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anti-Transforming Growth Factor, beta Receptor II (70/80kDa) (TGFBR2) Antibodies

TGFBR2 encodes a member of the Ser/Thr protein kinase family and the TGFB receptor subfamily. Additionally we are shipping TGFBR2 Proteins (27) and TGFBR2 Kits (23) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
TGFBR2 21813 Q62312
TGFBR2 81810 P38438
TGFBR2 7048 P37173
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Top anti-TGFBR2 Antibodies at antibodies-online.com

Showing 10 out of 166 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Cow Rabbit Un-conjugated WB WB Suggested Anti-TGFBR2 Antibody Titration: 5.0ug/mlPositive Control: HepG2 cell lysate 100 μL Log in to see 2 to 3 Days
$229.00
Details
Mouse Rabbit Un-conjugated IF, IHC (p), WB Confocal immunofluorescent analysis of TGFBR2 Antibody (N-term) (ABIN655799) with HepG2 cell followed by Alexa Fluor 488-conjugated goat anti-rabbit lgG (green). DAPI was used to stain the cell nuclear (blue). 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Rabbit Un-conjugated EIA, IF, IHC (p), WB Confocal immunofluorescent analysis of TGFBR2 Antibody (N-term) with HepG2 cell followed by Alexa Fluor 488-conjugated goat anti-rabbit lgG (green). DAPI was used to stain the cell nuclear (blue). TGFBR2 Antibody (N-term) immunohistochemistry analysis in formalin fixed and paraffin embedded human placenta tissue followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of TGFBR2 Antibody (N-term) for immunohistochemistry. Clinical relevance has not been evaluated. 0.4 mL Log in to see 6 to 8 Days
$401.50
Details
Human Mouse Fluorescein FACS Detection of TGF-beta RII in NS0 Mouse Cell Line Transfected with TGF-beta RII by Flow Cytometry. NS0 mouse myeloma cell line transfected with TGF-beta RII was stained with Mouse Anti-Human TGF-beta RII Fluorescein-conjugated Monoclonal Antibody. 25 Tests Log in to see 6 to 7 Days
$164.06
Details
Human Mouse PE FACS Detection of TGF-beta RII in NS0 Mouse Cell Line transfected with TGF-beta RII by Flow Cytometry. NS0 mouse myeloma cell line transfected with TGF-beta RII was stained with Mouse Anti-Human TGF-beta RII PE-conjugated Monoclonal Antibody. 25 Tests Log in to see 6 to 7 Days
$200.81
Details
Human Rabbit Un-conjugated IHC (p), WB 0.1 mg Log in to see 6 to 8 Days
$390.50
Details
Mouse Goat Fluorescein FACS Detection of TGF-beta RII in Mouse Splenocytes by Flow Cytometry. Mouse splenocytes were stained with Goat Anti-Mouse TGF-beta RII Fluorescein-conjugated Antigen Affinity-purified Polyclonal Antibody. 25 Tests Log in to see 6 to 7 Days
$164.06
Details
Mouse Goat PE FACS Detection of TGF-beta RII in Mouse Splenocytes by Flow Cytometry. Mouse splenocytes were stained with Goat Anti-Mouse TGF-beta RII PE-conjugated Antigen Affinity-purified Polyclonal Antibody. 25 Tests Log in to see 6 to 7 Days
$200.81
Details
Human Goat PE FACS Detection of TGF-beta RII in Human Blood Lymphocytes by Flow Cytometry. Human peripheral blood lymphocytes were stained with Goat Anti-Human TGF-beta RII PE-conjugated Antigen Affinity-purified Polyclonal Antibody. 25 Tests Log in to see 6 to 7 Days
$200.81
Details
Mouse Goat Allophycocyanin FACS Detection of TGF-beta RII in Mouse Splenocytes by Flow Cytometry. Mouse splenocytes were stained with Goat Anti-Mouse TGF-beta RII APC-conjugated Antigen Affinity-purified Polyclonal Antibody. 25 Tests Log in to see 6 to 7 Days
$224.44
Details

TGFBR2 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
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Top referenced anti-TGFBR2 Antibodies

  1. Mouse (Murine) Polyclonal TGFBR2 Primary Antibody for FACS - ABIN4898045 : Lewis, Macal, Hesser, Zuñiga et al.: Constitutive but not inducible attenuation of transforming growth factor β signaling increases natural killer cell responses without directly affecting dendritic cells early after persistent viral ... in Journal of virology 2015 (PubMed)
    Show all 6 references for ABIN4898045

