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Transformer 2 beta Homolog (Drosophila) Proteins (TRA2B)

TRA2B encodes a nuclear protein which functions as sequence-specific serine/arginine splicing factor which plays a role in mRNA processing, splicing patterns, and gene expression. Additionally we are shipping TRA2B Antibodies (41) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
TRA2B 6434 P62995
TRA2B 20462 P62996
Rat TRA2B TRA2B 117259 P62997
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Top TRA2B Proteins at antibodies-online.com

Showing 7 out of 8 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Wheat germ Human GST tag 10 μg Log in to see 9 Days
$405.71
Details
Yeast Cow His tag   1 mg Log in to see 56 to 66 Days
$2,755.50
Details
HOST_Escherichia coli (E. coli) Human His tag   100 μg Log in to see 11 to 13 Days
$880.00
Details
HOST_Escherichia coli (E. coli) Human Un-conjugated   100 μg Log in to see 9 to 19 Days
$1,046.42
Details
HOST_Human Human Un-conjugated   20 μg Log in to see 9 to 11 Days
$785.40
Details

TRA2B Proteins by Origin and Source

Origin Expressed in Conjugate
Human , ,
,
Mouse (Murine)

More Proteins for Transformer 2 beta Homolog (Drosophila) (TRA2B) Interaction Partners

Human Transformer 2 beta Homolog (Drosophila) (TRA2B) interaction partners

  1. that TRA2beta promotes glioma cell growth and migration, and could be a candidate for molecular targeting during gene therapy treatments of glioma

  2. Tra2beta was significantly upregulated in prostate carcinoma, and multivariate analysis confirmed Tra2beta as an independent prognostic factor.

  3. Overexpression of either Tra2alpha (show TRA2A Proteins) or Tra2beta results in a marked reduction in HIV-1 Gag/ Env (show ERVW-1 Proteins) expression.

  4. Results showed that HNRNPG (show RBMX Proteins) and HTRA2 (show HTRA2 Proteins)-BETA1 were specific antagonistic regulators of ERa exon7 splicing and increased HNRNPG (show RBMX Proteins) levels were associated with improved clinical outcome of endometrial cancer through up-regulation of ERaD7 expression.

  5. findings suggest that Tra2beta regulates apoptosis by modulating Bcl-2 (show BCL2 Proteins) expression through its competition with miR (show MLXIP Proteins)-204. This novel function may have a crucial role in tumor growth.

  6. SRPK1 (show SRPK1 Proteins) is a regulator of Tra2beta1 splicing function and individual domains engage in considerable cross-talk, assuming novel functions with regard to RNA binding, splicing, and catalysis.

  7. Simultaneous depletion of Tra2alpha (show TRA2A Proteins) and Tra2beta induces substantial shifts in splicing of endogenous Tra2beta target exons, and both constitutive and alternative target exons are under dual Tra2alpha (show TRA2A Proteins)-Tra2beta control.

  8. Results indicate that transformer 2beta (Tra2beta) was involved in the tumorigenesis of NSCLC and might be a potential therapeutic target of non-small cell lung cancer (NSCLC).

  9. Facilitating Tra2beta-dependent inclusion of exons in target pre-mRNAs.

  10. SFRS10 is not expressed in normal human retinae but is upregulated in Age-related macular degeneration retinae.

Mouse (Murine) Transformer 2 beta Homolog (Drosophila) (TRA2B) interaction partners

  1. results indicate that high expression level of Tra2-beta1 is responsible for increased SMN2 (show SMN1 Proteins) exon 7 inclusion in the testis of SMA (show SMN1 Proteins) mice.

  2. Maturation of mesenteric artery smooth muscle involves TRA2beta mediated Mypt1 (show PPP1R12A Proteins) exon 24 splicing.

  3. TRA2B has a role in regulating protein kinase C deltaI splice variant expression during 3T3L1 preadipocyte cell cycle

  4. Tra2b regulates splicing events essential for maintaining neuronal viability during development.

  5. TRA2B is essential for proper development of the cerebral cortex.

  6. Sfrs10 (show SRSF2 Proteins) expression is observed in rod photoreceptors in a peri (show POSTN Proteins)-nuclear pattern.

  7. Tra2beta, by regulating the splicing of Mypt1 (show PPP1R12A Proteins) E23, sets the sensitivity of smooth muscle to cGMP-mediated relaxation.

  8. Normal activation of these regulated exons depends on multiple Tra2b binding sites, and significant mis (show AMH Proteins)-regulation of these exons is observed during mouse development when Tra2b is removed.

TRA2B Protein Profile

Protein Summary

This gene encodes a nuclear protein which functions as sequence-specific serine/arginine splicing factor which plays a role in mRNA processing, splicing patterns, and gene expression. Alternative splicing results in multiple transcript variants.

Gene names and symbols associated with TRA2B

  • transformer 2 beta homolog (Drosophila) (tra2b)
  • transformer 2 beta homolog (tra2b)
  • transformer 2 beta homolog (Drosophila) (TRA2B)
  • transformer 2 beta homolog (Drosophila) (Tra2b)
  • 5730405G21Rik protein
  • D16Ertd266e protein
  • Htra2-beta protein
  • Sfrs10 protein
  • SIG-41 protein
  • Silg41 protein
  • SRFS10 protein
  • Srsf10 protein
  • TRA2-BETA protein
  • TRA2beta protein
  • TRAN2B protein
  • zgc:56612 protein

Protein level used designations for TRA2B

transformer-2 protein homolog beta , Splicing factor, arginine/serine-rich 10 , splicing factor, arginine/serine-rich 10 , splicing factor, arginine/serine-rich 10 (transformer 2 homolog, Drosophila) , transformer-2 beta , TRA-2 beta , transformer-2 protein homolog B , TRA2-beta , silica-induced gene 41 protein , RA301 , serine/arginine-rich splicing factor 10 , splicing factor, arginine/serine-rich, 10

GENE ID SPECIES
100195215 Salmo salar
398448 Xenopus laevis
395403 Gallus gallus
6434 Homo sapiens
478663 Canis lupus familiaris
768108 Sus scrofa
615156 Bos taurus
20462 Mus musculus
117259 Rattus norvegicus
394172 Danio rerio
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