anti-Transforming Growth Factor, beta Receptor II (70/80kDa) (TGFBR2) Antibodies

TGFBR2 encodes a member of the Ser/Thr protein kinase family and the TGFB receptor subfamily. Additionally we are shipping TGFBR2 Kits (42) and TGFBR2 Proteins (31) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
TGFBR2 21813 Q62312
TGFBR2 81810 P38438
TGFBR2 7048 P37173
How to order from antibodies-online
  • +1 877 302 8632
  • +1 888 205 9894 (toll-free)
  • Order online
  • orders@antibodies-online.com

Top anti-TGFBR2 Antibodies at antibodies-online.com

Showing 10 out of 249 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Cow Rabbit Un-conjugated WB <b>WB Suggested Anti-TGFBR2 Antibody Titration: </b>5.0ug/ml<br><b>Positive Control: </b>HepG2 cell lysate 100 μL Log in to see 2 to 3 Days
$229.00
Details
Human Rabbit Un-conjugated WB 100 μg Log in to see 4 to 6 Days
$240.00
Details
Human Goat Un-conjugated CyTOF, ELISA (Capture), FACS, IHC, Neut, WB TGF-beta 1 Inhibition of IL-4-dependent Cell Proliferation and Neutralization by Human TGF-beta RII Antibody. Recombinant Human TGF-beta 1. The ND50 is typically 10-20 ug/mL. Detection of TGF-beta RII in Human Lymphocytes by Flow Cytometry. Human blood-derived lymphocytes were labeled with Goat Anti-Human TGF-beta RII Antigen Affinity-purified Poly-clonal Antibody. 250 μg Log in to see 8 to 9 Days
$414.75
Details
Human Rabbit Un-conjugated WB Western blot analysis of TGFBR2 (pS225) expression in A549 (A), NIH3T3L1 (B), KNRK (C), HepG2 (D) whole cell lysates. 200 μL Log in to see 13 to 14 Days
$575.00
Details
Human Mouse Fluorescein FACS Detection of TGF-beta RII in NS0 Mouse Cell Line Transfected with TGF-beta RII by Flow Cytometry. NS0 mouse myeloma cell line transfected with TGF-beta RII was stained with Mouse Anti-Human TGF-beta RII Fluorescein-conjugated Monoclonal Antibody. Detection of TGF-beta RII in NS0 Mouse Cell Line Transfected with TGF-beta RII by Flow Cytometry. NS0 mouse myeloma cell line transfected with TGF-beta RII was stained with Mouse Anti-Human TGF-beta RII Fluorescein-conjugated Monoclonal Antibody. 25 Tests Log in to see 8 to 9 Days
$131.25
Details
Human Mouse PE FACS Detection of TGF-beta RII in NS0 Mouse Cell Line transfected with TGF-beta RII by Flow Cytometry. NS0 mouse myeloma cell line transfected with TGF-beta RII was stained with Mouse Anti-Human TGF-beta RII PE-conjugated Monoclonal Antibody. Detection of TGF-beta RII in NS0 Mouse Cell Line transfected with TGF-beta RII by Flow Cytometry. NS0 mouse myeloma cell line transfected with TGF-beta RII was stained with Mouse Anti-Human TGF-beta RII PE-conjugated Monoclonal Antibody. 25 Tests Log in to see 8 to 9 Days
$160.65
Details
Mouse Goat Fluorescein FACS Detection of TGF-beta RII in Mouse Splenocytes by Flow Cytometry. Mouse splenocytes were stained with Goat Anti-Mouse TGF-beta RII Fluorescein-conjugated Antigen Affinity-purified Polyclonal Antibody. Detection of TGF-beta RII in Mouse Splenocytes by Flow Cytometry. Mouse splenocytes were stained with Goat Anti-Mouse TGF-beta RII Fluorescein-conjugated Antigen Affinity-purified Polyclonal Antibody. 25 Tests Log in to see 8 to 9 Days
$131.25
Details
Mouse Goat PE FACS Detection of TGF-beta RII in Mouse Splenocytes by Flow Cytometry. Mouse splenocytes were stained with Goat Anti-Mouse TGF-beta RII PE-conjugated Antigen Affinity-purified Polyclonal Antibody. Detection of TGF-beta RII in Mouse Splenocytes by Flow Cytometry. Mouse splenocytes were stained with Goat Anti-Mouse TGF-beta RII PE-conjugated Antigen Affinity-purified Polyclonal Antibody. 25 Tests Log in to see 8 to 9 Days
$160.65
Details
Human Goat PE FACS Detection of TGF-beta RII in Human Blood Lymphocytes by Flow Cytometry. Human peripheral blood lymphocytes were stained with Goat Anti-Human TGF-beta RII PE-conjugated Antigen Affinity-purified Polyclonal Antibody. Detection of TGF-beta RII in Human Blood Lymphocytes by Flow Cytometry. Human peripheral blood lymphocytes were stained with Goat Anti-Human TGF-beta RII PE-conjugated Antigen Affinity-purified Polyclonal Antibody. 25 Tests Log in to see 8 to 9 Days
$160.65
Details
Mouse Goat Allophycocyanin FACS Detection of TGF-beta RII in Mouse Splenocytes by Flow Cytometry. Mouse splenocytes were stained with Goat Anti-Mouse TGF-beta RII APC-conjugated Antigen Affinity-purified Polyclonal Antibody. Detection of TGF-beta RII in Mouse Splenocytes by Flow Cytometry. Mouse splenocytes were stained with Goat Anti-Mouse TGF-beta RII APC-conjugated Antigen Affinity-purified Polyclonal Antibody. 25 Tests Log in to see 8 to 9 Days
$179.55
Details

