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anti-Transglutaminase 2 (C Polypeptide, Protein-Glutamine-gamma-Glutamyltransferase) (TGM2) Antibodies

Transglutaminases are enzymes that catalyze the crosslinking of proteins by epsilon-gamma glutamyl lysine isopeptide bonds. Additionally we are shipping Transglutaminase 2 (C Polypeptide, Protein-Glutamine-gamma-Glutamyltransferase) Proteins (30) and Transglutaminase 2 (C Polypeptide, Protein-Glutamine-gamma-Glutamyltransferase) Kits (28) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
TGM2 7052 P21980
TGM2 21817 P21981
TGM2 56083  
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Top anti-Transglutaminase 2 (C Polypeptide, Protein-Glutamine-gamma-Glutamyltransferase) Antibodies at antibodies-online.com

Showing 10 out of 284 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Dog Mouse Un-conjugated IF, IHC (p), IP, WB 0.1 mg Log in to see 10 to 12 Days
$554.40
Details
Cow Rabbit Un-conjugated WB WB Suggested Anti-TGM2 Antibody Titration: 0.2-1 ug/mlPositive Control: HepG2 cell lysate 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Rabbit Un-conjugated IHC (p), IP, WB 0.5 mg Log in to see 10 to 12 Days
$554.40
Details
Dog Mouse Un-conjugated Func, IF, IHC (p), IP, WB 0.1 mg Log in to see 10 to 12 Days
$589.05
Details
Chicken Rabbit Un-conjugated IHC, WB WB Suggested Anti-TGM2 Antibody Titration: 0.2-1 ug/mlPositive Control: HepG2 cell lysate IHC Information: Paraffin embedded placenta tissue, tested with an antibody dilution of 5 ug/ml. 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Rabbit Un-conjugated EIA, WB 0.4 mL Log in to see 6 to 8 Days
$390.50
Details
Human Goat Un-conjugated ELISA, WB ABIN190773 (0.03 ug/ml) staining of Human Lung lysate (35 ug protein in RIPA buffer).  Primary incubation was 1 hour.  Detected by chemiluminescence. 100 μg Log in to see 4 to 5 Days
$326.89
Details
Guinea Pig Mouse Un-conjugated IHC (p), IP, WB 0.1 mg Log in to see 10 to 12 Days
$554.40
Details
Human Rabbit Un-conjugated IHC (p), WB 0.1 mg Log in to see 6 to 8 Days
$390.50
Details
Mouse Goat Un-conjugated ELISA, WB 0.1 mg Log in to see 2 to 3 Days
$481.25
Details

TGM2 Antibodies by Reactivity, Application, Clonality and Conjugate

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Top referenced anti-Transglutaminase 2 (C Polypeptide, Protein-Glutamine-gamma-Glutamyltransferase) Antibodies

  1. Human Polyclonal TGM2 Primary Antibody for IHC (p), IP - ABIN181299 : Greenberg, Birckbichler, Rice: Transglutaminases: multifunctional cross-linking enzymes that stabilize tissues. in FASEB journal : official publication of the Federation of American Societies for Experimental Biology 1992 (PubMed)
    Show all 2 references for ABIN181299

  2. Human Polyclonal TGM2 Primary Antibody for EIA, WB - ABIN360168 : Parsons, Yosipovitch, Sheehan, Sangüeza, Greenberg, Sane: Transglutaminases: the missing link in nephrogenic systemic fibrosis. in The American Journal of dermatopathology 2007 (PubMed)

  3. Human Polyclonal TGM2 Primary Antibody for ELISA, WB - ABIN190773 : Verma, Wang, Manavathi, Fok, Mann, Kumar, Mehta: Increased expression of tissue transglutaminase in pancreatic ductal adenocarcinoma and its implications in drug resistance and metastasis. in Cancer research 2006 (PubMed)

