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anti-Transforming Growth Factor, beta Receptor 1 (TGFBR1) Antibodies

The protein encoded by TGFBR1 forms a heteromeric complex with type II TGF-beta receptors when bound to TGF-beta, transducing the TGF-beta signal from the cell surface to the cytoplasm. Additionally we are shipping TGFBR1 Kits (18) and TGFBR1 Proteins (15) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
TGFBR1 7046 P36897
TGFBR1 29591  
TGFBR1 21812 Q64729
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Top anti-TGFBR1 Antibodies at antibodies-online.com

Showing 10 out of 127 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Rabbit Un-conjugated IF (p), IHC (p), WB 100 μL Log in to see 3 to 7 Days
$269.50
Details
Human Rabbit Un-conjugated IHC (p), WB Western blot analysis of anti-TGFBR1 Pab (ABIN392279) in Jurkat cell line lysates (35 µg/lane). TGFBR1 (arrow) was detected using the purified polyclonal antibody. The anti-TGFBR1 Pab (ABIN392279) is used in Western blot to detect TGFBR1 in mouse small intestine tissue lysate. 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Rabbit Un-conjugated EIA, IHC (p), WB 0.4 mL Log in to see 6 to 8 Days
$390.50
Details
Human Rabbit Un-conjugated IF, ELISA, WB Western blot analysis of extracts from HepG2/COLO cells, using TGF beta Receptor I (Ab-165) Antibody. The lane on the right is treated with the synthesized peptide. Immunofluorescence analysis of HeLa cells, using TGF beta Receptor I (Ab-165) Antibody. The picture on the right is treated with the synthesized peptide. 100 μg Log in to see 2 to 3 Days
$302.50
Details
Human Rabbit Un-conjugated IF, WB 0.1 mg Log in to see 6 to 8 Days
$390.50
Details
Human Rabbit Un-conjugated IF, ELISA   100 μg Log in to see 2 to 3 Days
$302.50
Details
Human Rabbit Un-conjugated WB 100 μg Log in to see 4 to 6 Days
$240.00
Details
Human Rabbit Un-conjugated ICC, FACS, IF, IHC (p), WB WB Image TGF beta Receptor I antibody detects TGFBR1 protein by Western blot analysis. A. 30 µg PC-12 whole cell lysate/extract 7.5 % SDS-PAGE TGF beta Receptor I antibody , dilution: 1:10000 WB Image TGF beta Receptor I antibody detects TGF beta Receptor I protein by western blot analysis. Various whole cell extracts (30 μg) were separated by 10% SDS-PAGE, and the membrane was blotted with TGF beta Receptor I antibody , diluted by 1:1000. 100 μL Log in to see 2 to 3 Days
$358.60
Details
Mouse Goat Un-conjugated ELISA, WB 0.1 mg Log in to see 2 to 3 Days
$433.13
Details
Human Rabbit Un-conjugated IHC (p), WB 50 μg Log in to see 6 to 8 Days
$500.50
Details

TGFBR1 Antibodies by Reactivity, Application, Clonality and Conjugate

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Top referenced anti-TGFBR1 Antibodies

  1. Human Polyclonal TGFBR1 Primary Antibody for EIA, IHC (p) - ABIN360163 : Itoh, Thorikay, Kowanetz, Moustakas, Itoh, Heldin, ten Dijke: Elucidation of Smad requirement in transforming growth factor-beta type I receptor-induced responses. in The Journal of biological chemistry 2003 (PubMed)
    Show all 3 references for ABIN360163

  2. Human Polyclonal TGFBR1 Primary Antibody for IF, ELISA - ABIN1532728 : Franzén, ten Dijke, Ichijo, Yamashita, Schulz, Heldin, Miyazono: Cloning of a TGF beta type I receptor that forms a heteromeric complex with the TGF beta type II receptor. in Cell 1993 (PubMed)
    Show all 2 references for ABIN1532728

  3. Human Polyclonal TGFBR1 Primary Antibody for IHC (p), WB - ABIN392279 : Miles, Tung, Aguiar, Kurtoglu, Sikes: Increased TGF-?1-mediated suppression of growth and motility in castrate-resistant prostate cancer cells is consistent with Smad2/3 signaling. in The Prostate 2012 (PubMed)
    Show all 2 references for ABIN392279

  4. Human Polyclonal TGFBR1 Primary Antibody for IF, ELISA - ABIN1450347 : Vellucci, Reiss: Cloning and genomic organization of the human transforming growth factor-beta type I receptor gene. in Genomics 1998 (PubMed)
    Show all 2 references for ABIN1450347

  5. Human Polyclonal TGFBR1 Primary Antibody for IF, WB - ABIN317892 : Yu, Hu, Yang, Takemori, Li, Zheng, Hong, Liao, Wen: Salt-inducible kinase 1 is involved in high glucose-induced mesangial cell proliferation mediated by the ALK5 signaling pathway. in International journal of molecular medicine 2013 (PubMed)

More Antibodies against TGFBR1 Interaction Partners

Human Transforming Growth Factor, beta Receptor 1 (TGFBR1) interaction partners

  1. Evidence supporting a genetic basis includes the autosomal dominance of Bicuspid aortic valve inheritance patterns, and the identification of mutations in transforming growth factor beta receptor 1.

