Transforming Growth Factor, beta Receptor II (70/80kDa) (TGFBR2) ELISA Kits

TGFBR2 encodes a member of the Ser/Thr protein kinase family and the TGFB receptor subfamily. Additionally we are shipping TGFBR2 Antibodies (217) and TGFBR2 Proteins (31) and many more products for this protein.

list all ELISA KIts Gene Name GeneID UniProt
TGFBR2 21813 Q62312
TGFBR2 81810 P38438
TGFBR2 7048 P37173
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Top TGFBR2 ELISA Kits at antibodies-online.com

Showing 10 out of 42 products:

Catalog No. Reactivity Sensitivity Range Images Quantity Supplier Delivery Price Details
Human 0.115 ng/mL 0.31 ng/mL - 20 ng/mL 96 Tests Log in to see 13 to 16 Days
$589.47
Details
Mouse 0.112 ng/mL 0.31 ng/mL - 20 ng/mL 96 Tests Log in to see 13 to 16 Days
$606.32
Details
Mouse 0.105 ng/mL 0.312-20 ng/mL 96 Tests Log in to see 15 to 17 Days
$822.09
Details
Rat 0.129 ng/mL 0.31 ng/mL - 20 ng/mL 96 Tests Log in to see 13 to 16 Days
$640.00
Details
Human
  96 Tests Log in to see 2 to 3 Days
$380.00
Details
Mouse 0.128 ng/mL 0.312 ng/mL - 20 ng/mL   96 Tests Log in to see 8 to 12 Days
$787.25
Details
Human 0.115 ng/mL 0.312 ng/mL - 20 ng/mL   96 Tests Log in to see 8 to 12 Days
$766.25
Details
Rat 0.129 ng/mL 0.312 ng/mL - 20 ng/mL   96 Tests Log in to see 8 to 12 Days
$829.25
Details
Pig
  96 Tests Log in to see 15 to 18 Days
$1,029.60
Details
Chicken
  96 Tests Log in to see 15 to 18 Days
$1,095.60
Details

Top referenced TGFBR2 ELISA Kits

  1. Human TGFBR2 ELISA Kit for Sandwich ELISA - ABIN418671 : Zhang, Chen, Chen, Meng, Xiong, Liu, Jin, Tao, Wu, Sun: TGF-β/BAMBI pathway dysfunction contributes to peripheral Th17/Treg imbalance in chronic obstructive pulmonary disease. in Scientific reports 2016 (PubMed)

More ELISA Kits for TGFBR2 Interaction Partners

Rhesus Monkey Transforming Growth Factor, beta Receptor II (70/80kDa) (TGFBR2) interaction partners

  1. Expression of microRNA miR (show MYLIP ELISA Kits)-155 was significantly upregulated in the oropharyngeal mucosa during chronic SIV infection and was coincident with downregulation of TGFbeta (show TGFB1 ELISA Kits) receptor 2 (TGFbeta (show TGFB1 ELISA Kits)-R2) and SMAD5 (show SMAD5 ELISA Kits).

Mouse (Murine) Transforming Growth Factor, beta Receptor II (70/80kDa) (TGFBR2) interaction partners

  1. In young Fbn1 (show FBN1 ELISA Kits)(C1039G/+) mice, aortopathy develops in the absence of detectable alterations in smooth muscle cell (SMC (show DYM ELISA Kits)) TGF-beta (show TGFB1 ELISA Kits) signaling. Loss of physiologic SMC (show DYM ELISA Kits) TGF-beta (show TGFB1 ELISA Kits) signaling exacerbates MFS-associated aortopathy. Our data support a protective role for SMC (show DYM ELISA Kits) TGF-beta (show TGFB1 ELISA Kits) signaling during early development of MFS-associated aortopathy.

  2. The present study demonstrates that TGFbeta (show TGFB1 ELISA Kits) responsiveness in the myeloid compartment is critical in controlling autoimmune encephalomyelitis, and that its specific deletion in monocyte-derived dendritic cells causes severe experimental autoimmune encephalomyelitis without remission.

