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Transferrin Receptor (p90, CD71) Proteins (TFRC)

TFRC encodes a cell surface receptor necessary for cellular iron uptake by the process of receptor-mediated endocytosis. Additionally we are shipping Transferrin Receptor (p90, CD71) Antibodies (436) and Transferrin Receptor (p90, CD71) Kits (24) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
TFRC 22042 Q62351
TFRC 64678  
TFRC 7037 P02786
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Top Transferrin Receptor (p90, CD71) Proteins at antibodies-online.com

Showing 10 out of 27 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Human GST tag Transferrin Receptor (p90, CD71) (TFRC) (AA 94-754) protein (GST tag) 50 μg Log in to see 9 to 11 Days
$242.00
Details
HOST_Human Cells Human His tag 100 μg Log in to see 16 Days
$382.80
Details
HOST_Human Cells Cynomolgus His tag 100 μg Log in to see 16 Days
$382.80
Details
HOST_Human Cells Mouse His tag 100 μg Log in to see 16 Days
$437.80
Details
Insect Cells Mouse rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.25 mg Log in to see 59 to 64 Days
$6,052.17
Details
Insect Cells Human rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.5 mg Log in to see 59 to 64 Days
$8,623.45
Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 39 to 44 Days
$9,248.02
Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 39 to 44 Days
$9,248.02
Details
HOST_HEK-293 Human His tag 50 μg Log in to see 2 to 3 Days
$630.00
Details
HOST_Escherichia coli (E. coli) Human GST tag 50 μg Log in to see 21 to 26 Days
$341.00
Details

TFRC Proteins by Origin and Source

Origin Expressed in Conjugate
Mouse (Murine) , ,
,
Rat (Rattus)

Human , , , , , , ,
, , , ,

Top referenced Transferrin Receptor (p90, CD71) Proteins

  1. Human TFRC Protein expressed in Human Cells - ABIN2003733 : Tosoni, Puri, Confalonieri, Salcini, De Camilli, Tacchetti, Di Fiore: TTP specifically regulates the internalization of the transferrin receptor. in Cell 2005 (PubMed)
    Show all 4 references for ABIN2003733

  2. Mouse (Murine) TFRC Protein expressed in Human Cells - ABIN2008269 : Douabin-Gicquel, Soriano, Ferran, Wojcik, Palierne, Tamim, Jovelin, McKie, Le Gall, David, Mosser: Identification of 96 single nucleotide polymorphisms in eight genes involved in iron metabolism: efficiency of bioinformatic extraction compared with a systematic sequencing approach. in Human genetics 2001 (PubMed)
    Show all 4 references for ABIN2008269

  3. Cynomolgus TFRC Protein expressed in Human Cells - ABIN2010052 : Wollscheid, Bausch-Fluck, Henderson, OBrien, Bibel, Schiess, Aebersold, Watts: Mass-spectrometric identification and relative quantification of N-linked cell surface glycoproteins. in Nature biotechnology 2009 (PubMed)
    Show all 3 references for ABIN2010052

  4. Human TFRC Protein expressed in Escherichia coli (E. coli) - ABIN1047756 : Schneider, Owen, Banville, Williams: Primary structure of human transferrin receptor deduced from the mRNA sequence. in Nature 1984 (PubMed)
    Show all 3 references for ABIN1047756

More Proteins for Transferrin Receptor (p90, CD71) (TFRC) Interaction Partners

Mouse (Murine) Transferrin Receptor (p90, CD71) (TFRC) interaction partners

  1. Mice lacking Tfr1 in the heart died in the second week of life and had cardiomegaly, poor cardiac function, failure of mitochondrial respiration, and ineffective mitophagy.

  2. Transferrin Receptor 1 (show TFR Proteins) Facilitates Poliovirus Permeation of Mouse Brain Capillary Endothelial Cells.

  3. Erythrocytic iron deficiency enhances susceptibility to Plasmodium chabaudi infection in mice carrying a missense mutation in tfr1.

  4. Tfr1 has a role in homeostatic maintenance of the intestinal epithelium, acting through a role that is independent of its iron-uptake function

  5. Analysis by qPCR showed changes in mRNA levels of iron-responsive genes, indicating moderately increased iron in the RPE (show RPE Proteins) of 10-month HID mice.

  6. characterization of erythropoiesis, iron status, and hepcidin (show HAMP Proteins) expression in mice with global or hematopoietic cell-specific haploinsufficiency of transferrin receptor 1 (show TFR Proteins) provides initial supporting data for this model

  7. high levels of TfRs such as those found on activated lymphocytes were found to be associated with decreased KLRG1 (show KLRG1 Proteins) inhibitory function, indicating that TfRs may sequester KLRG1 (show KLRG1 Proteins) from interacting with cadherins.