  2. Human Polyclonal TGFBR2 Primary Antibody for EIA, IF - ABIN955177 : Inamoto, Kwartler, Lafont, Liang, Fadulu, Duraisamy, Willing, Estrera, Safi, Hannibal, Carey, Wiktorowicz, Tan, Feng, Pannu, Milewicz: TGFBR2 mutations alter smooth muscle cell phenotype and predispose to thoracic aortic aneurysms and dissections. in Cardiovascular research 2010 (PubMed)
    Show all 4 references for ABIN955177

  3. Mouse (Murine) Polyclonal TGFBR2 Primary Antibody for FACS - ABIN4898037 : Gallo, Loch, Habashi, Calderon, Chen, Bedja, van Erp, Gerber, Parker, Sauls, Judge, Cooke, Lindsay, Rouf, Myers, ap Rhys, Kent, Norris, Huso, Dietz: Angiotensin II-dependent TGF-β signaling contributes to Loeys-Dietz syndrome vascular pathogenesis. in The Journal of clinical investigation 2014 (PubMed)
    Show all 2 references for ABIN4898037

  4. Human Polyclonal TGFBR2 Primary Antibody for FACS - ABIN4898025 : Rani, Smulian, Greaves, Hogan, Herbert: TGF-β limits IL-33 production and promotes the resolution of colitis through regulation of macrophage function. in European journal of immunology 2011 (PubMed)

  5. Mouse (Murine) Polyclonal TGFBR2 Primary Antibody for FACS - ABIN4898041 : Bodogai, Moritoh, Lee-Chang, Hollander, Sherman-Baust, Wersto, Araki, Miyoshi, Yang, Trinchieri, Biragyn: Immunosuppressive and Prometastatic Functions of Myeloid-Derived Suppressive Cells Rely upon Education from Tumor-Associated B Cells. in Cancer research 2015 (PubMed)

  6. Human Monoclonal TGFBR2 Primary Antibody for FACS - ABIN4898035 : Lages, Suffia, Velilla, Huang, Warshaw, Hildeman, Belkaid, Chougnet: Functional regulatory T cells accumulate in aged hosts and promote chronic infectious disease reactivation. in Journal of immunology (Baltimore, Md. : 1950) 2008 (PubMed)

  7. Mouse (Murine) Polyclonal TGFBR2 Primary Antibody for IF, IHC (p) - ABIN655799 : Liang, Li, Zhang, Cui, Quan, Yang: The anti-fibrotic effects of microRNA-153 by targeting TGFBR-2 in pulmonary fibrosis. in Experimental and molecular pathology 2015 (PubMed)

  8. Human Monoclonal TGFBR2 Primary Antibody for FACS - ABIN4898031 : Hermitte, Brunet de la Grange, Belloc, Praloran, Ivanovic: Very low O2 concentration (0.1%) favors G0 return of dividing CD34+ cells. in Stem cells (Dayton, Ohio) 2006 (PubMed)

  9. Cow (Bovine) Polyclonal TGFBR2 Primary Antibody for WB - ABIN2781999 : Song, Krebs, Danielpour: Novel permissive role of epidermal growth factor in transforming growth factor beta (TGF-beta) signaling and growth suppression. Mediation by stabilization of TGF-beta receptor type II. in The Journal of biological chemistry 2006 (PubMed)

More Antibodies against TGFBR2 Interaction Partners

Rhesus Monkey Transforming Growth Factor, beta Receptor II (70/80kDa) (TGFBR2) interaction partners

  1. Expression of microRNA miR (show MYLIP Antibodies)-155 was significantly upregulated in the oropharyngeal mucosa during chronic SIV infection and was coincident with downregulation of TGFbeta (show TGFB1 Antibodies) receptor 2 (TGFbeta (show TGFB1 Antibodies)-R2) and SMAD5 (show SMAD5 Antibodies).

Mouse (Murine) Transforming Growth Factor, beta Receptor II (70/80kDa) (TGFBR2) interaction partners

  1. In the presence of gadolinium and antibeta1 integrin antibody, collagen regulated the expression levels of Tgfbr1 (show TGFBR1 Antibodies), Tgfbr2 and Smad2 (show SMAD2 Antibodies)/3, but did not alter the phosphorylation of p38 (show CRK Antibodies), ERK1/2 (show MAPK1/3 Antibodies) or JNK (show MAPK8 Antibodies).