  3. These results suggest proliferation and maturation of immature osteoblasts requires Tgfbr2 signaling and that decreased bone volume in Osx (show SP7 ELISA Kits)-Cre;Tgfbr2(fl/fl (show FLT3LG ELISA Kits)) mice is likely due to fewer mature osteoblasts.

  4. The authors identify ELMO1 (show ELMO1 ELISA Kits) as a novel target of TGFbeta (show TGFB1 ELISA Kits) signaling and show that restoration of Tgfbr2 results in a complete block of ELMO1 (show ELMO1 ELISA Kits) in vivo. Knocking down Elmo1 (show ELMO1 ELISA Kits) impairs metastasis of carcinoma cells to the lung, thereby providing insights into the mechanisms of progression of Tgfbr2-deficient invasive transition zone squamous cell carcinoma.

  5. removing TGF-b type II receptor in DA neurons also disrupts the balance in TGF-b1 expression in DA neurons and neighboring GABAergic neurons, which increases inhibitory input, reduces excitatory synaptic input, and alters phasic firing patterns in DA neurons

  6. PAR1 (show F2R ELISA Kits) in its inactive unligated state functions as a scaffold for TGFbetaRII to downregulate TGF-beta (show TGFB1 ELISA Kits) signaling, and thereby promote embryonic stem cell transition to functional endothelial cells.

  7. Cell-intrinsic TGFbeta-RII signaling limits CD4 (show CD4 ELISA Kits) T cell proliferation but not prototypical T helper subset differentiation early after chronic lymphocytic choriomeningitis virus infection.

  8. These results suggest that DMSO, a fusogenic substance, enhances TGF-beta (show TGFB1 ELISA Kits) activity presumably by inducing fusion of cytoplasmic vesicles (containing TbetaR-II) and the plasma membrane, resulting in increased localization of TbetaR-II to non-lipid raft microdomains where canonical signaling occurs.

  9. USP11 (show USP11 ELISA Kits) may contribute to the pathogenesis of pulmonary fibrosis by stabilization of TbetaRII and promotion of TGFbeta (show TGFB1 ELISA Kits)-1 signaling.

  10. both GDF-15 (show GDF15 ELISA Kits) and TGF-beta1 (show TGFB1 ELISA Kits) counteract chemokine (show CCL1 ELISA Kits)-induced integrin activation on neutrophils via the ALK-5 (show TGFBR1 ELISA Kits)/TGF-betaRII heterodimer.

Human Transforming Growth Factor, beta Receptor II (70/80kDa) (TGFBR2) interaction partners

  1. MiR (show MLXIP ELISA Kits)-130 is up-regulated in gastric cancer (GC) tissues and directly targets TGF-beta type II receptor (TGFbetaR2).

  2. results suggest a role for prostatic expression of TGF-B, IL-1a (show IL1A ELISA Kits), TGFBRI and TGFBRII as prognostic markers for prostate cancer. The rational combination of novel agents directed toward the inactivation of TGF-B, IL-1a (show IL1A ELISA Kits), TGFBRI and TGFBRII could disrupt complementary tumor cell proliferation pathways.

  3. miR-17-5p negatively regulated TGFBR2 expression by directly binding to the 3'UTR (show UTS2R ELISA Kits) of TGFBR2 mRNA, thereby promoting gastric cancer cell growth and migration.

  4. High TGFBR2 expression is associated with mesenchymal to epithelial transition of breast cancer.

  5. Inhibition of TGFBR2 had the similar effect as miR (show MLXIP ELISA Kits)-9 overexpression.

  6. we describe and characterize the functional impact of a novel VUS in the TGFBR2 kinase domain (c.1255G>T; p.Val419Leu), in a patient with the clinical diagnosis of Marfan syndrome spectrum. Our results establish that the V419L variant leads to aberrant TGF-beta (show TGFB1 ELISA Kits) signaling and confirm the diagnosis of Loeys-Dietz syndrome in this patient.

