (show BTG2 Antibodies), Tob (show TDO2 Antibodies), and Tob2 proteins.

Mouse (Murine) Transducer of ERBB2, 2 (TOB2) interaction partners

  1. Tob1(-/-), Tob2(-/-), and Tob1/2 double knockout (DKO, Tob1(-/-) & Tob2(-/-)) embryonic stem cells (ESCs (show NR2E3 Antibodies)) grew faster than wild type (WT) ESCs (show NR2E3 Antibodies) without losing pluripotency.

  2. miR (show MLXIP Antibodies)-322 and its target protein Tob2 modulate Osx (show SP7 Antibodies) mRNA stability

  3. Tob2 protein suppresses PPARgamma2 (show PPARG Antibodies) transcription by inhibiting BMP2 (show BMP2 Antibodies)-induced Smad1 (show SMAD1 Antibodies)/5 phosphorylation through its interaction with Smad6 (show SMAD6 Antibodies) and by sequestering C/EBPalpha (show CEBPA Antibodies) from the PPARgamma2 (show PPARG Antibodies) promoter.

  4. Tob2 negatively regulates formation of osteoclasts by suppressing RANKL (show TNFSF11 Antibodies) expression through its interaction with vitamin D receptor (show VDR Antibodies)

Transducer of ERBB2, 2 (TOB2) Antigen Profile

Protein Summary

TOB2 belongs to the TOB (see TOB1\; MIM 605523)/BTG1 (MIM 109580) family of antiproliferative proteins, which are involved in the regulation of cell cycle progression.

Gene names and symbols associated with TOB2

  • transducer of ERBB2, 2 (Tob2) antibody
  • transducer of ERBB2, 2 (TOB2) antibody
  • transducer of ERBB2, 2 (tob2) antibody
  • 2900090N22Rik antibody
  • 4930545K18Rik antibody
  • AV071822 antibody
  • mKIAA1663 antibody
  • tob2 antibody
  • TOB4 antibody
  • TOBL antibody
  • TROB2 antibody

Protein level used designations for TOB2

protein Tob2 , transducer of ERBB2, 2 , protein Tob4 , transducer of erbB-2 2

GENE ID SPECIES
315159 Rattus norvegicus
458865 Pan troglodytes
548967 Xenopus (Silurana) tropicalis
707216 Macaca mulatta
10766 Homo sapiens
417992 Gallus gallus
481233 Canis lupus familiaris
507934 Bos taurus
57259 Mus musculus
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