  2. Epithelial TGFbeta (show TGFB1 Antibodies) signaling via TGFBR2 does not contribute to the development of liver fibrosis or formation of hepatocellular carcinomas in mice, but restricts cholangiocyte proliferation to prevent cholangiocarcinoma development.

  3. The removal of Tgfbr2 and treatment with losartan both delayed the progression of articular cartilage degeneration induced by medial meniscus (DMM (show COL2A1 Antibodies)) compared with control littermates.

  4. Data (including data from studies in transgenic mice) suggest intraislet pancreatic duct cells are capable of giving rise to insulin (show INS Antibodies)-secreting beta-cells; Tgfbr2/transforming growth factor-beta type II receptor appears to be involved in this process.

  5. Elimination of TGF-betaIIR is not sufficient to completely prevent liver fibrosis. TGF-beta (show TGFB1 Antibodies)-independent mechanism of type I collagen production and suggest connective tissue growth factor (show CTGF Antibodies) as its potent mediator.

  6. Overexpression of TGFbeta1 (show TGFB1 Antibodies) promotes pulmonary inflammation, apoptosis and mortality via TGFbetaR2 in the developing mouse lung.

  7. Loss of smooth muscle cells Tgfbr2 disrupts TGF-beta (show TGFB1 Antibodies) signaling, acutely alters SMC (show DYM Antibodies) gene expression, and rapidly results in severe and durable aortopathy.

  8. Increased Tgfbr2 expression is associated with pulmonary fibrosis.

  9. High TGFBR2 expression is associated with pancreatic carcinoma.

  10. Suggest that miR (show MLXIP Antibodies)-370 acting via TbetaRII might play a potential role in hepatic IR injury, and inhibition of miR (show MLXIP Antibodies)-370 efficiently attenuated the damage to the liver.

Human Transforming Growth Factor, beta Receptor II (70/80kDa) (TGFBR2) interaction partners

  1. Study demonstrated that the TGFBR2 mutation was not present in the sample of cervico-cerebral artery dissection patients (CCAD); however, a positive association was identified between the MTHFR (show MTHFR Antibodies)-C677T polymorphism and genetically confirmed Mexican mestizo spontaneous CCAD patients

  2. The results showed that transfection of CD34 (show CD34 Antibodies)(+) cells with SiRNA targeting TGF-bRII and their co-culture with human bone marrow mesenchymal stromal cells (MSCs) could considerably increase the number of progenitors

  3. Cell invasion (matrigel) was reduced only in the Hs578T cells (p < 0.01). Silencing decreased the expression of the prometastatic molecules S100A4 (show S100A4 Antibodies) and TGFbetaR2 in both cell lines and CD44 (show CD44 Antibodies) in Hs578T cells. We conclude that ECM1 (show ECM1 Antibodies) is a key player in the metastatic process and regulates the actin cytoskeletal architecture of aggressive breast cancer cells at least in part via alterations in S100A4 (show S100A4 Antibodies) and Rho A (show RHOA Antibodies).

  4. Our study uncovers a novel mechanism that miR (show MLXIP Antibodies)-19a-3p/19b-3p inhibits autophagy-mediated fibrogenesis by targeting TGF-beta (show TGFB1 Antibodies) R II.

  5. TGFBR2 signaling can affect Notch1 (show NOTCH1 Antibodies) glycosylation via regulation of glycosyltransferase (show GTDC2 Antibodies) LFNG (show LFNG Antibodies) expression and provide a first mechanistic example for altered glycosylation in microsatellite instability colorectal tumor cells.

  6. CD44 (show CD44 Antibodies) and TGFBR2 are the functional targets of miR (show MLXIP Antibodies)-373, which are responsible for the tumor suppressive functions of miR (show MLXIP Antibodies)-373

  7. Polymorphism of TGFBR2 is associated with coronary artery disease.

  8. Exogenous expression of miR (show MLXIP Antibodies)-142-5p inhibitor resulted in a significant reduction of viral titer indicating proviral role of miR (show MLXIP Antibodies)-142-5p. Functional studies of hsa (show CD24 Antibodies)-miR (show MLXIP Antibodies)-142-5p identified its role in transforming growth factor beta (TGFbeta (show TGFB1 Antibodies)) signalling as TGFbeta (show TGFB1 Antibodies) receptor 2 and SMAD3 (show SMAD3 Antibodies) were degraded during both hsa (show CD24 Antibodies)-miR (show MLXIP Antibodies)-142-5p overexpression and rotavirus infection.

