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This locus encodes the transforming growth factor (TGF)-beta type III receptor. Additionally we are shipping TGFBR3 Kits (13) and TGFBR3 Proteins (10) and many more products for this protein.
Showing 10 out of 104 products:
Human Monoclonal TGFBR3 Primary Antibody for ELISA, WB - ABIN1724752
Jiang, Liu, Lei, You, Zhou, Zhang: [Defective expression of TGFBR3 gene and its molecular mechanisms in non-small cell lung cancer cell lines]. in Zhongguo fei ai za zhi = Chinese journal of lung cancer 2010
Show all 2 references for ABIN1724752
Human Monoclonal TGFBR3 Primary Antibody for FACS, ELISA - ABIN1724751
Lambert, Huang, Mythreye, Blobe: The type III transforming growth factor-? receptor inhibits proliferation, migration, and adhesion in human myeloma cells. in Molecular biology of the cell 2011
Show all 2 references for ABIN1724751
Mouse (Murine) Polyclonal TGFBR3 Primary Antibody for ELISA - ABIN2001105
Rotzer, Roth, Lutz, Lindemann, Sebald, Knaus: Type III TGF-beta receptor-independent signalling of TGF-beta2 via TbetaRII-B, an alternatively spliced TGF-beta type II receptor. in The EMBO journal 2001
Human Polyclonal TGFBR3 Primary Antibody for ELISA - ABIN449737
Woszczyk, Gola, Jurzak, Mazurek, Myka?a-Cie?la, Wilczok: Expression of TGF beta1 genes and their receptor types I, II, and III in low- and high-grade malignancy non-Hodgkin's lymphomas. in Medical science monitor : international medical journal of experimental and clinical research 2004
Chicken Polyclonal TGFBR3 Primary Antibody for IHC (p), IP - ABIN265019
Brown, Boyer, Runyan, Barnett: Requirement of type III TGF-beta receptor for endocardial cell transformation in the heart. in Science (New York, N.Y.) 1999
Human Polyclonal TGFBR3 Primary Antibody for IF, ELISA - ABIN1533411
Gregory, Barlow, McLay, Kaul, Swarbreck, Dunham, Scott, Howe, Woodfine, Spencer, Jones, Gillson, Searle, Zhou, Kokocinski, McDonald, Evans, Phillips, Atkinson, Cooper, Jones, Hall, Andrews, Lloyd et al.: The DNA sequence and biological annotation of human chromosome 1. ... in Nature 2006
Inhibition of genes for betaglycan and FIBP (show FIBP Antibodies) in granulosa cells in vitro suggests that they inhibit estradiol production in regressing subordinate follicles.
Results show decreased TbetaRIII expression with hepatocellullar carcinoma (HCC (show FAM126A Antibodies)) progression leading to the activation of Smad2 (show SMAD2 Antibodies) and suggest that TbetaRIII acts as a suppressive factor in regulating the migration and invasion of HCC (show FAM126A Antibodies), by inhibiting Smad2 (show SMAD2 Antibodies) and Akt (show AKT1 Antibodies) pathways.
Study shows that TbetaRIII expression is significantly decreased in salivary glands adenoid cystic carcinoma (ACC) patients and defines TbetaRIII as a biomarker exerting antitumor action on ACC progression.
No correlation of loss of heterozygosity at the TGFBR3 locus with clinicopathological parameters suggests that allelic imbalance may be an early genetic event during neoplastic transformation of human endometrium.
Study shows that GDF10 (show GDF10 Antibodies) is down-regulated in patients with oral squamous cell carcinoma, and is an independent risk factor for overall survival. Its expression is regulated by TGFBR3 which shares the signaling inhibiting epithelial-mesenchymal transition.
rs1192415 of TGFBR3 is associated with primary open angle glaucoma.
results suggest overexpression of TbetaRIII receptor restored TGF-beta1 (show TGFB1 Antibodies) sensitivity in CAL (show FBLIM1 Antibodies)-27 cells
The presence of the index SNP rs1192415 (TGFBR3-CDC7 (show CDC7 Antibodies)) was associated with visual field progression in POAG (primary open-angle glaucoma) patients.