  2. This work details a novel mechanism by which cellular tension regulates TGFbeta (show TGFB1 Antibodies) receptor organization, multimerization, and function.

  3. miR (show MLXIP Antibodies)-181b functions as a tumor suppressor and has an important role in proliferation, chemosensitivity to DDP (show TIMM8A Antibodies) and metastasis of NSCLC by targeting TGFbetaR1/Smad (show SMAD1 Antibodies) signaling pathway.

  4. This paper highlights that targeting the BMP and TGFbeta (show TGFB1 Antibodies) type I and type II receptors causes a downregulation of XIAP (show XIAP Antibodies), TAK1 (show MAP3K7 Antibodies), and Id1 (show ID1 Antibodies) leading to cell death of lung cancer cells.

  5. Protease activated receptor-1 (show F2R Antibodies) mediated dual kinase receptor transactivation stimulates the expression of glycosaminoglycan synthesizing genes and transforming growth factor beta receptor 1

  6. Studies indicate that the transforming growth factor beta receptor I 6A (TbetaR-I 6A) allele was associated with breast cancer risk.

  7. Women who carry the TGFBR1*6A allele are at lower risk of developing breast cancer.

  8. the level of TGFBR1 and early osteogenic differentiation were abolished in the DPSCs transfected with siRNA for GnT-V knockdown...GnT-V plays a critical role in the hexosamine-induced activation of TGF-b signaling and osteogenic differentiation

  9. Data suggest that transient suppression of TGFbeta (show TGFB1 Antibodies) receptor I (TGFbeta (show TGFB1 Antibodies) receptor) signaling may improve the outcome of islet transplantation.

  10. Blocking TGFBR1 receptor up-regulated p21 (show CDKN1A Antibodies) expression while inhibiting breast tumor cell growth.

Pig (Porcine) Transforming Growth Factor, beta Receptor 1 (TGFBR1) interaction partners

  1. The results indicate that the TGFBR1 gene polymorphism (SNP64) is significantly associated with growth rates including average daily gains between birth and 56 kg, between 5.5 and 56 kg, between 35 and 56 kg.

  2. Report temporal regulation of TGFBR1 mRNA expression in the oocyte, granulosa and theca cells of developing preovulatory follicles in the pig.

  3. TGFbeta (show TGFB1 Antibodies) is abundant in boar seminal plasma, thus TGFbeta (show TGFB1 Antibodies) may be a male-female signalling agent involved in immune changes in the female reproductive tract elicited by seminal fluid.

  4. Porcine transforming growth factor beta receptor 1 has many polymorphisms, including two nonsynonymous substitutions in exons 1 and 7 and novel alternative splicing in exon 3.

  5. isolation and molecular characterization; the full-length TGFBR1 cDNA 1813 bp contains an open reading frame (ORF) of 1512 bp encoding a TGFBR1 protein of 503 amino acids with a calculated molecular weight of 56.4 kDa.

Cow (Bovine) Transforming Growth Factor, beta Receptor 1 (TGFBR1) interaction partners

  1. Results show that ALK5 and ALK1 (show ACVRL1 Antibodies) play antagonistic roles in TGF-beta (show TGFB1 Antibodies)-induced podosome formation in aortic endothelial cells.

  2. This study showed that ubiquitinated ALK5 and phosphorylated heat shock protein 27 specifically accumulate in the cytoskeleton fraction, and ALK1 (show ACVRL1 Antibodies) and ALK5 interact with heat shock protein 90 (show HSP90 Antibodies).

  3. GM-CSF (show CSF2 Antibodies) induced airway smooth muscle cells to increase expression of transforming growth factor (TGF)-beta (show TGFB1 Antibodies) receptors type I, II, and III, but had no detectable effect on the release of TGF-beta1 (show TGFB1 Antibodies) by the same ASMC; corticosteroids were inhibitory

  4. ALK5 and Smad4 (show SMAD4 Antibodies) have roles in TGF-beta1 (show TGFB1 Antibodies)-induced pulmonary endothelial permeability

  5. These results indicate that high plasma cholesterol levels may contribute to the pathogenesis of certain diseases (e.g., atherosclerosis) by suppressing TGF-beta (show TGFB1 Antibodies) responsiveness.

  6. Transforming growth factor-beta1 protects against pulmonary artery endothelial cell apoptosis via ALK5.

  7. ALK1 and ALK5 are both essential for correct regulation of VEGF, and that disruption of either pathway leads to disease.

  8. TGF-beta1 (show TGFB1 Antibodies) downregulates caveolin-1 (show CAV1 Antibodies) of cultured endothelial cells, involving ALK-5 receptor subtype

Mouse (Murine) Transforming Growth Factor, beta Receptor 1 (TGFBR1) interaction partners

  1. Targeted early inactivation of Alk5 in mesodermal progenitors caused abnormal development and maturation of the lung that included reduced physical size of the sub-mesothelial mesoderm, an established source of specific mesodermal progenitors.