  4. Dog (Canine) Monoclonal TGM2 Primary Antibody for IF, IHC (p) - ABIN180314 : Birckbichler, Upchurch, Patterson, Conway: A monoclonal antibody to cellular transglutaminase. in Hybridoma 1985 (PubMed)

  5. Chicken Polyclonal TGM2 Primary Antibody for IHC, WB - ABIN2782978 : Verma, Guha, Wang, Fok, Koul, Abbruzzese, Mehta: Tissue transglutaminase regulates focal adhesion kinase/AKT activation by modulating PTEN expression in pancreatic cancer cells. in Clinical cancer research : an official journal of the American Association for Cancer Research 2008 (PubMed)

  6. Cow (Bovine) Polyclonal TGM2 Primary Antibody for WB - ABIN2782979 : Li, Bagchi, Bagchi: Identification of a signaling pathway involving progesterone receptor, calcitonin, and tissue tranglutaminase in Ishikawa endometrial cells. in Endocrinology 2006 (PubMed)

More Antibodies against Transglutaminase 2 (C Polypeptide, Protein-Glutamine-gamma-Glutamyltransferase) Interaction Partners

Human Transglutaminase 2 (C Polypeptide, Protein-Glutamine-gamma-Glutamyltransferase) (TGM2) interaction partners

  1. High TGM2 expression is associated with gastric cancer progression.

  2. TGase 2 induces p53 (show TP53 Antibodies) depletion through transportation to p62 (show GTF2H1 Antibodies) in renal cell carcinoma (show MOK Antibodies).

  3. TG2 can inhibit tumor cell apoptosis through down-regulation of Bax (show BAX Antibodies) and prevention of release Cyt C (show CYCS Antibodies) from mitochondria into cytoplasm

  4. Case Report: mast cells recruited to the skin/bone marrow by CCL2 (show CCL2 Antibodies)/CCR (show POR Antibodies), may induce the development of pediatric mastocytosis by reducing IL-10 (show IL10 Antibodies) due to upregulating TG2 activity via transcription factor nuclear factor-kappaB.

  5. These findings suggest that TGM2-mediated autophagy and CDKN1A-mediated cell cycle arrest are two important barriers in the TP53 (show TP53 Antibodies) pathway that prevent oncogenic transformation.

  6. PKM2/TG2 interplay plays an important role in the regulation of autophagy in particular under cellular stressful conditions such as those displayed by cancer cells.

  7. W332F mutation led to significant changes of both the Km and the Vmax kinetic parameters of the isopeptidase reaction of TG2 while its calcium and GTP (show AK3 Antibodies) sensitivity was similar to the wild-type enzyme.

  8. The frequency of TG2-specific plasma cells in the celiac lesion is dynamically regulated in response to gluten exposure.

  9. A gain-of-function mutation in P2X7R (show P2RX7 Antibodies) associated with autoimmune disease caused enhanced TG2 externalization from cells, and this correlated with increased pore activity.

  10. We showed the appearance of transglutaminase (TG2) immunoreactivity in leukocytes in multiple sclerosis lesions, and particular in macrophages in rat chronic-relapsing experimental autoimmune encephalomyelitis.

Cow (Bovine) Transglutaminase 2 (C Polypeptide, Protein-Glutamine-gamma-Glutamyltransferase) (TGM2) interaction partners

  1. TG2 contributes to 5-hydroxytryptamine-induced distal pulmonary artery smooth muscle cell proliferation via promotion of AKT (show AKT1 Antibodies) signaling, likely via its serotonylation.

  2. An important role for TG2, mediated by intracellular calcium fluxes and HIF1A (show HIF1A Antibodies), in hypoxia-induced pulmonary artery smooth muscle cells proliferation.