Inhibiting ectodomain shedding of TbetaRIII increased TGF-beta (show TGFB1 Antibodies) responsiveness and abrogated TbetaRIII's ability to inhibit breast cancer cell migration and invasion.
data suggest complex or phenotype specific association of cryptorchidism with TGFBR3 and the gubernaculum as a potential target of TGFbeta (show TGFB1 Antibodies) signaling
Data indicate that TGF-beta2 (TGFB2 (show TGFB2 Antibodies)) and TGF beta (show TGFB1 Antibodies) type III receptor (TGFBR3) are target genes of miR (show MLXIP Antibodies)-193b in chondrogenesis.
Pro-fibrotic cardiac effect of miR (show MLXIP Antibodies)-328 was mediated by down-regulating TGFbR3 and up-regulating TGFb1 (show TGFB1 Antibodies).
These data demonstrate that TbetaRIII regulates BMP-mediated signaling and biological effects, primarily through the ligand sequestration effects of sTbetaRIII in normal and cancerous mammary epithelial cells.
Glucocorticoids recruit Tgfbr3 and Smad1 (show SMAD1 Antibodies) to shift transforming growth factor-beta signaling from the Tgfbr1 (show TGFBR1 Antibodies)/Smad2 (show SMAD2 Antibodies)/3 axis to the Acvrl1 (show ACVRL1 Antibodies)/Smad1 (show SMAD1 Antibodies) axis in lung fibroblasts.
work reveals a 'seed and soil' mechanism where TGF-beta2 (show TGFB2 Antibodies) and TGF-beta (show TGFB1 Antibodies)-RIII signalling through p38alpha (show MAPK14 Antibodies)/beta regulates DTC dormancy and defines restrictive (BM) and permissive (lung) microenvironments for HNSCC metastasis
TGFBR3 mediated suppression of cancer progression includes effects on the tumor immune microenvironment.
Loss of Tgfbr3 compromises the functions of TGFbeta2 in the differentiating fetal testis.
A novel reciprocal loop between miR (show MLXIP Antibodies)-21 and TGFbetaRIII in cardiac fibrosis caused by myocardial infarction in mice.
the relative roles of TGFbetaR3-dependent and -independent signaling in the actions of BMP2 (show BMP2 Antibodies) on epicardial cell behavior and demonstrate the critical role of TGFbetaR3 in mediating BMP2 (show BMP2 Antibodies)-stimulated invasion.
TGFBR3 can prevent hypoxia-induced injury in neonatal mice cardiac fibroblasts by negative regulation of TGF-beta (show TGFB1 Antibodies) signaling.
Data present the 2.0-A resolution crystal structure of the betaglycan ZP-C region in combination with a downstream region known as the external hydrophobic patch.
This study provides evidence that the expressions of inhibin alpha subunit (show INHA Antibodies) and betaglycan are inferior in cystic follicles, and this may be caused by the decrease in FSH (show BRD2 Antibodies) in the presence of a cystic follicle.
This locus encodes the transforming growth factor (TGF)-beta type III receptor. The encoded receptor is a membrane proteoglycan that often functions as a co-receptor with other TGF-beta receptor superfamily members. Ectodomain shedding produces soluble TGFBR3, which may inhibit TGFB signaling. Decreased expression of this receptor has been observed in various cancers. Alternatively spliced transcript variants encoding different isoforms have been identified for this gene.
transforming growth factor, beta receptor III
, transforming growth factor, beta receptor III (betaglycan, 300kDa)
, transforming growth factor beta receptor type 3-like
, TGF-beta receptor type 3
, TGF-beta receptor type III
, betaglycan proteoglycan
, transforming growth factor beta receptor type 3
, transforming growth factor, beta receptor 3
, TGF-beta type III receptor
, transforming growth factor beta receptor III
, transforming growth factor-beta type III receptor