  8. data further demonstrate that the inhibitory activity of KLRG1 (show KLRG1 Proteins) is decreased in T cells expressing high levels of TfR, indicating that association of KLRG1 (show KLRG1 Proteins) with TfR hinders KLRG1 (show KLRG1 Proteins)-mediated silencing.

  9. high-affinity anti-TfR alters TfR trafficking, which dramatically impacts the capacity for TfR to mediate blood-brain barrier transcytosis

  10. Data indicate increased levels of reactive oxygen species (ROS (show ROS1 Proteins)) were detected in bone marrow nucleated cells (BMNC) that express CD71 in in NUP98 (show NUP98 Proteins)-HOXD13 (show HOXD13 Proteins) (NHD13) transgenic mice, a murine model for myelodysplastic syndromes (MDS (show MECOM Proteins)).

Human Transferrin Receptor (p90, CD71) (TFRC) interaction partners

  1. Together, our findings reveal that TfR1 can contribute to the mitochondrial respiration and ROS (show ROS1 Proteins) production, which have essential roles in growth and survival of pancreatic cancer.

  2. siRNA targeted delivery using transferrin (show Tf Proteins)-coupled lipoplexes specifically sensitizes CD71 high expressing malignant cells to antibody-mediated complement attack

  3. The requirement for a threshold level of TFR1 expression can explain why among primary human hematopoietic cells, only erythroblasts efficiently take up H-ferritin.

  4. Data indicate only the glycoproteins CD34 (show CD34 Proteins)+/CD71low population showed statistically significant differences between Diamond-Blackfan Anaemia (DBA (show RPS19 Proteins)) patients and controls.

  5. These results demonstrate that in cells expressing the hTfR, Tacaribe virus internalization depends on the presence of cholesterol, dynamin (show DNM1 Proteins) and acidic intracellular vesicles.

  6. The importance of TfR1 in adaptive immunity.A missense mutation in TFRC, encoding transferrin receptor 1 (show TFR Proteins), causes combined immunodeficiency.

  7. The blood levels of TfRC was higher in age-related macular degeneration patients than controls.No association was found between age-related macular degeneration occurrence and the p.Gly142Ser polymorphism of the TRFC gene.

  8. Data show that interleukin 6 (IL-6 (show IL6 Proteins)) secretion and the percentage of CD71 antigen-positive T lymphocytes both uniquely predicted survival independent of papillomavirus infection status.

  9. Data show that transferrin (show Tf Proteins) (Tf) was attached to nanoparticles with an acid-cleavable linkage that facilities release of nanoparticles from Tf that are bound to Tf receptors (TfR) during transcytosis, promoting entry of the nanoparticles into the brain.

  10. This study provides insights into the effector functions of human IgG3 in the context of an antibody targeting TfR1.

Horse (Equine) Transferrin Receptor (p90, CD71) (TFRC) interaction partners

  1. These data indicate that TfR1 expression in serum exosomes may provide a marker for regeneration in anaemic horses.

Pig (Porcine) Transferrin Receptor (p90, CD71) (TFRC) interaction partners

Transferrin Receptor (p90, CD71) (TFRC) Protein Profile

Protein Summary

This gene encodes a cell surface receptor necessary for cellular iron uptake by the process of receptor-mediated endocytosis. This receptor is required for erythropoiesis and neurologic development. Mice that are deficient in this receptor show impaired erythroid development and abnormal iron homeostasis.

Gene names and symbols associated with TFRC

  • transferrin receptor (p90, CD71) (TFRC)
  • transferrin receptor (p90, CD71) (tfrc)
  • transferrin receptor (p90, CD71) (LOC100219280)
  • transferrin receptor (Tfrc)
  • 2610028K12Rik protein
  • AI195355 protein
  • AI426448 protein
  • AU015758 protein
  • CD71 protein
  • E430033M20Rik protein
  • LOC100219280 protein
  • Mtvr-1 protein
  • Mtvr1 protein
  • p90 protein
  • T9 protein
  • TFR protein
  • TFR1 protein
  • TFRC protein
  • TR protein
  • TRFR protein

Protein level used designations for TFRC

transferrin receptor protein 1 , transferrin receptor (p90, CD71) , mammary tumor virus receptor 1 , TR , tfR , tfR1 , trfr

GENE ID SPECIES
504698 Bos taurus
698146 Macaca mulatta
100038175 Xenopus (Silurana) tropicalis
100219280 Taeniopygia guttata
22042 Mus musculus
64678 Rattus norvegicus
7037 Homo sapiens
493880 Felis catus
396191 Gallus gallus
403703 Canis lupus familiaris
100034089 Equus caballus
397062 Sus scrofa
100171944 Pongo abelii
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