anti-Transgelin (TAGLN) Antibodies

The protein encoded by TAGLN is a transformation and shape-change sensitive actin cross-linking/gelling protein found in fibroblasts and smooth muscle. Additionally we are shipping Transgelin Kits (19) and Transgelin Proteins (17) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
TAGLN 6876 Q01995
TAGLN 21345 P37804
TAGLN 25123 P31232
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Top anti-Transgelin Antibodies at antibodies-online.com

Showing 10 out of 182 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Cow Rabbit Un-conjugated IHC, WB Immunohistochemistry with Spleen tissue at an antibody concentration of 5µg/ml using anti-Tagln antibody (ARP48222_P050) WB Suggested Anti-Tagln <br /> Antibody Titration: 1 µg/mL <br /> Positive Control: Rat Lung lysate 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Rabbit Un-conjugated FACS, IHC (p), WB Western blot analysis of TAGLN antibody (C-term) (ABIN390627) in mouse bladder tissue lysates (35 µg/lane). TAGLN (arrow) was detected using the purified polyclonal antibody. Formalin-fixed and paraffin-embedded human skeletal muscle reacted with TAGLN Antibody (C-term), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Goat Un-conjugated ELISA, WB ABIN153392 staining (0.03ug/ml) of HeLa cell lysate (RIPA buffer, 35ug total protein per lane). Primary incubated for 1 hour. Detected by Western blot using chemiluminescence. ABIN153392 staining (0.001ug/ml) of Human Placenta lysate (RIPA buffer, 35ug total protein per lane). Primary incubated for 1 hour. Detected by western blot using chemiluminescence. 0.1 mg Log in to see 7 to 9 Days
$408.19
Details
Human Rabbit Un-conjugated ICC, IF, IHC, IHC (p), IP, WB Immunocytochemistry/Immunofluorescence: Transgelin/TAGLN/SM22 alpha Antibody [NBP1-33003] - Analysis of paraformaldehyde-fixed HeLa, using NBP1-33003. Immunohistochemistry-Paraffin: Transgelin/TAGLN/SM22 alpha Antibody [NBP1-33003] - Paraffin-embedded rat stomach Transgelin antibody diluted at 1:500. 0.1 mL Log in to see 7 to 9 Days
$447.56
Details
Human Rabbit Un-conjugated FACS, IHC (p), WB Western blot analysis of TAGLN antibody (N-term) (ABIN390626) in SK-Br-3 cell line lysates (35 µg/lane). TAGLN (arrow) was detected using the purified polyclonal antibody. Formalin-fixed and paraffin-embedded human skeletal muscle reacted with TAGLN Antibody (N-term), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Rabbit Un-conjugated EIA, WB Western blot analysis of TAGLN antibody (C-term) in mouse bladder tissue lysates (35ug/lane). TAGLN (arrow) was detected using the purified Pab. 0.4 mL Log in to see 6 to 8 Days
$390.50
Details
Human Rabbit Un-conjugated EIA, WB Western blot analysis of TAGLN antibody (N-term) in SK-Br-3 cell line lysates (35ug/lane). TAGLN (arrow) was detected using the purified Pab. 0.4 mL Log in to see 6 to 8 Days
$390.50
Details
Human Mouse Un-conjugated WB Western Blot analysis of TAGLN expression in transfected 293T cell line by TAGLN monoclonal antibody (M01), clone 1E2. Lane 1: TAGLN transfected lysate(22.6 KDa). Lane 2: Non-transfected lysate. 0.1 mg Log in to see 8 to 11 Days
$450.00
Details
Human Rabbit Un-conjugated ICC, IF, IHC, IHC (p), WB Western Blot: Transgelin/TAGLN/SM22 alpha Antibody  - Analysis in human heart tissue. Immunohistochemistry-Paraffin: Transgelin/TAGLN/SM22 alpha Antibody  - Staining of human gall bladder shows strong cytoplasmic positivity in smooth muscle cells. 0.1 mL Log in to see 10 to 13 Days
$439.69
Details
Bat Goat Un-conjugated IHC (p), ELISA, WB Human Uterus (formalin-fixed, paraffin-embedded) stained with TAGLN antibody ABIN337285 at 5 ug/ml followed by biotinylated anti-goat IgG secondary antibody ABIN481715, alkaline phosphatase-streptavidin and chromogen. 50 μg Log in to see 7 to 9 Days
$451.00
Details

