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anti-Transforming Growth Factor, beta Receptor II (70/80kDa) (TGFBR2) Antibodies

TGFBR2 encodes a member of the Ser/Thr protein kinase family and the TGFB receptor subfamily. Additionally we are shipping TGFBR2 Proteins (26) and TGFBR2 Kits (17) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
TGFBR2 21813 Q62312
TGFBR2 81810 P38438
TGFBR2 7048 P37173
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Top anti-TGFBR2 Antibodies at antibodies-online.com

Showing 10 out of 113 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Cow Rabbit Un-conjugated WB WB Suggested Anti-TGFBR2 Antibody Titration: 5.0ug/mlPositive Control: HepG2 cell lysate 100 μL Log in to see 2 to 3 Days
$229.00
Details
Human Rabbit Un-conjugated EIA, IF, IHC (p), WB Confocal immunofluorescent analysis of TGFBR2 Antibody (N-term) with HepG2 cell followed by Alexa Fluor 488-conjugated goat anti-rabbit lgG (green). DAPI was used to stain the cell nuclear (blue). TGFBR2 Antibody (N-term) immunohistochemistry analysis in formalin fixed and paraffin embedded human placenta tissue followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of TGFBR2 Antibody (N-term) for immunohistochemistry. Clinical relevance has not been evaluated. 0.4 mL Log in to see 6 to 8 Days
$401.50
Details
Mouse Rabbit Un-conjugated IF, IHC (p), WB Confocal immunofluorescent analysis of TGFBR2 Antibody (N-term) (ABIN655799) with HepG2 cell followed by Alexa Fluor 488-conjugated goat anti-rabbit lgG (green). DAPI was used to stain the cell nuclear (blue). 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Rabbit Un-conjugated IHC, ELISA, WB The TGF-beta Receptor Type II Antibody is used in Western blot to detect TGF-beta receptor type II in rat brain lysates. TGF-beta Receptor Type II staining in rat colon. Paraffin-embedded rat colon is stained with TGF-beta Receptor Type II Antibody used at 1:200 dilution. 0.1 mg Log in to see 2 to 6 Days
$359.70
Details
Human Rabbit Un-conjugated IHC (p), WB 0.1 mg Log in to see 6 to 8 Days
$390.50
Details
Human Rabbit Un-conjugated WB 100 μg Log in to see 4 to 6 Days
$240.00
Details
Human Rabbit Un-conjugated WB Lane 2: COLO320 Whole Cell Lysate at 40ug Predicted bind size: 65KD Observed bind size: 65KD 100 μg Log in to see 4 to 6 Days
$200.00
Details
Human Mouse Un-conjugated ELISA, WB TGFBR2 polyclonal antibody (A01), Lot # 060525JCSI. Western Blot analysis of TGFBR2 expression in Raw 264.7. Western Blot detection against Immunogen (37.55 KDa) . 50 μL Log in to see 9 Days
$298.57
Details
Rat Rabbit Un-conjugated IHC (p), WB Anti-TGFBR2 antibody IHC staining of human lung, vascular endothelium. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody  ABIN1104648 dilution 5 ug/ml. 50 μg Log in to see 8 to 10 Days
$451.00
Details
Human Rabbit Un-conjugated ELISA, WB 100 μL Log in to see 8 to 10 Days
$478.50
Details

TGFBR2 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
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Rat (Rattus)


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Top referenced anti-TGFBR2 Antibodies

  1. Human Polyclonal TGFBR2 Primary Antibody for EIA, IF - ABIN955177 : Inamoto, Kwartler, Lafont, Liang, Fadulu, Duraisamy, Willing, Estrera, Safi, Hannibal, Carey, Wiktorowicz, Tan, Feng, Pannu, Milewicz: TGFBR2 mutations alter smooth muscle cell phenotype and predispose to thoracic aortic aneurysms and dissections. in Cardiovascular research 2010 (PubMed)
    Show all 4 references for ABIN955177

  2. Cow (Bovine) Polyclonal TGFBR2 Primary Antibody for WB - ABIN2781999 : Song, Krebs, Danielpour: Novel permissive role of epidermal growth factor in transforming growth factor beta (TGF-beta) signaling and growth suppression. Mediation by stabilization of TGF-beta receptor type II. in The Journal of biological chemistry 2006 (PubMed)

  3. Human Polyclonal TGFBR2 Primary Antibody for ELISA, WB - ABIN520882 : Cook, Choudhuri, Degraff, Gamson, Mitchell: Halofuginone enhances the radiation sensitivity of human tumor cell lines. in Cancer letters 2010 (PubMed)