TGFBR2 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
Mouse (Murine) , , , ,
, ,
,
, , , , , , , , , , , , , , , , , , ,
Rat (Rattus) , , , ,


, , , , , , , , , , , , ,
Human , , , ,
, , ,
,
, , , , , , , , , , , , , , , , , , ,

Top referenced anti-TGFBR2 Antibodies

  1. Human Polyclonal TGFBR2 Primary Antibody for CyTOF, ELISA (Capture) - ABIN4900595 : Wu, Majeed, Evans, Camus, Wong, Schollmeier, Park, Muppidi, Reboldi, Parham, Cyster, Brodsky: Clathrin light chains' role in selective endocytosis influences antibody isotype switching. in Proceedings of the National Academy of Sciences of the United States of America 2016 (PubMed)
    Show all 11 Pubmed References

  2. Mouse (Murine) Polyclonal TGFBR2 Primary Antibody for FACS - ABIN4898045 : Lewis, Macal, Hesser, Zuñiga et al.: Constitutive but not inducible attenuation of transforming growth factor β signaling increases natural killer cell responses without directly affecting dendritic cells early after persistent viral ... in Journal of virology 2015 (PubMed)
    Show all 6 Pubmed References

  3. Mouse (Murine) Polyclonal TGFBR2 Primary Antibody for FACS - ABIN4898046 : Rani, Smulian, Greaves, Hogan, Herbert: TGF-β limits IL-33 production and promotes the resolution of colitis through regulation of macrophage function. in European journal of immunology 2011 (PubMed)
    Show all 6 Pubmed References

  4. Human Polyclonal TGFBR2 Primary Antibody for IF (p), IHC (p) - ABIN725225 : Abdelmagid, Belcher, Moussa, Lababidi, Sondag, Novak, Sanyurah, Frara, Razmpour, Del Carpio-Cano, Safadi: Mutation in osteoactivin decreases bone formation in vivo and osteoblast differentiation in vitro. in The American journal of pathology 2014 (PubMed)
    Show all 3 Pubmed References