  7. Apo (show C9orf3 ELISA Kits) and inhibitor-bound TGFBR2 kinase structures are presented at high resolution (<2 A).

  8. Aortic diseases in patients with TGFBR1 (show TGFBR1 ELISA Kits) or TGFBR2 mutations show the same prevalence of systemic features and the same global survival.

  9. TGF-beta (show TGFB1 ELISA Kits) type I, II, and III receptors were all identified in pregnant serum; all were substantially elevated in early-onset but not late-onset PE. Endoglin (show ENG ELISA Kits) was increased in both subtypes.

  10. Although TGFbeta1 (show TGFB1 ELISA Kits)/2 receptors are downregulated in breast cancer, their expression in tumors is an indicator of aggressive breast cancer phenotype.

Cow (Bovine) Transforming Growth Factor, beta Receptor II (70/80kDa) (TGFBR2) interaction partners

  1. These results indicate that high plasma cholesterol levels may contribute to the pathogenesis of certain diseases (e.g., atherosclerosis) by suppressing TGF-beta (show TGFB1 ELISA Kits) responsiveness.

TGFBR2 Antigen Profile

Antigen Summary

This gene encodes a member of the Ser/Thr protein kinase family and the TGFB receptor subfamily. The encoded protein is a transmembrane protein that has a protein kinase domain, forms a heterodimeric complex with another receptor protein, and binds TGF-beta. This receptor/ligand complex phosphorylates proteins, which then enter the nucleus and regulate the transcription of a subset of genes related to cell proliferation. Mutations in this gene have been associated with Marfan Syndrome, Loeys-Deitz Aortic Aneurysm Syndrome, and the development of various types of tumors. Alternatively spliced transcript variants encoding different isoforms have been characterized.

Gene names and symbols associated with TGFBR2

  • transforming growth factor beta receptor 2 (TGFBR2) antibody
  • transforming growth factor, beta receptor II (Tgfbr2) antibody
  • transforming growth factor, beta receptor 2 (Tgfbr2) antibody
  • anti-Mullerian hormone receptor, type II (AMHR2) antibody
  • 1110020H15Rik antibody
  • AAT3 antibody
  • AU042018 antibody
  • DNIIR antibody
  • FAA3 antibody
  • LDS1B antibody
  • LDS2B antibody
  • MFS2 antibody
  • RIIC antibody
  • RIIDN antibody
  • TAAD2 antibody
  • TBETA-RII antibody
  • TbetaR-II antibody
  • TbetaRII antibody
  • TBR-II antibody
  • TGF-beta 2 antibody
  • TGFbeta-RII antibody
  • TGFBR2 antibody
  • Tgfbr2T antibody
  • TGFBRII antibody
  • TGFR-2 antibody

Protein level used designations for TGFBR2

transforming growth factor, beta receptor II (70/80kDa) , transforming growth factor beta type II receptor , transforming growth factor, beta receptor II , transforming growth factor beta receptor 2 , TGF-beta receptor type-2 , TGF beta receptor type II , TGF-beta receptor type-2-like , TGF-beta receptor II , TGF-beta receptor type II , TGF-beta type II receptor , TGFR-2 , transforming growth factor-beta receptor type II , tbetaR-II , transforming growth factor beta receptor type II , transforming growth factor beta, receptor 2 , transforming growth factor, beta receptor 2 , transforming growth factor, beta receptor IIT , transforming growth factor-b type II receptor , transforming growth factor-beta type II receptor , TGF-beta receptor type IIB , transforming growth factor beta receptor type IIC

GENE ID SPECIES
460243 Pan troglodytes
477039 Canis lupus familiaris
494191 Ovis aries
703088 Macaca mulatta
100031897 Monodelphis domestica
100033860 Equus caballus
100076965 Ornithorhynchus anatinus
100404359 Callithrix jacchus
100459236 Pongo abelii
100482939 Ailuropoda melanoleuca
100220619 Taeniopygia guttata
100606849 Nomascus leucogenys
100038019 Sus scrofa
21813 Mus musculus
81810 Rattus norvegicus
396399 Gallus gallus
7048 Homo sapiens
535376 Bos taurus
424261 Gallus gallus
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