TAGLN Antibodies by Reactivity, Application, Clonality and Conjugate

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Top referenced anti-Transgelin Antibodies

  1. Human Polyclonal Transgelin Primary Antibody for ELISA, WB - ABIN153392 : Nishida, Kitami, Abe, Hiwada: Gene cloning and nucleotide sequence of SM22 alpha from the chicken gizzard smooth muscle. in Biochemistry international 1991 (PubMed)
    Show all 19 Pubmed References

  2. Human Polyclonal Transgelin Primary Antibody for ELISA, WB - ABIN185188 : Donati, Marseglia, Magi, Serratì, Cencetti, Bernacchioni, Nannetti, Benelli, Brunelli, Torricelli, Cossu, Bruni: Sphingosine 1-phosphate induces differentiation of mesoangioblasts towards smooth muscle. A role for GATA6. in PLoS ONE 2011 (PubMed)
    Show all 5 Pubmed References

  3. Human Monoclonal Transgelin Primary Antibody for ELISA - ABIN948518 : Canducci, Saita, Foglieni, Piscopiello, Chiesa, Colombo, Cianflone, Maseri, Clementi, Burioni: Cross-reacting antibacterial auto-antibodies are produced within coronary atherosclerotic plaques of acute coronary syndrome patients. in PLoS ONE 2012 (PubMed)

  4. Human Polyclonal Transgelin Primary Antibody for ICC, IF - ABIN4362001 : Isella, Terrasi, Bellomo, Petti, Galatola, Muratore, Mellano, Senetta, Cassenti, Sonetto, Inghirami, Trusolino, Fekete, De Ridder, Cassoni, Storme, Bertotti, Medico: Stromal contribution to the colorectal cancer transcriptome. in Nature genetics 2015 (PubMed)

  5. Human Polyclonal Transgelin Primary Antibody for ICC, IF - ABIN442948 : Shi, Srivastava, Kanasaki, He, Kitada, Nagai, Nitta, Takagi, Kanasaki, Koya: Interactions of DPP-4 and integrin β1 influences endothelial-to-mesenchymal transition. in Kidney international 2015 (PubMed)

More Antibodies against Transgelin Interaction Partners

Human Transgelin (TAGLN) interaction partners

  1. Data (including data from studies using cells cultured from transgenic/knockout mice) suggest that expression and degradation of transgelin in myofibroblasts and keratinocytes are regulated by mechanical tension in cytoskeleton produced by myosin II motor in response to stiffness of culture matrix/extracellular matrix.

  2. transgelin (TAGLN), a transforming growth factor beta (TGFbeta (show TGFB1 Antibodies))-inducible gene, was identified as an upregulated gene during in vitro osteoblastic and adipocytic differentiation of human bone marrow-derived stromal (skeletal) stem cells

  3. regulates vasculogenic mimicry in breast cancer cells by enhancing interleukin-8 (show IL8 Antibodies) uptake

  4. Serum concentrations of CK-18 (show KRT18 Antibodies) fragments and transgelin-2 (show TAGLN2 Antibodies) correlate with the severity of NAFLD (show TSC2 Antibodies), but not with obesity.

  5. Increases or decreases in transgelin levels have reciprocal effects on tumor cell behavior, with higher expression promoting metastasis

  6. activated AKT (show AKT1 Antibodies) and JNK (show MAPK8 Antibodies) signaling pathways promote the overexpression of transgelin

  7. Cofilin-1 (show CFL1 Antibodies) and transgelin may play roles in the carcinogenesis and development of esophageal squamous cell carcinoma

  8. Both tissue and salivary transgelin mRNA were closely correlated with various important clinicopathological parameters and were independent prognosis factors for oral squamous cell carcinoma.

  9. SM22alpha is a phosphorylation-regulated (show PHAX Antibodies) suppressor of IKK (show CHUK Antibodies)-IkappaBalpha (show NFKBIA Antibodies)-NF-kappaB (show NFKB1 Antibodies) signaling cascades.