  5. Human Polyclonal TGFBR2 Primary Antibody for ICC, IHC (fro) - ABIN407857 : Phatnani, Guarnieri, Friedman, Carrasco, Muratet, OKeeffe, Nwakeze, Pauli-Behn, Newberry, Meadows, Tapia, Myers, Maniatis: Intricate interplay between astrocytes and motor neurons in ALS. in Proceedings of the National Academy of Sciences of the United States of America 2013 (PubMed)
    Show all 2 Pubmed References

  6. Mouse (Murine) Polyclonal TGFBR2 Primary Antibody for FACS, WB - ABIN4900596 : Denton, Zheng, Evans, Shi-wen, Ong, Fisher, Lazaridis, Abraham, Black, de Crombrugghe et al.: Fibroblast-specific expression of a kinase-deficient type II transforming growth factor beta (TGFbeta) receptor leads to paradoxical activation of TGFbeta signaling pathways with fibrosis in ... in The Journal of biological chemistry 2003 (PubMed)
    Show all 2 Pubmed References

  7. Mouse (Murine) Polyclonal TGFBR2 Primary Antibody for CyTOF, FACS - ABIN4900597 : Liu, Bi, Xue, Zhang, Yang, Chen, Lu, Zhang, Liu, Wang, Wang, Chu, Yang: Dendritic cell SIRT1-HIF1α axis programs the differentiation of CD4+ T cells through IL-12 and TGF-β1. in Proceedings of the National Academy of Sciences of the United States of America 2015 (PubMed)
    Show all 2 Pubmed References

  8. Mouse (Murine) Polyclonal TGFBR2 Primary Antibody for FACS - ABIN4898037 : Gallo, Loch, Habashi, Calderon, Chen, Bedja, van Erp, Gerber, Parker, Sauls, Judge, Cooke, Lindsay, Rouf, Myers, ap Rhys, Kent, Norris, Huso, Dietz: Angiotensin II-dependent TGF-β signaling contributes to Loeys-Dietz syndrome vascular pathogenesis. in The Journal of clinical investigation 2014 (PubMed)
    Show all 2 Pubmed References

  9. Mouse (Murine) Polyclonal TGFBR2 Primary Antibody for FACS - ABIN4898038 : Zhou, Dong, Zhang, Chen, Zhu, Li, Song, Xu, Zhang, Yang, Li, Liu, Sun: MicroRNAs are implicated in the suppression of CD4+CD25− conventional T cell proliferation by CD4+CD25+ regulatory T cells. in Molecular immunology 2015 (PubMed)
    Show all 2 Pubmed References

  10. Mouse (Murine) Polyclonal TGFBR2 Primary Antibody for IF, IHC (p) - ABIN655799 : Liang, Li, Zhang, Cui, Quan, Yang: The anti-fibrotic effects of microRNA-153 by targeting TGFBR-2 in pulmonary fibrosis. in Experimental and molecular pathology 2015 (PubMed)

More Antibodies against TGFBR2 Interaction Partners

Rhesus Monkey Transforming Growth Factor, beta Receptor II (70/80kDa) (TGFBR2) interaction partners

  1. Expression of microRNA miR (show MYLIP Antibodies)-155 was significantly upregulated in the oropharyngeal mucosa during chronic SIV infection and was coincident with downregulation of TGFbeta (show TGFB1 Antibodies) receptor 2 (TGFbeta (show TGFB1 Antibodies)-R2) and SMAD5 (show SMAD5 Antibodies).

Mouse (Murine) Transforming Growth Factor, beta Receptor II (70/80kDa) (TGFBR2) interaction partners

  1. removing TGF-b type II receptor in DA neurons also disrupts the balance in TGF-b1 expression in DA neurons and neighboring GABAergic neurons, which increases inhibitory input, reduces excitatory synaptic input, and alters phasic firing patterns in DA neurons

  2. PAR1 (show F2R Antibodies) in its inactive unligated state functions as a scaffold for TGFbetaRII to downregulate TGF-beta (show TGFB1 Antibodies) signaling, and thereby promote embryonic stem cell transition to functional endothelial cells.