  2. Beclin 1 (show BECN1 Antibodies) regulates neuronal transforming growth factor-beta signaling by mediating recycling of the type I receptor ALK5

  3. TGFbeta (show TGFB1 Antibodies)-ALK5 signaling has an antifibrotic effect in experimental pulmonary fibrosis in mice, which is attenuated in the presence of concurrent gamma-herpesvirus infection

  4. In vascular sprouting, neuropilin-1 (show NRP1 Antibodies) suppresses the stalk-cell phenotype by limiting Smad2 (show SMAD2 Antibodies)/3 activation through Alk1 (show ACVRL1 Antibodies) and Alk5. Notch (show NOTCH1 Antibodies) downregulates Nrp1 (show NRP1 Antibodies), thus relieving the inhibition of Alk1 (show ACVRL1 Antibodies) and Alk5, thereby driving stalk-cell behaviour.

  5. Endocytic deficiency caused by ITSN (show ITSN1 Antibodies) knock-down modified Alk5 endocytic trafficking and enhances its degradation

  6. Data indicate that absence of uterine activin receptor-like kinase 5 (ALK5) resulted in reduced female reproduction due to abnormalities observed at different stages of pregnancy.

  7. Litomosoides sigmodontis induces TGF-beta (show TGFB1 Antibodies) receptor responsive, IL-10 (show IL10 Antibodies)-producing T cells that suppress bystander T-cell proliferation in mice.

  8. constitutive activation of TGFBR1 in the mouse uterus caused defects in uterine morphology and function, as evidenced by abnormal myometrial structure, dramatically reduced uterine glands, and impaired uterine decidualization.

  9. Inhibition of ALK5 improved intraislet endothelial cell numbers after islet culture, but this effect was lost in the early post-transplantation period.

  10. SD-208, a TbetaRI kinase inhibitor, stimulated tumour growth of invasive lobular carcinoma and bone metastases.

TGFBR1 Antigen Profile

Protein Summary

The protein encoded by this gene forms a heteromeric complex with type II TGF-beta receptors when bound to TGF-beta, transducing the TGF-beta signal from the cell surface to the cytoplasm. The encoded protein is a serine/threonine protein kinase. Mutations in this gene have been associated with Loeys-Dietz aortic aneurysm syndrome (LDAS). Multiple transcript variants encoding different isoforms have been found for this gene.

Gene names and symbols associated with TGFBR1

  • transforming growth factor, beta receptor I (activin A receptor type II-like kinase, 53kDa) (TGFBR1) antibody
  • transforming growth factor, beta receptor 1 (tgfbr1) antibody
  • transforming growth factor, beta receptor 1 (TGFBR1) antibody
  • transforming growth factor, beta receptor I (activin A receptor type II-like kinase, 53kDa) (LOC100230911) antibody
  • transforming growth factor, beta receptor 1 (Tgfbr1) antibody
  • transforming growth factor, beta receptor I (Tgfbr1) antibody
  • AAT5 antibody
  • ACVRLK4 antibody
  • Alk-5 antibody
  • Alk5 antibody
  • AU017191 antibody
  • LDS1A antibody
  • LDS2A antibody
  • MSSE antibody
  • Skr4 antibody
  • TbetaR-I antibody
  • TbetaRI antibody
  • TGFBR1 antibody
  • Tgfr-1 antibody
  • x-trr1 antibody

Protein level used designations for TGFBR1

TGF-beta receptor type-1 , type I serine/threonine kinase receptor , transforming growth factor, beta receptor I (activin A receptor type II-like kinase, 53kDa) , transforming growth factor beta type I receptor , transforming growth factor, beta receptor 1 (activin A receptor type II-like kinase, 53kDa) , transforming growth factor, beta receptor 1 , transforming growth factor beta receptor 1 , TGF-beta receptor type-1-like , TGF-beta receptor type I , TGF-beta type I receptor , activin A receptor type II-like kinase, 53kD , activin A receptor type II-like kinase, 53kDa , activin A receptor type II-like protein kinase of 53kD , activin receptor-like kinase 5 , serine/threonine-protein kinase receptor R4 , tbetaR-I , transforming growth factor beta receptor I , transforming growth factor, beta receptor I (activin A receptor type II-like kinase, 53kD) , transforming growth factor-beta receptor type I , transforming growth factor, beta receptor I , TGFR-1 , activin A receptor type II-like kinase , transforming growth factor beta receptor type I , transforming growth factor beta, receptor 1 , ESK2

GENE ID SPECIES
374094 Gallus gallus
399295 Xenopus laevis
403428 Canis lupus familiaris
472992 Pan troglodytes
481628 Canis lupus familiaris
548715 Xenopus (Silurana) tropicalis
554326 Ovis aries
714952 Macaca mulatta
100230911 Taeniopygia guttata
100389596 Callithrix jacchus
100450864 Pongo abelii
100592854 Nomascus leucogenys
7046 Homo sapiens
29591 Rattus norvegicus
396665 Sus scrofa
282382 Bos taurus
21812 Mus musculus
Selected quality suppliers for anti-TGFBR1 (TGFBR1) Antibodies
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