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TBL2 encodes a member of the beta-transducin protein family. Additionally we are shipping Transducin (Beta)-Like 2 Antibodies (46) and Transducin (Beta)-Like 2 Proteins (4) and many more products for this protein.
association of TBL2 with the 60S subunit was ER stress independent while the TBL2-PERK interaction occurred upon ER stress
TBL2 interacts with PERK (show EIF2AK3 ELISA Kits) via the N-terminus proximal region and also associates with eIF2a (show EIF2S1 ELISA Kits) via the WD40 domain (show DCAF12L2 ELISA Kits) thus modulating stress-signaling and cell survival during endoplasmic reticulum stress.
A TERE1 (show UBIAD1 ELISA Kits)-TBL2 complex likely functions in oxidative/nitrosative stress, lipid metabolism, and SXR (show NR1I2 ELISA Kits) signaling pathways in its role as a tumor suppressor.
Data show that SNPs associated with TG in normolipidemic samples, including APOA5 (show APOA5 ELISA Kits), TRIB1 (show TRIB1 ELISA Kits), TBL2, GCKR (show GCKR ELISA Kits), GALNT2 (show GALNT2 ELISA Kits) and ANGPTL3 (show ANGPTL3 ELISA Kits) were significantly associated with HLP (show CYP3A4 ELISA Kits) types 2B, 3, 4 and 5.
This gene encodes a member of the beta-transducin protein family. Most proteins of the beta-transducin family are involved in regulatory functions. This protein is possibly involved in some intracellular signaling pathway. This gene is deleted in Williams-Beuren syndrome, a developmental disorder caused by deletion of multiple genes at 7q11.23.
transducin (beta)-like 2
, transducin beta-like protein 2-like
, WS beta-transducin repeats protein
, Williams-Beuren syndrome chromosome region 13
, transducin beta-like protein 2