  3. Cell-intrinsic TGFbeta-RII signaling limits CD4 (show CD4 Antibodies) T cell proliferation but not prototypical T helper subset differentiation early after chronic lymphocytic choriomeningitis virus infection.

  4. These results suggest that DMSO, a fusogenic substance, enhances TGF-beta (show TGFB1 Antibodies) activity presumably by inducing fusion of cytoplasmic vesicles (containing TbetaR-II) and the plasma membrane, resulting in increased localization of TbetaR-II to non-lipid raft microdomains where canonical signaling occurs.

  5. USP11 (show USP11 Antibodies) may contribute to the pathogenesis of pulmonary fibrosis by stabilization of TbetaRII and promotion of TGFbeta (show TGFB1 Antibodies)-1 signaling.

  6. both GDF-15 (show GDF15 Antibodies) and TGF-beta1 (show TGFB1 Antibodies) counteract chemokine (show CCL1 Antibodies)-induced integrin activation on neutrophils via the ALK-5 (show TGFBR1 Antibodies)/TGF-betaRII heterodimer.

  7. Knockout of the TGFbeta (show TGFB1 Antibodies) receptor in proopiomelanocortin (show POMC Antibodies) neurons counteracts the hypertensive effect of not only TGFbeta (show TGFB1 Antibodies) but also mtDNA excess, while the hypertensive action of central mtDNA can be blocked pharmacologically by a TGFbeta (show TGFB1 Antibodies) receptor antagonist or genetically by TGFbeta (show TGFB1 Antibodies) receptor knockout.

  8. Postnatal disruption of Tgfbr2 gene compromises extracellular matrix properties and promotes aortic dissection, which can be prevented by rapamycin treatment.

  9. Gasdermin C is upregulated by inactivation of Tgfbr2 in the presence of mutated Apc (show APC Antibodies), promoting colorectal cancer cell proliferation.

  10. In the presence of gadolinium and antibeta1 integrin antibody, collagen regulated the expression levels of Tgfbr1 (show TGFBR1 Antibodies), Tgfbr2 and Smad2 (show SMAD2 Antibodies)/3, but did not alter the phosphorylation of p38 (show CRK Antibodies), ERK1/2 (show MAPK1/3 Antibodies) or JNK (show MAPK8 Antibodies).

Human Transforming Growth Factor, beta Receptor II (70/80kDa) (TGFBR2) interaction partners

  1. Inhibition of TGFBR2 had the similar effect as miR (show MLXIP Antibodies)-9 overexpression.

  2. we describe and characterize the functional impact of a novel VUS in the TGFBR2 kinase domain (c.1255G>T; p.Val419Leu), in a patient with the clinical diagnosis of Marfan syndrome spectrum. Our results establish that the V419L variant leads to aberrant TGF-beta (show TGFB1 Antibodies) signaling and confirm the diagnosis of Loeys-Dietz syndrome in this patient.

  3. Apo (show C9orf3 Antibodies) and inhibitor-bound TGFBR2 kinase structures are presented at high resolution (<2 A).

  4. Aortic diseases in patients with TGFBR1 (show TGFBR1 Antibodies) or TGFBR2 mutations show the same prevalence of systemic features and the same global survival.

  5. TGF-beta (show TGFB1 Antibodies) type I, II, and III receptors were all identified in pregnant serum; all were substantially elevated in early-onset but not late-onset PE. Endoglin (show ENG Antibodies) was increased in both subtypes.

  6. Although TGFbeta1 (show TGFB1 Antibodies)/2 receptors are downregulated in breast cancer, their expression in tumors is an indicator of aggressive breast cancer phenotype.

  7. this is the first clinical report to demonstrate a potential causal association between TGFB2 (show TGFB2 Antibodies) gene mutations and aortic root dilatation in combination with the myxomatous degeneration of both atrioventricular valves.

