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TFR encodes a cell surface receptor necessary for cellular iron uptake by the process of receptor-mediated endocytosis. Additionally we are shipping Transferrin Receptor Kits (40) and Transferrin Receptor Proteins (17) and many more products for this protein.
Showing 10 out of 277 products:
Human Monoclonal TFR Primary Antibody for ELISA, WB - ABIN108500
Cotton F,Thiry P,Boeynaems J: Measurement of soluble transferrin receptor by immunoturbidimetry and immunonephelometry. in Clin Biochem 2000
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Human Monoclonal TFR Primary Antibody for IHC (fro), FACS - ABIN967201
Friden, Walus, Musso, Taylor, Malfroy, Starzyk: Anti-transferrin receptor antibody and antibody-drug conjugates cross the blood-brain barrier. in Proceedings of the National Academy of Sciences of the United States of America 1991
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Human Monoclonal TFR Primary Antibody for ICC, FACS - ABIN610201
Bijur, Jope: Proapoptotic stimuli induce nuclear accumulation of glycogen synthase kinase-3 beta. in The Journal of biological chemistry 2001
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Human Monoclonal TFR Primary Antibody for ICC, FACS - ABIN610202
Etienne-Manneville, Hall: Cdc42 regulates GSK-3beta and adenomatous polyposis coli to control cell polarity. in Nature 2003
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Human Monoclonal TFR Primary Antibody for IF, WB - ABIN968748
McClelland, Kühn, Ruddle: The human transferrin receptor gene: genomic organization, and the complete primary structure of the receptor deduced from a cDNA sequence. in Cell 1985
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Simian immunodeficiency virus Nef-induced inhibition of TfR (show TFRC Antibodies) endocytosis leads to the reduction of Transferrin (show Tf Antibodies) uptake and intracellular iron concentration and is accompanied by attenuated lentiviral replication in macrophages.
Mice lacking Tfr1 (show TFRC Antibodies) in the heart died in the second week of life and had cardiomegaly, poor cardiac function, failure of mitochondrial respiration, and ineffective mitophagy.
Transferrin Receptor 1 Facilitates Poliovirus Permeation of Mouse Brain Capillary Endothelial Cells.
Erythrocytic iron deficiency enhances susceptibility to Plasmodium chabaudi infection in mice carrying a missense mutation in tfr1 (show TFRC Antibodies).
Tfr1 (show TFRC Antibodies) has a role in homeostatic maintenance of the intestinal epithelium, acting through a role that is independent of its iron-uptake function
Analysis by qPCR showed changes in mRNA levels of iron-responsive genes, indicating moderately increased iron in the RPE (show RPE Antibodies) of 10-month HID mice.
characterization of erythropoiesis, iron status, and hepcidin (show HAMP Antibodies) expression in mice with global or hematopoietic cell-specific haploinsufficiency of transferrin receptor 1 provides initial supporting data for this model
high levels of TfRs such as those found on activated lymphocytes were found to be associated with decreased KLRG1 (show KLRG1 Antibodies) inhibitory function, indicating that TfRs may sequester KLRG1 (show KLRG1 Antibodies) from interacting with cadherins.
data further demonstrate that the inhibitory activity of KLRG1 (show KLRG1 Antibodies) is decreased in T cells expressing high levels of TfR (show TFRC Antibodies), indicating that association of KLRG1 (show KLRG1 Antibodies) with TfR (show TFRC Antibodies) hinders KLRG1 (show KLRG1 Antibodies)-mediated silencing.
high-affinity anti-TfR (show TFRC Antibodies) alters TfR (show TFRC Antibodies) trafficking, which dramatically impacts the capacity for TfR (show TFRC Antibodies) to mediate blood-brain barrier transcytosis
Data indicate increased levels of reactive oxygen species (ROS (show ROS1 Antibodies)) were detected in bone marrow nucleated cells (BMNC) that express CD71 (show TFRC Antibodies) in in NUP98 (show NUP98 Antibodies)-HOXD13 (show HOXD13 Antibodies) (NHD13) transgenic mice, a murine model for myelodysplastic syndromes (MDS (show MECOM Antibodies)).
This gene encodes a cell surface receptor necessary for cellular iron uptake by the process of receptor-mediated endocytosis. This receptor is required for erythropoiesis and neurologic development. Mice that are deficient in this receptor show impaired erythroid development and abnormal iron homeostasis.
transferrin receptor 1
, transferrin receptor protein 1
, mammary tumor virus receptor 1