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Transglutaminase 3 (E Polypeptide, Protein-Glutamine-gamma-Glutamyltransferase) Proteins (TGM3)

Transglutaminases are enzymes that catalyze the crosslinking of proteins by epsilon-gamma glutamyl lysine isopeptide bonds. Additionally we are shipping TGM3 Antibodies (93) and TGM3 Kits (13) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
TGM3 7053 Q08188
TGM3 21818 Q08189
TGM3 366189 D4A5U3
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Top TGM3 Proteins at antibodies-online.com

Showing 10 out of 13 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Baculovirus infected Insect Cells Human His tag 100 μg Log in to see 16 Days
$382.80
Details
HOST_Escherichia coli (E. coli) Mouse His tag 100 μg Log in to see 11 to 13 Days
$528.00
Details
Yeast Cow His tag   1 mg Log in to see 56 to 66 Days
$3,309.17
Details
Yeast Rat His tag   1 mg Log in to see 56 to 66 Days
$3,312.83
Details
Human Un-conjugated   100 μg Log in to see 4 to 5 Days
$150.48
Details
HOST_Escherichia coli (E. coli) Human Un-conjugated 100 μg Log in to see 11 to 13 Days
$792.00
Details
HOST_Escherichia coli (E. coli) Mouse Un-conjugated   100 μg Log in to see 9 to 19 Days
$715.97
Details
HOST_Escherichia coli (E. coli) Human Un-conjugated   100 μg Log in to see 9 to 19 Days
$967.75
Details

TGM3 Proteins by Origin and Source

Origin Expressed in Conjugate
Human , ,

Mouse (Murine)

Rat (Rattus)

More Proteins for Transglutaminase 3 (E Polypeptide, Protein-Glutamine-gamma-Glutamyltransferase) (TGM3) Interaction Partners

Human Transglutaminase 3 (E Polypeptide, Protein-Glutamine-gamma-Glutamyltransferase) (TGM3) interaction partners

  1. mRNA expression of transglutaminase 1 (show TGM1 Proteins) and transglutaminase 3 was significantly decreased in patients with chronic periodontitis compared with a healthy control group.

  2. Transglutaminase 3 present in the IgA aggregates in dermatitis herpetiformis skin is enzymatically active and binds soluble fibrinogen.

  3. New basal cell carcinoma susceptibility loci were identified at TGM3 (rs214782) and RGS22 (show RGS22 Proteins)(rs7006527).

  4. IgA-anti-TG1 antibodies were found in 2% and IgA-anti-TG3 antibodies in 3% of patients with active atopic dermatitis (AD). Two out of the 5 patients with AD and concomitant celiac disease had IgA-anti-TG1 and IgA-anti-TG2 (show TGM2 Proteins) antibodies.

  5. TGM3, a candidate tumor suppressor, contributes to the carcinogenesis and development of human head and neck cancer.

  6. Genetic variation in the epidermal transglutaminase genes is not associated with atopic dermatitis.

  7. The low expression of TGM3 may contribute to the carcinogenesis and development of laryngeal carcinoma.

  8. TGM3 in immunoglobulin A (IgA) and TGM3 immune complexes is responsible for cross-linking and tight binding of IgA to connective tissue in the dermis and explains the IgA deposits in dermatitis herpetiformis skin long after signs of disease are resolved.

  9. findings lend credence to the notion that TG3 and TG6 are involved in the gluten-induced autoimmune responses of dermatitis herpetiformis and gluten ataxia (show USP14 Proteins)

  10. new information on the specific distribution of TGase 3

Mouse (Murine) Transglutaminase 3 (E Polypeptide, Protein-Glutamine-gamma-Glutamyltransferase) (TGM3) interaction partners

  1. study concludes that the classic wellhaarig mutations result from defects in Tgm3

  2. The first signs of alopecia in mice of the +/Fgf5 (show FGF5 Proteins)(go-Y) we/wewal/wal genotype appear only three days later than in double +/+ we/wewal/wal homozygotes.

  3. Fluctuations of BMP2 (show BMP2 Proteins) signaling pathway during hair cycles in skin with mutant genes we, wal and Fgf5 (show FGF5 Proteins)(go).

  4. Interaction of mutant genes Fgf5 (show FGF5 Proteins)(go-Y), we, and wal changes the duration of hair growth cycles in mice

  5. The clinically uninvolved skin in TGM3 knockout mice showed impaired barrier function and higher susceptibility to FITC sensitization indicating that TGM3 has a significant contribution to the functionally intact cutaneous barrier.

  6. Loss of Tgm3 is associated with defective hair development.

  7. new information on the specific distribution of TGase 3

  8. The expression of TGM3 may play a important role in the epidermis differentiation in embryogenesis.

TGM3 Protein Profile

Protein Summary

Transglutaminases are enzymes that catalyze the crosslinking of proteins by epsilon-gamma glutamyl lysine isopeptide bonds. While the primary structure of transglutaminases is not conserved, they all have the same amino acid sequence at their active sites and their activity is calcium-dependent. The protein encoded by this gene consists of two polypeptide chains activated from a single precursor protein by proteolysis. The encoded protein is involved the later stages of cell envelope formation in the epidermis and hair follicle.

Gene names and symbols associated with TGM3

  • transglutaminase 3 (E polypeptide, protein-glutamine-gamma-glutamyltransferase) (TGM3)
  • transglutaminase 3 (TGM3)
  • transglutaminase 3, E polypeptide (Tgm3)
  • AI893889 protein
  • RGD1561831 protein
  • TG(E) protein
  • TGE protein

Protein level used designations for TGM3

E polypeptide, protein-glutamine-gamma-glutamyltransferase , TG(E) , TGase E , TGase-3 , protein-glutamine gamma-glutamyltransferase E , transglutaminase E , transglutaminase-3 , E polypeptide , TG E , TGE , protein-glutamine-gamma-glutamyltransferase

GENE ID SPECIES
100053068 Equus caballus
7053 Homo sapiens
477180 Canis lupus familiaris
505080 Bos taurus
21818 Mus musculus
366189 Rattus norvegicus
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