  9. Results found TGFBR2 to be significantly related to the regulated phosphoproteome in glioblastoma as a result of integrative upstream kinase/ regulator analyses and experimentally validated as a novel regulator of glioblastoma stem cells.

  10. Reduced expression of TGF-beta type II receptor and extracellular matrix components in response to reduced fibroblast size/mechanical force was fully reversed by restoring size/mechanical force

Cow (Bovine) Transforming Growth Factor, beta Receptor II (70/80kDa) (TGFBR2) interaction partners

  1. These results indicate that high plasma cholesterol levels may contribute to the pathogenesis of certain diseases (e.g., atherosclerosis) by suppressing TGF-beta (show TGFB1 Antibodies) responsiveness.

TGFBR2 Antigen Profile

Protein Summary

This gene encodes a member of the Ser/Thr protein kinase family and the TGFB receptor subfamily. The encoded protein is a transmembrane protein that has a protein kinase domain, forms a heterodimeric complex with another receptor protein, and binds TGF-beta. This receptor/ligand complex phosphorylates proteins, which then enter the nucleus and regulate the transcription of a subset of genes related to cell proliferation. Mutations in this gene have been associated with Marfan Syndrome, Loeys-Deitz Aortic Aneurysm Syndrome, and the development of various types of tumors. Alternatively spliced transcript variants encoding different isoforms have been characterized.

Gene names and symbols associated with TGFBR2

  • transforming growth factor, beta receptor II (70/80kDa) (TGFBR2) antibody
  • transforming growth factor, beta receptor II (TGFBR2) antibody
  • transforming growth factor, beta receptor II (70/80kDa) (LOC100220619) antibody
  • transforming growth factor beta receptor II (LOC100038019) antibody
  • transforming growth factor, beta receptor II (Tgfbr2) antibody
  • transforming growth factor, beta receptor II-like (LOC424261) antibody
  • 1110020H15Rik antibody
  • AAT3 antibody
  • AU042018 antibody
  • DNIIR antibody
  • FAA3 antibody
  • LDS1B antibody
  • LDS2B antibody
  • MFS2 antibody
  • RIIC antibody
  • RIIDN antibody
  • TAAD2 antibody
  • TBETA-RII antibody
  • TbetaR-II antibody
  • TbetaRII antibody
  • TBR-II antibody
  • TGF-beta 2 antibody
  • TGFbeta-RII antibody
  • TGFBR2 antibody
  • Tgfbr2T antibody
  • TGFBRII antibody
  • TGFR-2 antibody

Protein level used designations for TGFBR2

transforming growth factor, beta receptor II (70/80kDa) , transforming growth factor beta type II receptor , transforming growth factor, beta receptor II , transforming growth factor beta receptor 2 , TGF-beta receptor type-2 , TGF beta receptor type II , TGF-beta receptor type-2-like , TGF-beta receptor II , TGF-beta receptor type II , TGF-beta type II receptor , TGFR-2 , transforming growth factor-beta receptor type II , tbetaR-II , transforming growth factor beta receptor type II , transforming growth factor beta, receptor 2 , transforming growth factor, beta receptor 2 , transforming growth factor, beta receptor IIT , transforming growth factor-b type II receptor , transforming growth factor-beta type II receptor , TGF-beta receptor type IIB , transforming growth factor beta receptor type IIC

GENE ID SPECIES
460243 Pan troglodytes
477039 Canis lupus familiaris
494191 Ovis aries
703088 Macaca mulatta
100031897 Monodelphis domestica
100033860 Equus caballus
100076965 Ornithorhynchus anatinus
100404359 Callithrix jacchus
100459236 Pongo abelii
100482939 Ailuropoda melanoleuca
100220619 Taeniopygia guttata
100606849 Nomascus leucogenys
100038019 Sus scrofa
21813 Mus musculus
81810 Rattus norvegicus
396399 Gallus gallus
7048 Homo sapiens
535376 Bos taurus
424261 Gallus gallus
Selected quality suppliers for anti-TGFBR2 (TGFBR2) Antibodies
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