  4. Human Polyclonal TGFBR2 Primary Antibody for IHC, ELISA - ABIN1585382 : Li, Martijn, Cui, Essaghir, Luque, Demoulin, Castaño, Öberg, Giandomenico: The somatostatin analogue octreotide inhibits growth of small intestine neuroendocrine tumour cells. in PLoS ONE 2012 (PubMed)

  5. Mouse (Murine) Polyclonal TGFBR2 Primary Antibody for IF, IHC (p) - ABIN655799 : Liang, Li, Zhang, Cui, Quan, Yang: The anti-fibrotic effects of microRNA-153 by targeting TGFBR-2 in pulmonary fibrosis. in Experimental and molecular pathology 2015 (PubMed)

More Antibodies against TGFBR2 Interaction Partners

Rhesus Monkey Transforming Growth Factor, beta Receptor II (70/80kDa) (TGFBR2) interaction partners

  1. Expression of microRNA miR (show MYLIP Antibodies)-155 was significantly upregulated in the oropharyngeal mucosa during chronic SIV infection and was coincident with downregulation of TGFbeta (show TGFB1 Antibodies) receptor 2 (TGFbeta (show TGFB1 Antibodies)-R2) and SMAD5 (show SMAD5 Antibodies).

Mouse (Murine) Transforming Growth Factor, beta Receptor II (70/80kDa) (TGFBR2) interaction partners

  1. Epithelial TGFbeta (show TGFB1 Antibodies) signaling via TGFBR2 does not contribute to the development of liver fibrosis or formation of hepatocellular carcinomas in mice, but restricts cholangiocyte proliferation to prevent cholangiocarcinoma development.

  2. The removal of Tgfbr2 and treatment with losartan both delayed the progression of articular cartilage degeneration induced by medial meniscus (DMM (show COL2A1 Antibodies)) compared with control littermates.

  3. Data (including data from studies in transgenic mice) suggest intraislet pancreatic duct cells are capable of giving rise to insulin (show INS Antibodies)-secreting beta-cells; Tgfbr2/transforming growth factor-beta type II receptor appears to be involved in this process.

  4. Elimination of TGF-betaIIR is not sufficient to completely prevent liver fibrosis. TGF-beta (show TGFB1 Antibodies)-independent mechanism of type I collagen production and suggest connective tissue growth factor (show CTGF Antibodies) as its potent mediator.

  5. Overexpression of TGFbeta1 (show TGFB1 Antibodies) promotes pulmonary inflammation, apoptosis and mortality via TGFbetaR2 in the developing mouse lung.

  6. Loss of smooth muscle cells Tgfbr2 disrupts TGF-beta (show TGFB1 Antibodies) signaling, acutely alters SMC (show DYM Antibodies) gene expression, and rapidly results in severe and durable aortopathy.

  7. Increased Tgfbr2 expression is associated with pulmonary fibrosis.

  8. High TGFBR2 expression is associated with pancreatic carcinoma.

  9. Suggest that miR (show MLXIP Antibodies)-370 acting via TbetaRII might play a potential role in hepatic IR injury, and inhibition of miR (show MLXIP Antibodies)-370 efficiently attenuated the damage to the liver.

  10. skeletal phenotype of mice carrying a mutation in the TGF-beta (show TGFB1 Antibodies) type 2 receptor associated with severe Loeys-Dietz syndrome in humans: Cortical bone showed significantly reduced tissue area, bone area, and cortical thickness with increased eccentricity

Human Transforming Growth Factor, beta Receptor II (70/80kDa) (TGFBR2) interaction partners

  1. This work details a novel mechanism by which cellular tension regulates TGFbeta (show TGFB1 Antibodies) receptor organization, multimerization, and function.

  2. Findings suggest that the upregulation of miR (show MLXIP Antibodies)-590-5p promotes cellular malignant behavior via the target gene TGFbetaRII in vulvar squamous cell carcinoma.

  3. This paper highlights that targeting the BMP and TGFbeta (show TGFB1 Antibodies) type I and type II receptors causes a downregulation of XIAP (show XIAP Antibodies), TAK1 (show MAP3K7 Antibodies), and Id1 (show ID1 Antibodies) leading to cell death of lung cancer cells.

  4. TGF-beta2 (show TGFB2 Antibodies) induces Grb2 (show GRB2 Antibodies) to recruit PI3-K (show PIK3CA Antibodies) to TGF-RII that activates JNK (show MAPK8 Antibodies)/AP-1 (show FOSB Antibodies)-signaling and augments invasiveness of Theileria-transformed macrophages.