  3. externalized GTP (show AK3 Antibodies)-bound TG2 serves as a molecular switch for differentiation of chondrocytes to a hypertrophic, calcifying phenotype in a manner that does not require either TG2 transamidation activity or fibronectin (show FN1 Antibodies) binding

Mouse (Murine) Transglutaminase 2 (C Polypeptide, Protein-Glutamine-gamma-Glutamyltransferase) (TGM2) interaction partners

  1. TG2 controls the formation of VEGF165-heparan sulfate proteoglycan complexes

  2. TG2 is a novel inhibitor of adipogenesis.

  3. LPS (show TLR4 Antibodies)-induced TG2 was involved in the mechanism of pinocytosis and phagocytosis in microglia.

  4. Inhibition of tissue transglutaminase resulted in a reduced rate of compaction compared to controls during early remodeling (up to 2 days). In contrast, inhibition of lysyl oxidase (show LOX Antibodies) did not alter the early compaction.

  5. TG2-deficient mice exhibited hyper inflammatory responses after being challenged with monosodium urate crystals.

  6. Data presented in this study show that TG2 plays a key role in cellular dynamics and consequently influences the energetic metabolism.

  7. TG2 functions as a critical signal for allergic lung responses.

  8. TG2 ablation had no effect on either motor or cognitive deficits, or on the weight loss.

  9. TG2 is an important mediator of endothelial cell inflammation and lung PMN (show TBCE Antibodies) sequestration associated with intravascular coagulation and sepsis

  10. TG2 promotes neointima formation by mediating the PDGF (show PDGFA Antibodies)-BB activation of the PDGFR (show PDGFRB Antibodies)/Akt1 (show AKT1 Antibodies) and beta-catenin (show CTNNB1 Antibodies) pathways in vascular smooth muscle cells.

Transglutaminase 2 (C Polypeptide, Protein-Glutamine-gamma-Glutamyltransferase) (TGM2) Antigen Profile

Protein Summary

Transglutaminases are enzymes that catalyze the crosslinking of proteins by epsilon-gamma glutamyl lysine isopeptide bonds. While the primary structure of transglutaminases is not conserved, they all have the same amino acid sequence at their active sites and their activity is calcium-dependent. The protein encoded by this gene acts as a monomer, is induced by retinoic acid, and appears to be involved in apoptosis. Finally, the encoded protein is the autoantigen implicated in celiac disease. Two transcript variants encoding different isoforms have been found for this gene.

Gene names and symbols associated with TGM2

  • transglutaminase 2, C polypeptide (Tgm2) antibody
  • transglutaminase 2 (TGM2) antibody
  • transglutaminase 2 (LOC100352148) antibody
  • transglutaminase 2 (C polypeptide, protein-glutamine-gamma-glutamyltransferase) (TGM2) antibody
  • transglutaminase 2b (tgm2b) antibody
  • fc12b04 antibody
  • G-ALPHA-h antibody
  • GNAH antibody
  • G[a]h antibody
  • TG2 antibody
  • TGase2 antibody
  • TgaseII antibody
  • TGC antibody
  • TGL2 antibody
  • TGM2 antibody
  • tTG antibody
  • tTGas antibody
  • wu:fc12b04 antibody
  • zgc:136700 antibody

Protein level used designations for TGM2

TGase C , protein-glutamine gamma-glutamyltransferase 2 , C polypeptide, protein-glutamine-gamma-glutamyltransferase , TG(C) , TGase H , TGase-2 , TGase-H , protein-glutamine-gamma-glutamyltransferase , tissue transglutaminase , transglutaminase C , transglutaminase H , transglutaminase-2 , TGC , C polypeptide , TG C , tissue-type transglutaminase , transglutaminase 2 (C polypeptide, protein-glutamine-gamma-glutamyltransferase)

GENE ID SPECIES
100379228 Cavia porcellus
7052 Homo sapiens
100352148 Oryctolagus cuniculus
396432 Gallus gallus
281528 Bos taurus
485867 Canis lupus familiaris
100127492 Sus scrofa
21817 Mus musculus
56083 Rattus norvegicus
323856 Danio rerio
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