  8. USP11 (show USP11 Antibodies) may contribute to the pathogenesis of pulmonary fibrosis by stabilization of TbetaRII and promotion of TGFbeta (show TGFB1 Antibodies)-1 signaling.

  9. Molecular modeling and molecular dynamic simulation of the effects of variants in the TGFBR2 kinase domain as a paradigm for interpretation of variants obtained by next generation sequencing.

  10. A novel mutation in the TGFBR2 gene was identified in a patient with Loeys-Dietz syndrome.

Cow (Bovine) Transforming Growth Factor, beta Receptor II (70/80kDa) (TGFBR2) interaction partners

  1. These results indicate that high plasma cholesterol levels may contribute to the pathogenesis of certain diseases (e.g., atherosclerosis) by suppressing TGF-beta (show TGFB1 Antibodies) responsiveness.

TGFBR2 Antigen Profile

Protein Summary

This gene encodes a member of the Ser/Thr protein kinase family and the TGFB receptor subfamily. The encoded protein is a transmembrane protein that has a protein kinase domain, forms a heterodimeric complex with another receptor protein, and binds TGF-beta. This receptor/ligand complex phosphorylates proteins, which then enter the nucleus and regulate the transcription of a subset of genes related to cell proliferation. Mutations in this gene have been associated with Marfan Syndrome, Loeys-Deitz Aortic Aneurysm Syndrome, and the development of various types of tumors. Alternatively spliced transcript variants encoding different isoforms have been characterized.

Gene names and symbols associated with TGFBR2

  • transforming growth factor beta receptor 2 (TGFBR2) antibody
  • transforming growth factor, beta receptor II (Tgfbr2) antibody
  • transforming growth factor, beta receptor 2 (Tgfbr2) antibody
  • anti-Mullerian hormone receptor, type II (AMHR2) antibody
  • 1110020H15Rik antibody
  • AAT3 antibody
  • AU042018 antibody
  • DNIIR antibody
  • FAA3 antibody
  • LDS1B antibody
  • LDS2B antibody
  • MFS2 antibody
  • RIIC antibody
  • RIIDN antibody
  • TAAD2 antibody
  • TBETA-RII antibody
  • TbetaR-II antibody
  • TbetaRII antibody
  • TBR-II antibody
  • TGF-beta 2 antibody
  • TGFbeta-RII antibody
  • TGFBR2 antibody
  • Tgfbr2T antibody
  • TGFBRII antibody
  • TGFR-2 antibody

Protein level used designations for TGFBR2

transforming growth factor, beta receptor II (70/80kDa) , transforming growth factor beta type II receptor , transforming growth factor, beta receptor II , transforming growth factor beta receptor 2 , TGF-beta receptor type-2 , TGF beta receptor type II , TGF-beta receptor type-2-like , TGF-beta receptor II , TGF-beta receptor type II , TGF-beta type II receptor , TGFR-2 , transforming growth factor-beta receptor type II , tbetaR-II , transforming growth factor beta receptor type II , transforming growth factor beta, receptor 2 , transforming growth factor, beta receptor 2 , transforming growth factor, beta receptor IIT , transforming growth factor-b type II receptor , transforming growth factor-beta type II receptor , TGF-beta receptor type IIB , transforming growth factor beta receptor type IIC

GENE ID SPECIES
460243 Pan troglodytes
477039 Canis lupus familiaris
494191 Ovis aries
703088 Macaca mulatta
100031897 Monodelphis domestica
100033860 Equus caballus
100076965 Ornithorhynchus anatinus
100404359 Callithrix jacchus
100459236 Pongo abelii
100482939 Ailuropoda melanoleuca
100220619 Taeniopygia guttata
100606849 Nomascus leucogenys
100038019 Sus scrofa
21813 Mus musculus
81810 Rattus norvegicus
396399 Gallus gallus
7048 Homo sapiens
535376 Bos taurus
424261 Gallus gallus
Selected quality suppliers for anti-TGFBR2 (TGFBR2) Antibodies
Did you look for something else?