  5. TGFBR2 is regulated by an epigenetic auto-feedback regulation in non-small cell lung cancer.

  6. we reported a sporadic Japanese case of LDS with a novel TGFBR2 p.Y424H mutation, which appeared to cause pregnancy-related fatal aortic/arterial dissections.

  7. AT2R (show AGTR2 Antibodies) downregulates the expression of TGF-betaRII in human proximal tubule cells

  8. Case Report: endovascular repair of a left vertebral artery aneurysm in a patient with transforming growth factor beta receptor II mutation.

  9. Studied folding and crystallization of the type II TGF-beta (show TGFB1 Antibodies) receptor extracellular domain using the non-detergent sulfobetaine-201, which acts as a pharmacological chaperone.

  10. MiR (show MLXIP Antibodies)-1343 reduces the expression of both TGF-beta (show TGFB1 Antibodies) receptor 1 and 2 by directly targeting their 3'-UTRs.

Cow (Bovine) Transforming Growth Factor, beta Receptor II (70/80kDa) (TGFBR2) interaction partners

  1. These results indicate that high plasma cholesterol levels may contribute to the pathogenesis of certain diseases (e.g., atherosclerosis) by suppressing TGF-beta (show TGFB1 Antibodies) responsiveness.

TGFBR2 Antigen Profile

Protein Summary

This gene encodes a member of the Ser/Thr protein kinase family and the TGFB receptor subfamily. The encoded protein is a transmembrane protein that has a protein kinase domain, forms a heterodimeric complex with another receptor protein, and binds TGF-beta. This receptor/ligand complex phosphorylates proteins, which then enter the nucleus and regulate the transcription of a subset of genes related to cell proliferation. Mutations in this gene have been associated with Marfan Syndrome, Loeys-Deitz Aortic Aneurysm Syndrome, and the development of various types of tumors. Alternatively spliced transcript variants encoding different isoforms have been characterized.

Gene names and symbols associated with TGFBR2

  • transforming growth factor, beta receptor II (70/80kDa) (TGFBR2) antibody
  • transforming growth factor, beta receptor II (TGFBR2) antibody
  • transforming growth factor, beta receptor II (70/80kDa) (LOC100220619) antibody
  • transforming growth factor beta receptor II (LOC100038019) antibody
  • transforming growth factor, beta receptor II (Tgfbr2) antibody
  • transforming growth factor, beta receptor II-like (LOC424261) antibody
  • 1110020H15Rik antibody
  • AAT3 antibody
  • AU042018 antibody
  • DNIIR antibody
  • FAA3 antibody
  • LDS1B antibody
  • LDS2B antibody
  • MFS2 antibody
  • RIIC antibody
  • RIIDN antibody
  • TAAD2 antibody
  • TBETA-RII antibody
  • TbetaR-II antibody
  • TbetaRII antibody
  • TBR-II antibody
  • TGF-beta 2 antibody
  • TGFbeta-RII antibody
  • TGFBR2 antibody
  • Tgfbr2T antibody
  • TGFBRII antibody
  • TGFR-2 antibody

Protein level used designations for TGFBR2

transforming growth factor, beta receptor II (70/80kDa) , transforming growth factor beta type II receptor , transforming growth factor, beta receptor II , transforming growth factor beta receptor 2 , TGF-beta receptor type-2 , TGF beta receptor type II , TGF-beta receptor type-2-like , TGF-beta receptor II , TGF-beta receptor type II , TGF-beta type II receptor , TGFR-2 , transforming growth factor-beta receptor type II , tbetaR-II , transforming growth factor beta receptor type II , transforming growth factor beta, receptor 2 , transforming growth factor, beta receptor 2 , transforming growth factor, beta receptor IIT , transforming growth factor-b type II receptor , transforming growth factor-beta type II receptor , TGF-beta receptor type IIB , transforming growth factor beta receptor type IIC

GENE ID SPECIES
460243 Pan troglodytes
477039 Canis lupus familiaris
494191 Ovis aries
703088 Macaca mulatta
100031897 Monodelphis domestica
100033860 Equus caballus
100076965 Ornithorhynchus anatinus
100404359 Callithrix jacchus
100459236 Pongo abelii
100482939 Ailuropoda melanoleuca
100220619 Taeniopygia guttata
100606849 Nomascus leucogenys
100038019 Sus scrofa
21813 Mus musculus
81810 Rattus norvegicus
396399 Gallus gallus
7048 Homo sapiens
535376 Bos taurus
424261 Gallus gallus
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