  10. EZH2 (show EZH2 Antibodies) regulates the chromatin structure at the TAGLN promoter through tri (show VANGL2 Antibodies)-methylation of H3K27, acting as an epigenetic integrator of IL-1beta (show IL1B Antibodies) and TGFbeta2 signaling.

Mouse (Murine) Transgelin (TAGLN) interaction partners

  1. Data (including data from studies using cells cultured from transgenic/knockout mice) suggest that expression and degradation of transgelin in myofibroblasts and keratinocytes are regulated by mechanical tension in cytoskeleton produced by myosin II motor in response to stiffness of culture matrix/extracellular matrix.

  2. Targeted elimination of TGFbetaR2 in TAGLN(+) cells impairs midline closure and prevents the correct subsequent patterning of the musculature and skeletal components.

  3. SM22alpha is a phosphorylation-regulated (show PHAX Antibodies) suppressor of IKK (show CHUK Antibodies)-IkappaBalpha (show NFKBIA Antibodies)-NF-kappaB (show NFKB1 Antibodies) signaling cascades.

  4. SM22alpha promotes ubiquitination and degradation of MKP3 (show DUSP6 Antibodies). SM22alpha facilitates AngII-induced contraction by maintenance of ERK1/2 (show MAPK1/3 Antibodies) signaling.

  5. TRAF6 (show TRAF6 Antibodies)-SM22alpha-G6PD (show G6PD Antibodies) pathway is a novel mechanism underlying the association between glucose metabolism and VSMC survival, which is beneficial for vascular repair after injury but facilitates atherosclerotic plaque stability.

  6. Absent/lower SM22 alpha levels favor an increase in parietal epithelial cell transition cells and PECs expressing a progenitor marker, and a lower epithelial mesenchymal transformation rate versus SM22alpha+/+mice, where SM22 levels are increased in PECs.

  7. SM22alpha-regulated molecular pathways contribute to vascular pathology.

  8. Histological analysis did not reveal calcium deposits in the aortic roots of SM22alpha-Rankl (show TNFSF11 Antibodies) ( tg ) mice

  9. Data show that formation of a Krupple-like factor KLF4 (show KLF4 Antibodies), pELK-1, and histone de-acetylase 2 (HDAC2 (show HDAC2 Antibodies)) multiprotein complex dependent on the SM22alpha G/C Repressor element.

  10. Data suggest that SM22alpha expression in renal tissues might be a hallmark of kidney diseases.

Transgelin (TAGLN) Antigen Profile

Protein Summary

The protein encoded by this gene is a transformation and shape-change sensitive actin cross-linking/gelling protein found in fibroblasts and smooth muscle. Its expression is down-regulated in many cell lines, and this down-regulation may be an early and sensitive marker for the onset of transformation. A functional role of this protein is unclear. Two transcript variants encoding the same protein have been found for this gene.

Gene names and symbols associated with anti-Transgelin (TAGLN) Antibodies

  • transgelin (tagln) antibody
  • transgelin (LOC732906) antibody
  • transgelin (TAGLN) antibody
  • transgelin (tagl) antibody
  • transgelin (Tagln) antibody
  • MGC68550 antibody
  • MGC107855 antibody
  • Sm22 antibody
  • SM22A antibody
  • SMCC antibody
  • TAGLN1 antibody
  • WS3-10 antibody
  • Ws310 antibody
  • zgc:153186 antibody

Protein level used designations for anti-Transgelin (TAGLN) Antibodies

transgelin , putative transgelin , 22 kDa actin-binding protein , SM22-alpha , smooth muscle protein 22-alpha , transgelin variant 2 , SM22 , Sm22alpha , actin-associated protein p27 , smooth muscle 22 protein , 25 kDa F-actin-binding protein , sm22 , sm22alpha-b

GENE ID SPECIES
399014 Xenopus laevis
594967 Xenopus (Silurana) tropicalis
732906 Bombyx mori
100189993 Taeniopygia guttata
100528947 Ictalurus punctatus
6876 Homo sapiens
100009332 Oryctolagus cuniculus
21345 Mus musculus
25123 Rattus norvegicus
479424 Canis lupus familiaris
513463 Bos taurus
396490 Gallus gallus
397021 Sus scrofa
751758 Danio rerio
100728822 Cavia porcellus
Selected quality suppliers for anti-Transgelin (TAGLN) Antibodies
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